Stentriever devices for removing an occlusive clot from a vessel and methods thereof
Devices described herein include a stentriever for removing an occlusive clot. The stentriever can include a membrane cover on the proximal end which can be sized to form a seal with the tip of an intermediate catheter. Clot engagement sections and/or a distal engagement section of the stentriever can also include a full or partial membrane covering to control the direction of aspiration and/or areas where the aspiration applies suction to the thrombus or clot. The membranes can be used to direct the aspiration so as to pull the clot deeper into the clot engagement sections of the stentriever, thereby improving grip on the clot. The design can also increase the effectiveness of clot fragment protection for friable clots by providing pores and/or clot cells in a distal engagement section.
1. A stentriever for removing a clot from a vessel, comprising:
a shaft extending between a proximal end and a distal end;
a first expandable clot engagement section directly connected to and extending from the shaft and comprising a first clot engagement membrane directing an aspiration into the first expandable clot engagement section;
a second expandable clot engagement section extending from the shaft and positioned distal to the first expandable clot engagement section;
an intermediate flow channel positioned proximal to and adjacent the second expandable clot engagement section;
a proximal flow channel positioned proximal to and adjacent the first expandable clot engagement section, the proximal flow channel comprising a proximal flow membrane directing the aspiration from the first expandable clot engagement section and to the proximal flow channel; and
a distal engagement section positioned distal to the first expandable clot engagement section and extending from the shaft,
wherein the stentriever comprises a collapsed configuration to be inserted into a microcatheter,
wherein the stentriever comprises an expanded configuration for exerting an outward radial force on the clot, and
wherein, when the stentriever is in the expanded configuration, the first expandable clot engagement section has a larger diameter than the proximal flow channel, causing the aspiration to be directed from the first expandable clot engagement section by the first clot engagement membrane and into the proximal flow channel.
2. The stentriever of claim 1 , wherein the first expandable clot engagement section further comprises a first clot inlet capturing the clot.
3. The stentriever of claim 1 , wherein the proximal flow channel comprises:
a collapsed configuration to be inserted into the microcatheter, and
an expanded configuration wherein the proximal flow channel exerts a radial force on an intermediate catheter,
wherein, in the expanded configuration, the proximal flow membrane engages with an inner surface of the intermediate catheter at a proximal seal area to direct aspiration flow.
4. The stentriever of claim 1 , wherein the second expandable clot engagement section comprises a second clot engagement membrane directing the aspiration into the second expandable clot engagement section.
5. The stentriever of claim 1 , wherein the distal engagement section comprises a plurality of distal clot cells capturing clot fragments.
6. The stentriever of claim 5 , wherein the distal engagement section comprises a distal membrane, and wherein the distal membrane comprises distal pores constricting flow of the aspiration into the distal engagement section.
7. The stentriever of claim 6 , wherein:
the first expandable clot engagement section further comprises a first clot inlet capturing the clot, and
the distal membrane constricts flow from the distal engagement section to the proximal flow channel to create a negative pressure at the first expandable clot engagement section, thereby pulling the clot into the first clot inlet.
8. A system for removing a clot from a vessel, the system comprising:
a stentriever comprising:
a shaft extending between a proximal end and a distal end;
a first expandable clot engagement section directly connected to and extending from the shaft and comprising a first clot engagement membrane directing an aspiration into the first expandable clot engagement section;
a second expandable clot engagement section extending from the shaft and positioned distal to the first expandable clot engagement section;
an intermediate flow channel positioned proximal to and adjacent the second expandable clot engagement section;
a proximal flow channel positioned proximal to and adjacent the first expandable clot engagement section, the proximal flow channel comprising a proximal flow membrane; and
a distal engagement section positioned distal to the first expandable clot engagement section and extending from the shaft; and
an intermediate catheter,
wherein the stentriever comprises a collapsed configuration to be inserted into a microcatheter,
wherein the stentriever comprises an expanded configuration to be expanded in the vessel,
wherein, in the expanded configuration, the proximal flow channel exerts a radial force on the intermediate catheter,
wherein the proximal flow membrane seals against an inner surface of the intermediate catheter, and
wherein, when the stentriever is in the expanded configuration, the first expandable clot engagement section has a larger diameter than the proximal flow channel, causing the aspiration to be directed from the first expandable clot engagement section by the first clot engagement membrane and into the proximal flow channel.
9. The system of claim 8 , wherein the first expandable clot engagement section further comprises a first clot inlet capturing the clot.
10. The system of claim 8 , wherein the second expandable clot engagement section comprises a second clot engagement membrane directing an aspiration into the second expandable clot engagement section.
11. The system of claim 8 , wherein the distal engagement section comprises a plurality of distal pores constricting flow of the aspiration into the distal engagement section.
12. A stentriever for removing a clot from a vessel, comprising:
a shaft extending between a proximal end and a distal end;
a first expandable clot engagement section directly connected to and extending from the shaft and comprising a first clot engagement membrane directing an aspiration into the first expandable clot engagement section;
a second expandable clot engagement section extending from the shaft, the second expandable clot engagement section being positioned distal to the first expandable clot engagement section, the second expandable clot engagement section comprising a second clot engagement membrane directing the aspiration into the second expandable clot engagement section;
a distal engagement section positioned distal to the first expandable clot engagement section and the second expandable clot engagement section and extending from the shaft; and
an inner channel extending from a position proximal to and adjacent the first expandable clot engagement section to a position proximate the distal engagement section, the inner channel comprising:
a first inner channel membrane positioned along a length of the inner channel proximal to and adjacent the first expandable clot engagement section; and
a second inner channel membrane positioned along the length of the inner channel proximal to and adjacent the second expandable clot engagement section, the second inner channel membrane being separated from the first inner channel membrane along a length of the inner channel,
wherein the stentriever comprises a collapsed configuration to be inserted into a microcatheter,
wherein the stentriever comprises an expanded configuration for exerting an outward radial force on the clot, and
wherein, when the stentriever is in the expanded configuration, the first expandable clot engagement section has a larger diameter than the inner channel, causing the aspiration to be directed from the first expandable clot engagement section by the first clot engagement membrane and into the first inner channel membrane.
13. The stentriever of claim 12 , wherein the distal engagement section comprises a plurality of distal clot cells capturing clot fragments.
14. The stentriever of claim 13 , wherein the distal engagement section comprises a distal membrane, and wherein the distal membrane comprises distal pores constricting flow of the aspiration into the distal engagement section.