Tablets with improved acceptance and good storage stability
The present invention relates to tablets for animals, having improved acceptance and good storage stability.
1. A tablet comprising:
at least one active pharmaceutical ingredient,
from 31 to 40% by weight of meat flavouring,
at least 2% by weight of croscarmellose sodium, and from 8 to 20 wt. % starch or a starch derivative.
2. The tablet according to claim 1 , comprising from 3 to 8% by weight of croscarmellose sodium.
3. The tablet according to claim 1 , further comprising lactose.
4. The tablet according to claim 1 , wherein the at least one active pharmaceutical ingredient is selected from the group consisting of febantel, praziquantel and pyrantel.
5. The tablet according to claim 4 , comprising febantel, praziquantel and pyrantel as active ingredients.
6. The tablet according to claim 4 , wherein pyrantel is in the form of pyrantel embonate.
7. A method for controlling diseases or parasites in an animal in need thereof comprising orally administering a tablet of claim 1 to the animal.
8. The method according to claim 7 wherein the parasite is a helminth.
9. A method for preparing the tablet according to claim 1 , comprising
(a) mixing and granulating the active pharmaceutical ingredient(s) and optionally any further excipients;
(b) mixing and dry granulating the meat flavouring and optionally, further excipients, with the mixture from (a) to produce a homogenous mixture;
(c) adding any further excipients to the mixture produced in (b) to form a homogeneous compressible mixture, and
(d) processing the homogeneous compressible mixture.