Glucose biosensor encasement, glucose biosensor package, and method
A glucose biosensor encasement includes a first membrane and a second membrane. The first membrane has a first interlocking segment. The second membrane has a second interlocking segment cooperating with the first interlocking segment of the first membrane to provide a cavity between the first membrane and the second membrane configured to receive a glucose sensor. At least one of the first membrane and the second membrane comprises a semi-permeable portion configured to regulate diffusion characteristics of glucose through the membrane to realize a sensitivity for a sensor in the cavity. A method is also provided.
1. A glucose biosensor encasement, comprising:
a first flexible membrane having a first interlocking elongate segment;
a second flexible membrane having a second interlocking elongate segment and the first and second interlocking elongate segments cooperate to form an elongate undercut mechanical interlock along a peripheral edge between the first flexible membrane and the second flexible membrane with the first interlocking elongate segment and cooperate to provide a cavity between the first membrane and the second membrane configured to receive a glucose sensor and provide resistance to edge peeling about a periphery of the cavity to realize a desired sensitivity for the glucose sensor; and
at least one of the first membrane and the second membrane comprising a semi-permeable portion comprising a diffusion layer configured to regulate diffusion characteristics of glucose through the membrane to realize a sensitivity for a sensor in the cavity; wherein:
the first interlocking segment comprises an elongate ridge and the second interlocking segment comprises a channel having an ensmalled distal width and an enlarged proximal width complementary to the elongate ridge and interlocking in assembly.
2. The encasement of claim 1 , wherein the first interlocking segment is part of the first membrane and the second interlocking segment is part of the second membrane and the first interlocking segment and the second interlocking segment form a dovetail joint between the first membrane and the second membrane.
3. The encasement of claim 1 , wherein the first interlocking segment and the second interlocking segment form a u-shaped interlocking seam between the first membrane and the second membrane extending about an outer periphery of the cavity.
4. The encasement of claim 1 , wherein a plurality of discrete first interlocking segments and a complementary plurality of discrete second interlocking segments are provided spaced apart about an outer periphery of the cavity between the first membrane and the second membrane.
5. The encasement of claim 1 , wherein the first interlocking segment and the second interlocking segment are each provided respectively proximate an outer periphery of the first membrane and the second membrane.
6. The encasement of claim 1 , wherein the first membrane and the second membrane cooperate to provide a plurality of spaced-apart sensor cavities, at least one pair of first interlocking segment and second interlocking segment provided proximate each sensor cavity.
7. The encasement of claim 1 , wherein the first interlocking segment and the second interlocking segment substantially encompass the sensor cavity.
8. The encasement of claim 1 , wherein the first interlocking segment comprises an elongate trench having an ensmalled cross-sectional portion distal of the first membrane and the second interlocking segment comprises an elongate rib having an enlarged cross-sectional portion proximal of the first membrane.
9. The encasement of claim 8 , wherein the second interlocking segment is a mask layer deposited at least in part within the trench.
10. A glucose biosensor package, comprising:
a first flexible membrane having a first interlocking elongate portion;
a second flexible membrane having a second interlocking elongate portion having an elongate undercut mechanical interlock along a peripheral edge of the first flexible membrane and the second flexible membrane that cooperates with the first interlocking elongate portion of the first membrane to physically lock together the first membrane and the second membrane and provide a cavity between the first membrane and the second membrane configured to receive a biosensor resistant to edge peeling;
a biosensor having at least one sensing element contained in the cavity; and
at least one of the first membrane and the second membrane comprising a semi-permeable portion comprising a diffusion layer configured to regulate diffusion characteristics of glucose through the membrane to realize a sensitivity for the biosensor in the cavity; wherein:
the first interlocking portion comprises an elongate ridge and the second interlocking portion comprises an elongate channel having an ensmalled distal width and an enlarged proximal width complementary to the elongate ridge and interlocking in assembly.
11. The glucose biosensor package of claim 10 , wherein the first interlocking portion of the first membrane comprises at least one elongate interlocking segment and the second interlocking portion of the second layer comprises a second complementary at least one elongate interlocking segment of the second membrane.
12. The glucose biosensor package of claim 11 , wherein the second membrane comprises a semi-permeable portion proximate a sensing element of the biosensor.
13. The glucose biosensor package of claim 10 , wherein the first membrane comprises an insulating base layer and a pair of deposited interlocking rail segments each affixed in aligned interlocking relation with the base layer with in respective recess slots.
14. The glucose biosensor package of claim 10 , wherein the elongate ridge and the elongate channel form an elongate dovetail joint.