Cyclopentane-based modulators of STING (stimulator of interferon genes)
Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.
1. A method of treating breast cancer in a mammal, the method comprising administering to the mammal a therapeutically effective amount of the compound:
or a pharmaceutically acceptable salt thereof.
2. The method of claim 1 , wherein said compound or salt is a component of an antibody-drug conjugate.
3. The method of claim 1 , wherein said compound or salt is a component of a particle-based delivery system.
4. The method of claim 1 , wherein the compound is
5. The method of claim 1 , wherein the compound is a pharmaceutically acceptable salt of
6. The method of claim 1 , wherein the compound is a single diastereoisomer of the compound
or a pharmaceutically acceptable salt thereof.