WOUND DRESSING MATERIALS INCORPORATING ANTHOCYANINS DERIVED FROM FRUIT OR VEGETABLE SOURCES
A wound dressing composition, such as gauze, bandages, and surgical tapes comprising a substrate material impregnated with a pH sensitive dye composition comprising at least one anthocyanin derived from fruit or vegetable sources, and methods of use thereof.
1 .- 32 . (canceled)
33 . A method of manufacturing a wound dressing, comprising:
providing a substrate material; and
disposing pH sensitive dye composition comprising at least one fruit or vegetable derived anthocyanin within the substrate material.
34 . The method of claim 33 , wherein the at least one anthocyanin is derived from a raspberry ( Rubus sp.).
35 . The method of claim 33 , wherein the at least one anthocyanin is derived from a fruit or vegetable selected from the group consisting of a red cabbage, purple cabbage, purple carrots, elderberry, hibiscus, purple potato, red currant, black currants, blueberries, cherries, purple grapes, red raspberries and black raspberries.
36 . The method of claim 33 , wherein the substrate material is a woven or non-woven material.
37 . The method of claim 33 , wherein the substrate material comprises a fabric, cloth or sponge material.
38 . The method of claim 33 , where the substrate material comprises natural or synthetic fibers.
39 . The method of claim 33 , where the substrate material is an absorbent or water-permeable material.
40 . The method of claim 33 , where the substrate material comprises cotton.
41 . The method of claim 33 , wherein substrate material comprises cotton gauze.
42 . The method of claim 33 , wherein the wound dressing is selected from the group consisting of a pad, wrap, bandage, tape, cotton-tipped stick and adhesive strip bandage.
43 . The method of claim 33 , wherein the at least one anthocyanin is selected from the group consisting of cyaniding-3-sophoraside, cyanide-3-glucoside or pelargonidin-3-sophoroside.
44 . The method of claim 33 , wherein the at least one anthocyanin is an anthocyanadin derivative selected from the group consisting of cyandin, delphinidin, peonidin, petunidin, pelargonidin and malvidin anthocyanadin derivatives.
45 . The method of claim 33 , wherein the pH sensitive dye composition is sensitive at least within a pH range of pH 4.0 to pH 12.0, inclusive.
46 . The method of claim 33 , wherein the method further comprises disposing at least one therapeutic agent selected from the group consisting of antimicrobial agents, antiseptic agents, anti-inflammatory agents, pain relieving agents, wound closing adhesive agents, and antihistamine agents on the wound dressing.
47 . The method of claim 33 , wherein the pH sensitive dye composition comprises a mordant.
48 . The method of claim 47 , wherein the mordant is selected from the group consisting of aluminum potassium sulfate, copper sulfate, iron (III) oxide, copper sulfate, citric acid, iron (III) sulfate (Fe 2 (SO 4 ) 3 ) and sodium sulfate.
49 . The method of claim 47 , wherein the mordant is aluminum potassium sulfate.