Granted Patent
B2
US 11,299,491 · App. 16/685,841 · Granted Apr 12, 2022
Synthesis of key intermediate of KRAS G12C inhibitor compound
Inventors:
Andrew Thomas Parsons (Thousand Oaks, CA); Brian McNeil Cochran (Thousand Oaks, CA); William Powazinik, IV (Thousand Oaks, CA); Marc Anthony Caporini (Thousand Oaks, CA)
Assignee:
AMGEN INC.
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Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
Claims (1)
1. A compound, wherein the compound is:
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 23, 2020
From: PARSONS, ANDREW THOMAS; COCHRAN, BRIAN MCNEIL; POWAZINIK, WILLIAM, IV; CAPORINI, MARC ANTHONY
To: AMGEN INC.
Reel/Frame 053017/0393 →
Continuity (2)
Provisional Application
62768802
· Nov 16, 2018