Medical unit dose container
A unit dose container for the containment of an intranasal formulation for use with the POD device.
1. A device for delivering a compound to an olfactory region of a nasal cavity comprising:
a canister configured to contain a propellant,
a tip configured to removably couple to a housing body of the device, the tip comprising:
a container cavity configured to receive a unit dose container, the unit dose container configured to contain the compound,
a diffuser configured to be in communication with the canister such that propellant exiting the canister travels through the diffuser, and
a nozzle in communication with the container cavity; and
a puncture member that is configured to, upon coupling the tip to the housing body, puncture an end of the unit dose container such that following contact with the diffuser, the diffused propellant contacts the compound contained in the unit dose container,
wherein the device is capable of delivering the compound to the olfactory region of the nasal cavity.
2. The device of claim 1 , further comprising an additional puncture member, wherein the additional puncture member is configured to puncture a second end of the unit dose container.
3. The device of claim 1 , wherein the puncture member has an angle of puncture between 15 degrees and 90 degrees, inclusive.
4. The device of claim 1 , wherein the puncture member further comprises a side orifice.
5. The device of claim 1 , wherein the compound is an intranasal formulation.
6. The device of claim 1 , wherein the end of the unit dose container further includes a rubber stopper or a foil seal or combinations thereof.
7. The device of claim 1 , wherein the end of the unit dose container includes a puncture area.
8. The device of claim 7 , wherein the puncture area is a dimple.
9. The device of claim 1 , wherein the puncture member is composed of metal or a polymer or combinations thereof.
10. The device of claim 1 , further comprising a connection channel having a first end and a second end, where the first end is coupled to the canister and the second end is coupled to the diffuser, wherein a diameter of the diffuser across an opening of the container cavity is greater than a diameter of the connection channel.
11. The device of claim 1 , wherein the puncture member comprises a rear puncture member positioned on the housing body, the device further comprising a front puncture member positioned on the tip, wherein each puncture member is configured to puncture a respective end of the unit dose container.
12. The device of claim 1 , wherein the puncture member comprises a hollow channel for delivery of the propellant into the unit dose container.
13. The device of claim 1 , wherein the puncture member is composed of a porous material for delivery of the propellant into the unit dose container.
14. The device of claim 1 , wherein the tip is configured to translate relative to the housing body.
15. The device of claim 1 wherein the tip and the housing body each have respective threaded interfaces that are configured to mate.
16. A device for delivering a compound to an olfactory region of a nasal cavity comprising:
a canister configured to contain a propellant,
a tip configured to removably couple to a housing body of the device, the tip comprising:
a container cavity configured to receive a unit dose container, the unit dose container configured to contain the compound,
a diffuser configured to be in communication with the canister such that propellant exiting the canister travels through the diffuser, and
a nozzle in communication with the container cavity; and
a puncture member that is configured to upon coupling the tip to the housing body, puncture an end of the unit dose container,
wherein the device is capable of delivering the compound to the olfactory region of the nasal cavity.
17. The device of claim 16 , wherein the puncture member is porous such that, upon actuation, propellant exiting the canister comes into contact with the puncture member.
18. The device of claim 16 , wherein the puncture member is a rear puncture member configured to puncture a proximal end of the unit dose container, the device further comprising a front puncture member positioned on the tip and configured to puncture a distal end of the unit dose container.
19. The device of claim 16 , further comprising one or more ribs along the length of the unit dose container.
20. The device of claim 16 , wherein an end of the unit dose container includes a puncture area.