IP Library Granted Patent US 11,529,089
Granted Patent B2
US 11,529,089 · App. 16/672,177 · Granted Dec 20, 2022

Low power device with contingent scheduling

Inventor: Kent Leyde (Sammamish, WA)
Assignee: LivaNovaUSA, Inc.
A61B5/369A61B5/0006A61B5/024A61B5/4094A61B5/6814A61B5/7264G16H40/63A61B2560/0209
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Quick Facts
Patent No.
US 11,529,089
App. No.
16/672,177
Granted
Dec 20, 2022
Kind
B2
Abstract

Medical device systems and methods for operating medical device systems conserve energy by efficiently managing computational demands of the systems. A first analysis, having relatively lower computational processing demand than at least a second analysis, processes signals from a subject to determine a first estimate of a propensity for the subject to have a neurological event. If the first estimate meets a set of specified criteria, a second analysis is performed to determine a second estimate of the propensity for the subject to have a neurological event.

Claims (32)

1. A method of operating a medical device configured to monitor a subject, the method comprising:

receiving, at a processor, a first signal reflective of neurological activity of the subject from a sensor communicating with the subject;

performing, by the processor, a first analysis of the first signal to estimate a first deviation of the subject from a normal neurological condition, including analyzing the first signal by a first set of feature extractors, in response to receiving the first signal;

determining that the first deviation meets one or more specified criteria;

subsequent to the first deviation meeting the one or more specified criteria, receiving, at the processor, a second signal reflective of neurological activity of the subject; and

performing, by the processor, a second analysis of the second signal to estimate a second deviation of the subject from the normal neurological condition, including analyzing the second signal by a second set of feature extractors different from the first set of feature extractors, the first analysis requiring less computational power than the second analysis, in response to receiving the second signal.

2. The method of claim 1 , wherein receiving the first signal comprises receiving, at the processor set in a base mode, the first signal reflective of neurological activity of the subject from the sensor implanted intracranially in the subject.

3. The method of claim 1 , wherein receiving the first signal comprises receiving, at the processor set in a base mode, the first signal reflective of neurological activity of the subject from the sensor implanted adjacent to an identified epileptic focus.

4. The method of claim 1 , wherein the sensor comprises a grid electrode, a strip electrode, or a depth electrode.

5. The method of claim 1 , wherein at least one of the one or more specified criteria is customized to the subject.

6. The method of claim 1 , further comprising modifying at least one of the one or more specified criteria based on a result of at least one of the first analysis or the second analysis.

7. The method of claim 1 , wherein receiving the first signal comprises receiving, at the processor set in a base mode, the first signal reflective of neurological activity of the subject from the sensor communicating with the subject according to a sliding observation window.

8. The method of claim 7 , wherein the sliding observation window includes a first time period during which the subject is at a higher risk for a neurological event and a second time period during which the subject is at a lower risk for the neurological event.

9. The method of claim 8 , wherein the first time period and the second time period are based on at least one of a time of day or a status of the subject.

10. The method of claim 8 , wherein receiving the first signal further comprises receiving, at the processor set in the base mode, the first signal reflective of neurological activity according to a first monitoring protocol during the first time period and according to a second monitoring protocol during the second time period, wherein the second monitoring protocol is configured for at least one of energy saving or data minimization.

11. The method of claim 1 , wherein a deviation of the subject from the normal neurological condition corresponds to an adverse condition of the subject, the adverse condition being an episode of epilepsy, migraine, depression, Alzheimer's, Parkinson's Disease, dementia, attention deficit disorder, or an eating disorder.

12. The method of claim 1 , further comprising transitioning the processor from a base mode to an advanced mode in response to the first deviation meeting the one or more specified criteria, wherein the second analysis is performed by the processor.

13. A system configured to monitor a subject, comprising:

a processor; and

a non-transitory computer-readable medium storing instructions that, when executed by the processor, cause the processor to:

receive a first signal reflective of neurological activity of the subject from a sensor communicating with the subject;

perform a first analysis of the first signal to estimate a first deviation of the subject from a normal neurological condition, including analyzing the first signal by a first set of feature extractors, in response to receiving the first signal;

determine that the first deviation meets one or more specified criteria;

receive a second signal reflective of neurological activity of the subject subsequent in time to the first signal in response to transitioning the processor from a base mode to an advanced mode; and

perform a second analysis of the second signal to estimate a second deviation of the subject from the normal neurological condition, including analyzing the second signal by a second set of feature extractors different from the first set of feature extractors, the first analysis requiring less computational power than the second analysis, in response to receiving the second signal.

14. The system of claim 13 , wherein the instructions cause the processor to receive the first signal reflective of neurological activity of the subject from the sensor implanted intracranially in the subject.

15. The system of claim 13 , wherein the instructions cause the processor to receive the first signal reflective of neurological activity of the subject from the sensor implanted adjacent to an identified epileptic focus.

16. The system of claim 13 , wherein at least one of the one or more specified criteria is customized to the subject.

17. The system of claim 13 , wherein the instructions further cause the processor to modify at least one of the one or more specified criteria based on a result of at least one of the first analysis or the second analysis.

18. The system of claim 13 , wherein the instructions cause the processor to receive the first signal reflective of neurological activity of the subject from the sensor communicating with the subject according to a sliding observation window.

19. The system of claim 18 , wherein the instructions cause the processor to receive the first signal reflective of neurological activity according to a first monitoring protocol during the first time period and according to a second monitoring protocol during the second time period, wherein the second monitoring protocol is configured for at least one of energy saving or data minimization.

20. The system of claim 13 , wherein a deviation of the subject from the normal neurological condition corresponds to an adverse condition of the subject, the adverse condition being an episode of epilepsy, migraine, depression, Alzheimer's, Parkinson's Disease, dementia, attention deficit disorder, or an eating disorder.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Sep 20, 2021
From: ACF FINCO I LP
To: LIVANOVA USA, INC.
Reel/Frame 057552/0378 →
SECURITY INTEREST Recorded Aug 16, 2021
From: LIVANOVA USA, INC.
To: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
Reel/Frame 057188/0001 →
RELEASE OF SECURITY INTEREST Recorded Aug 16, 2021
From: ARES CAPITAL CORPORATION, AS AGENT FOR THE LENDERS
To: LIVANOVA USA, INC.
Reel/Frame 057189/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 30, 2020
From: LIVANOVA USA, INC.
To: ACF FINCO I LP, AS COLLATERAL AGENT
Reel/Frame 054881/0784 →
PATENT SECURITY AGREEMENT Recorded Jun 17, 2020
From: LIVANOVA USA, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 053673/0675 →