METAL COMPLEX OR METAL CHELATE COMPOSITIONS COMPRISING MINIMAL NANOPARTICLES
The present disclosure generally relates to metal complex or metal chelate compositions comprising minimal nanoparticles wherein the compositions maintain flowability.
1 . A metal complex or metal chelate composition with a water content of less than about 15% and less than about 1% nanoparticles by total weight of the composition.
2 . The metal complex or metal chelate composition of claim 1 , wherein the metal complex or metal chelate comprises an amino acid ligand.
3 . The metal complex or metal chelate composition of claim 1 , wherein the water activity measure of the composition is less than about 0.5.
4 . The metal complex or metal chelate composition of claim 1 , wherein the composition has less than about 0.5% nanoparticles by total weight of the composition.
5 . The metal complex or metal chelate composition of claim 4 , wherein the composition has less than about 0.25% nanoparticles by total weight of the composition.
6 . The metal complex or metal chelate composition of claim 4 , wherein the composition has less than about 0.1% nanoparticles by total weight of the composition.
7 . The metal complex or metal chelate composition of claim 1 , wherein the composition has a water content of less than about 12%.
8 . The metal complex or metal chelate composition of claim 7 , wherein the composition has a water content of less than about 10%.
9 . The metal complex or metal chelate composition of claim 7 , wherein the composition has a water content of less than about 8%.
10 . The metal complex or metal chelate composition of claim 7 , wherein the composition has a water content of less than about 6%.
11 . The metal complex or metal chelate composition of claim 1 , wherein the composition is stored in moisture resistant packaging.
12 . The metal complex or metal chelate composition of claim 1 , wherein the water content is measured at the end of the manufacturing run or after the composition has been stored for about 3 months in moisture resistant packaging.
13 . The metal complex or metal chelate composition of claim 1 , wherein the composition has excellent flowability, as determined by a Hausner ratio of less than 1.25 or a Flowdex index of less than 20.
14 . The metal complex or metal chelate composition of claim 1 , wherein the metal is selected from the group consisting of iron, magnesium, zinc, calcium, and combinations thereof.
15 . An animal feed comprising, the animal feed comprising a metal complex or metal chelate of claim 1 .
16 . A metal complex or metal chelate composition with excellent flowability as determined by a Hausner ratio of less than 1.12 or a Flowdex index of less than 10, wherein the composition has less than 1% nanoparticles by total weight of the composition.
17 . A method for administering an organic metal complex or metal chelate to a subject, the method comprising administering a metal complex or metal chelate composition of claim 1 .
18 . The method of claim 17 in which the composition is administered for hematologic support, energy supplementation, mental acuity, memory and cognition support, cardiovascular, hepatic or neurologic support.