Ureteral catheters, bladder catheters, systems, kits and methods for inducing negative pressure to increase renal function
Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.
1. A ureteral catheter comprising (a) a proximal portion; and (b) a distal portion, the distal portion comprising a retention portion that comprises an outwardly facing side and an inwardly facing side, the inwardly facing side comprising one or more protected drainage holes, ports or perforations, the outwardly facing side being configured to establish an outer periphery or protective surface area that contacts and inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter.
2. The ureteral catheter according to claim 1 , wherein the one or more protected drainage holes, ports or perforations are disposed on a protected surface area or inner surface area of the retention portion, and wherein the outer periphery or protective surface area of the retention portion of the catheter is configured to support the mucosal tissue and thereby prevent occlusion of the one or more of the protected drainage holes, ports or perforations upon application of negative pressure through the ureteral catheter.
3. The ureteral catheter according to claim 1 , wherein the retention portion comprises one or more helical coils, each coil having an outwardly facing side and an inwardly facing side, and wherein the outer periphery or protective surface area comprises the outwardly facing side(s) of the one or more helical coil(s), and the one or more protected drainage holes, ports or perforations are disposed on the inwardly facing side(s) of the one or more helical coil(s).
4. The ureteral catheter according to claim 1 , wherein the retention portion is configured to be extended into a deployed position in which a diameter of the retention portion is greater than a diameter of the drainage lumen portion.
5. The ureteral catheter according to claim 1 , wherein the number of the drainage holes, ports or perforations towards the distal end of the retention portion is greater than the number of the drainage holes, ports or perforations towards the proximal end of the retention portion.
6. The ureteral catheter according to claim 1 , wherein the size of one or more of the drainage holes, ports or perforations towards the distal end of the retention portion is greater than the size of one or more of the drainage holes, ports or perforations towards the proximal end of the retention portion.
7. The ureteral catheter according to claim 1 , wherein the total area of the drainage holes, ports or perforations towards the distal end of the retention portion is greater than the total area of the drainage holes, ports or perforations towards the proximal end of the retention portion.
8. The ureteral catheter according to claim 1 , wherein the sidewall of the proximal portion of the ureteral catheter is essentially free or free of drainage openings.
9. A bladder catheter comprising (a) a proximal portion; and (b) a distal portion, the distal portion comprising a retention portion that comprises an outwardly facing side and an inwardly facing side, the inwardly facing side comprising one or more protected drainage holes, ports or perforations, the outwardly facing side being configured to establish an outer periphery or protective surface area that contacts and inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter.
10. The bladder catheter according to claim 9 , wherein the one or more protected drainage holes, ports or perforations are disposed on a protected surface area or inner surface area of the retention portion, and wherein the outer periphery or protective surface area of the retention portion of the catheter is configured to support the mucosal tissue and thereby prevent occlusion of the one or more of the protected drainage holes, ports or perforations upon application of negative pressure through the bladder catheter.
11. The bladder catheter according to claim 9 , wherein the retention portion comprises one or more helical coils, each coil having an outwardly facing side and an inwardly facing side, and wherein the outer periphery or protective surface area comprises the outwardly facing side(s) of the one or more helical coil(s), and the one or more protected drainage holes, ports or perforations are disposed on the inwardly facing side(s) of the one or more helical coil(s).
12. The bladder catheter according to claim 9 , wherein the retention portion is configured to be extended into a deployed position in which a diameter of the retention portion is greater than a diameter of the drainage lumen portion.
13. The bladder catheter according to claim 9 , wherein the number of the drainage holes, ports or perforations towards the distal end of the retention portion is greater than the number of the drainage holes, ports or perforations towards the proximal end of the retention portion.
14. The bladder catheter according to claim 9 , wherein the size of one or more of the drainage holes, ports or perforations towards the distal end of the retention portion is greater than the size of one or more of the drainage holes, ports or perforations towards the proximal end of the retention portion.
15. The bladder catheter according to claim 9 , wherein the total area of the drainage holes, ports or perforations towards the distal end of the retention portion is greater than the total area of the drainage holes, ports or perforations towards the proximal end of the retention portion.
16. The bladder catheter according to claim 9 , wherein the sidewall of the proximal portion of the ureteral catheter is essentially free or free of drainage openings.