IP Library Granted Patent US 11,147,764
Granted Patent B2
US 11,147,764 · App. 16/716,205 · Granted Oct 19, 2021

Tablets with improved acceptance and good storage stability

Inventors: Venkata-Rangarao Kanikanti (Leverkusen, DE); Hans-Juergen Hamann (Dormagen, DE); Georg Schulte (Wuppertal, DE); Patrick Billian (Leverkusen, DE)
Assignee: Elanco US, Inc.
A61K9/0056A61K9/2018A61K9/2054A61K9/2059A61K9/2095A61K31/216A61K31/27A61K31/4985A61K31/506A61K45/06
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Quick Facts
Patent No.
US 11,147,764
App. No.
16/716,205
Granted
Oct 19, 2021
Kind
B2
Abstract

The present invention relates to tablets for animals, having improved acceptance and good storage stability.

Claims (16)

1. A tablet comprising:

at least one active pharmaceutical ingredient,

from 31 to 40% by weight of meat flavouring,

at least 2% by weight of croscarmellose sodium, and from 8 to 20 wt. % starch or a starch derivative.

2. The tablet according to claim 1 , comprising from 3 to 8% by weight of croscarmellose sodium.

3. The tablet according to claim 1 , further comprising lactose.

4. The tablet according to claim 1 , wherein the at least one active pharmaceutical ingredient is selected from the group consisting of febantel, praziquantel and pyrantel.

5. The tablet according to claim 4 , comprising febantel, praziquantel and pyrantel as active ingredients.

6. The tablet according to claim 4 , wherein pyrantel is in the form of pyrantel embonate.

7. A method for controlling diseases or parasites in an animal in need thereof comprising orally administering a tablet of claim 1 to the animal.

8. The method according to claim 7 wherein the parasite is a helminth.

9. A method for preparing the tablet according to claim 1 , comprising

(a) mixing and granulating the active pharmaceutical ingredient(s) and optionally any further excipients;

(b) mixing and dry granulating the meat flavouring and optionally, further excipients, with the mixture from (a) to produce a homogenous mixture;

(c) adding any further excipients to the mixture produced in (b) to form a homogeneous compressible mixture, and

(d) processing the homogeneous compressible mixture.

Assignments (2)
CHANGE OF NAME Recorded Feb 8, 2024
From: BAYER ANIMAL HEALTH GMBH
To: ELANCO ANIMAL HEALTH GMBH
Reel/Frame 066525/0898 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 16, 2019
From: KANIKANTI, VENKATA-RANGARAO; HAMANN, HANS-JUERGEN; SCHULTE, GEORG; BILLIAN, PATRICK
To: BAYER ANIMAL HEALTH GMBH
Reel/Frame 051298/0208 →