IP Library Granted Patent US 11,690,891
Granted Patent B2
US 11,690,891 · App. 16/673,845 · Granted Jul 4, 2023

Methods of treatment using decolorized

Inventors: Michael T. Yatcilla (Los Angeles, CA); Troy Smillie (Redondo Beach, CA); Joosang Park (Irvine, CA); Isabel Andrea Garcia Tornadu (Buenos Aires, AR); Andrea Bertocco (Stanmore, GB); Kan He (Los Angeles, CA)
Assignee: Herbalife International of America, Inc.
A61K36/886A61K9/0053
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Quick Facts
Patent No.
US 11,690,891
App. No.
16/673,845
Granted
Jul 4, 2023
Kind
B2
Abstract

Provided herein is a method for improving the health of an intestinal epithelial barrier using Aloe vera . The method may include administering Aloe vera extracts to intestinal epithelial cells. The decolorized aloe extract may be whole leaf extract, whole leaf dry extract, inner leaf dry extract, digested whole leaf extract, digested whole leaf dry extract, digested inner leaf dry extract, or a combination thereof.

Claims (10)

1. A method for repairing wound injury to the epithelial cell barrier between the inside of the small intestines and the rest of the body of a human in need thereof consisting essentially of:

identifying a human in need of repairing wound injury to the epithelial cell barrier between the inside of the small intestine and the rest of the body of the human in need thereof; and

administering to the human in need thereof a decolorized Aloe vera extract, wherein the Aloe vera extract is selected from the group consisting of whole leaf Aloe vera extract, whole leaf dry Aloe vera extract, inner leaf dry Aloe vera extract, digested whole leaf Aloe vera extract, digested whole leaf dry Aloe vera extract, digested inner leaf dry Aloe vera extract, or a combination thereof, wherein the Aloe Vera extract is administered at a concentration of about 0.5 mg/ml to about 2 mg/ml to the human in need thereof to effectively repair the wound injury to the epithelial cell barrier between the inside of the small intestines and the rest of the body of the human in need thereof.

2. The method of claim 1 , wherein the Aloe vera extract is administered at a concentration of about 1 mg/ml.

3. The method of claim 1 , wherein the Aloe vera extract is a whole leaf extract.

4. The method of claim 1 , wherein the Aloe vera extract is a whole leaf dry extract.

5. The method of claim 1 , wherein the Aloe vera extract is an inner leaf dry extract.

6. The method of claim 1 , wherein the Aloe vera extract is a digested whole leaf extract.

7. The method of claim 1 , wherein the Aloe vera extract is a digested whole leaf dry extract.

8. The method of claim 1 , wherein the Aloe vera extract is a digested inner leaf dry extract.

Assignments (6)
PATENT SECURITY AGREEMENT - NOTES Recorded Apr 29, 2026
From: HERBALIFE INTERNATIONAL OF AMERICA, INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 075494/0972 →
RELEASE OF PATENT SECURITY AGREEMENT RECORDED AT REEL 067091/FRAME 0032 AND REEL 067091/FRAME 0325 Recorded Apr 29, 2026
From: CITIBANK, N.A.
To: HERBALIFE INTERNATIONAL, INC.; HERBALIFE INTERNATIONAL OF AMERICA, INC.
Reel/Frame 075499/0715 →
ASSIGNMENT OF PATENT SECURITY AGREEMENT Recorded Apr 30, 2024
From: JEFFERIES FINANCE LLC, AS RESIGNING AGENT
To: CITIZENS BANK, N.A., AS SUCCESSOR AGENT
Reel/Frame 067265/0162 →
SECURITY INTEREST Recorded Apr 12, 2024
From: HERBALIFE INTERNATIONAL OF AMERICA, INC.
To: CITIBANK, N.A., AS NOTES COLLATERAL AGENT
Reel/Frame 067091/0325 →
SECURITY INTEREST Recorded Mar 17, 2021
From: HERBALIFE INTERNATIONAL OF AMERICA, INC.
To: JEFFERIES FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 055623/0783 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 24, 2020
From: YATCILLA, MICHAEL T; SMILLIE, TROY; PARK, JOOSANG; TORNADU, ISABEL ANDREA GARCIA; BERTOCCO, ANDREA; HE, KAN
To: HERBALIFE INTERNATIONAL OF AMERICA, INC.
Reel/Frame 053304/0669 →
Continuity (2)
Provisional Application 62756449 · Nov 6, 2018
Related Publication 20200138895A1 · May 7, 2020