Modular pulsed pressure device for the transport of liquid cryogen to a cryoprobe
A cryogenic medical device for delivery of subcooled liquid cryogen to various configurations of cryoprobes is designed for the treatment of damaged, diseased, cancerous or other unwanted tissues. The device is a closed or semi-closed system in which the liquid cryogen is contained in both the supply and return stages. The device is capable of generating cryogen to a supercritical state and may be utilized in any rapid cooling systems. As designed, the device comprises a number of parts including a vacuum insulated outer dewar, submersible cryogen pump, baffled linear heat exchanger, multiple pressurization cartridges, a return chamber, and a series of valves to control the flow of the liquid cryogen. The cryogenic medical device promotes the subcooling to any external cryogenic instrument.
1. A method of delivering cryogen to a cryoprobe, said method comprising the steps of:
providing a device containing the cryogen, said device having one or more ports;
providing a pump submersed within the cryogen;
providing a plurality of pressurized apparatuses within said device and coupled to said pump, each of said plurality of pressurized apparatuses having an immersion heater contained therein, at least one inlet port, and at least one outlet port;
providing an instrument outside said device for use in cooling processes, said instrument connected to one or more supply lines which interconnect with said device;
activating a first pressurized apparatus of said plurality of pressurized apparatuses to form a first volume of pressurized cryogen;
directing said first volume of pressurized cryogen to said instrument through said one or more supply lines;
directing a second volume of cryogen to a second pressurized apparatus of said plurality of pressurized apparatuses; and
activating a third pressurized apparatus of said plurality of pressurized apparatuses to form a third volume of pressurized cryogen wherein the step of directing the first volume of pressurized cryogen to said instrument, the step of directing the second volume of cryogen to the second pressurized apparatus, and the step of activating the third pressurized apparatus to form the third volume of pressurized cryogen are performed simultaneously.
2. The method of claim 1 , further comprising a step of delivering said first volume of pressurized cryogen to a heat exchanger prior to said step of directing said first volume of pressurized cryogen to said instrument.
3. The method of claim 1 , further comprising a step of sealing said device to form a closed system.
4. The method of claim 1 , wherein said instrument is a cryoprobe utilized in cryotherapeutic procedures.
5. The method of claim 1 , wherein said plurality of pressurized apparatuses are arranged in a series of pressurized apparatuses.
6. The method of claim 1 , further comprising a step of recirculating the cryogen through said device by way of one or more return lines.
7. The method of claim 1 , further comprising a step of generating the first volume of pressurized cryogen as supercritical cryogen within said first pressurized apparatus.
8. The method of claim 1 , further comprising directing the third volume of pressurized cryogen to the instrument after the first volume of pressurized cryogen has been directed to the instrument to maintain a continuous flow of pressurized cryogen to the instrument.
9. The method of claim 1 , further comprising activating the second pressurized apparatus after the second volume of cryogen has been directed to the second pressurized apparatus to form a second volume of pressurized cryogen.
10. The method of claim 1 , wherein each pressurized apparatus of said plurality of pressurized apparatuses comprises an immersion heater.
11. The method of claim 1 , further comprising directing said first volume of pressurized cryogen to a subcooling unit prior to directing said first volume of pressurized cryogen to said instrument.
12. The method of claim 11 , wherein the subcooling unit comprises a linear heat exchanger.
13. The method of claim 12 , wherein the linear heat exchanger comprises a plurality of baffles projecting into a flow path of the first volume of pressurized cryogen.
14. The method of claim 12 , wherein the linear heat exchanger comprises an interior central component configured as a spiral to increase a flow path of the first volume of pressurized cryogen in the heat exchanger.