IP Library › Granted Patent US 10,696,673
Granted Patent B2
US 10,696,673 · App. 16/681,213 · Granted Jun 30, 2020

Bicyclic inhibitors of histone deacetylase

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Quick Facts
Patent No.
US 10,696,673
App. No.
16/681,213
Granted
Jun 30, 2020
Kind
B2
Abstract

Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2).

Claims (5)

1. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.

3. A method of inhibiting HDAC activity in a subject comprising the step of administering to the subject in need thereof an effective amount of a compound of claim 1 , or a pharmaceutically acceptable salt thereof.

Assignments (5)
SECURITY INTEREST Recorded Feb 13, 2026
From: ALKERMES, INC.
To: JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT
Reel/Frame 073790/0950 →
RELEASE OF SECURITY INTEREST IN PATENTS PREVIOUSLY RECORDED AT REEL/FRAME (072656/0509) Recorded Feb 13, 2026
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: ALKERMES, INC.
Reel/Frame 074858/0481 →
SECURITY INTEREST Recorded Oct 23, 2025
From: ALKERMES, INC.
To: JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT
Reel/Frame 072656/0509 →
CHANGE OF NAME Recorded Dec 1, 2020
From: RODIN THERAPEUTICS, INC.
To: ALKERMES, INC.
Reel/Frame 054504/0354 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 6, 2020
From: FULLER, NATHAN OLIVER; LOWE, JOHN A., III
To: RODIN THERAPEUTICS, INC.
Reel/Frame 051742/0265 →