IP Library Granted Patent US 11,378,546
Granted Patent B2
US 11,378,546 · App. 16/667,693 · Granted Jul 5, 2022

PH Meter

Inventors: Eric Lee (Acton, MA); Steve Roth (San Jose, CA); Thang Huy Vu (San Jose, CA)
G01N27/4167G01N27/301G01N27/4165G01N27/36
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Quick Facts
Patent No.
US 11,378,546
App. No.
16/667,693
Granted
Jul 5, 2022
Kind
B2
Abstract

Voltammetric sensors prepared from composite materials and optionally using microfabrication techniques enable detection of analyte in sample volumes under ten microliters.

Claims (17)

1. An electrochemical analyte sensor comprising a substrate coated with a functionalized anthraquinone moiety selected from the group consisting of:

2. The electrochemical analyte sensor of claim 1 , wherein the functionalized anthraquinone moiety is covalently bound to the substrate.

3. The electrochemical analyte sensor of claim 1 , wherein the substrate is a working electrode comprising a polymeric material composed of polyvinyl alcohol and silica.

4. The electrochemical analyte sensor of claim 1 , further comprising a reference electrode having a reference junction composed of a composite formed from an ionic liquid, a conductive material, and a polymer.

5. The electrochemical analyte sensor of claim 4 , wherein the conductive material is a conductive solid matrix comprising the ionic liquid and a carbon allotrope, and wherein the ionic liquid is a room temperature ionic liquid.

6. The electrochemical analyte sensor of claim 5 , wherein the room temperature ionic liquid is proton permeable.

7. The electrochemical analyte sensor of claim 5 , wherein the carbon allotrope is electrically conductive.

8. A device, comprising:

an analyte sensor comprising a substrate coated with a functionalized anthraquinone moiety selected from the group consisting of:

and

at least one of an electrical contact point for applying electrical current, a controller unit, a processor unit, a program, an algorithm, and a probe for performing voltammetric scanning of the analyte sensor, wherein simultaneous analyte concentration measurements are made at the analyte sensor.

9. The device of claim 8 , wherein the functionalized anthraquinone moiety is a redox active material.

10. The device of claim 8 , wherein the substrate is a working electrode comprising a polymeric material composed of polyvinyl alcohol and silica.

11. The device of claim 8 , wherein the analyte sensor comprises a reference electrode having a reference junction composed of a composite formed from an ionic liquid, a conductive material, and a polymer.

12. The device of claim 11 , wherein the conductive material is a conductive solid matrix comprising the ionic liquid and a carbon allotrope, and wherein the ionic liquid is a room temperature ionic liquid.

13. The device of claim 12 , wherein the room temperature ionic liquid is proton permeable.

14. The device of claim 12 , wherein the carbon allotrope is electrically conductive.