Water soluble compositions comprising purified cannabinoids
This disclosures relates to new compositions and methods for making cannabinoid formulations. In one embodiment, this disclosure provides water soluble compositions comprising a first purified cannabinoid and Vitamin E TPGS. In one embodiment, the disclosure herein comprises a method of making powders comprising heatings material to a first temperature and a second temperature.
1. A liquid composition, comprising:
one or more purified cannabinoids;
one or more purified terpenes;
Vitamin E TPGS; and
water.
2. The liquid composition of claim 1 , comprising a ratio of Vitamin E TPGS to the one or more purified cannabinoids of about 85:15 to about 75:25 by percent mass.
3. The liquid composition of claim 1 , comprising a ratio of Vitamin E TPGS to the one or more purified cannabinoids of about 82:18 to about 78:22 by percent mass.
4. The liquid composition of claim 1 , comprising a micelle.
5. A method of making a liquid composition having one or more purified cannabinoids and one or more purified terpenes, comprising:
separating one or more purified cannabinoids and one or more purified terpenes from a cannabis plant material;
adding the one or more purified cannabinoids and the one or more purified terpenes to Vitamin E TPGS to create a mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more purified terpenes;
heating said mixture to a first temperature;
adding water to the mixture to create an aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes; and
cooling the aqueous formulation to a second temperature.
6. The method of claim 5 , comprising:
sonicating the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes to create micelles;
freezing the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes;
lowering pressure of the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes;
removing water from the aqueous formulation comprising the mixture of Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes to create a dry powder; and
adding water to the dry powder to create a liquid cannabinoid composition comprising Vitamin E TPGS and the one or more purified cannabinoids and one or more terpenes.
7. The method of claim 6 , wherein the dry powder comprises reverse micelles.
8. The method of claim 6 , wherein the first temperature is between 70-90 degrees Celsius; and wherein the second temperature is between 0-50 degrees Celsius.
9. The liquid composition of claim 1 , wherein the one or more purified cannabinoids is THCA, CBC, THC, CBN, CBD, CBG, CBGA, CBDA, or a combination thereof.
10. The liquid composition of claim 1 , wherein the one or more purified cannabinoids is CBD, THC, THCV, or a combination thereof.
11. The liquid composition of claim 10 , wherein the combination comprises THC, CBD and THCV.
12. The liquid composition of claim 1 , wherein the one or more purified terpenes is linalool, alpha-pinene, alpha-humulene, terpinolene, eucalyptol, pulegone, terpineol, beta-caryophyllene, cymene, or a combination thereof.
13. The liquid composition of claim 11 , wherein the liquid composition comprises beta-caryophyllene, linalool, and cymene as purified terpenes.
14. The liquid composition of claim 4 , wherein the one or more cannabinoids and/or the one or more terpenes are contained within the micelles.
15. The liquid composition of claim 1 , comprising a ratio of Vitamin E TPGS to a combined amount of the one or more purified cannabinoids and the one or more purified terpenes of about 85:15 to about 75:25 by percent mass.
16. The liquid composition of claim 1 , comprising a ratio of Vitamin E TPGS to a combined amount of the one or more purified cannabinoids and the one or more purified terpenes of about 85:15 to about 75:25 by percent mass.
17. The method of claim 6 , wherein adding water to the dry powder creates a liquid cannabinoid composition comprising Vitamin E TPGS and between 5 to 20 mg of the one or more purified cannabinoids and one or more terpenes per mL of water.