PLANT EXTRACT FROM LOW-THC CANNABIS FOR THE TREATMENT OF DISEASE
The present invention relates to a plant extract from a low-tetrahydrocannabinol (THC) variety of Cannabis sativa subsp. sativa for the treatment of disease. The invention further relates to the production of the extract and pharmaceutical compositions comprising said extract and the uses thereof.
1 . Plant extract from the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds of a low-tetrahydrocannabinol (THC) variety of Cannabis sativa subspecies sativa for the treatment of diseases.
2 . Plant extract according to claim 1 , wherein solvents and/or mixtures of solvents are used as the extraction medium, the solvents being selected from the group comprising water, table salt solution, low-molecular-weight alcohols, acetone, esters, and ethers.
3 . Plant extract according to claim 2 , wherein, 0.9% table salt solution, 90% ethanol, or 70% isopropanol is used as the extraction medium.
4 . Plant extract according to claim 1 , wherein the low-THC variety of Cannabis sativa subspecies sativa is the variety Futura 75.
5 . Plant extract according to claim 1 , wherein the THC content is less than 2% (wt.-%) THC content.
6 . Method for the production of a plant extract from the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds of a low-tetrahydrocannabinol (THC) variety of Cannabis sativa subspecies sativa , comprising the steps of
a) drying the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds,
b) pulverizing the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds, and
c) extracting the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds.
7 . Method according to claim 6 , wherein the extraction in c) comprises the steps of
c-1) admixing the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds for 24 hours-48 hours with an extraction medium at room temperature, and
c-2) filtering the extract.
8 . Method according to claim 6 , further comprising the step of
d) freeze-drying of the acquired extract or
e) vacuum extraction of the acquired extract.
9 . Method according to claim 6 , wherein solvents and/or mixtures of solvents are used as the extraction medium, the solvents being selected from the group comprising water, table salt solution, low-molecular-weight alcohols, acetone, esters, and ethers.
10 . Method according to claim 9 , wherein 0.9% table salt solution, 90% ethanol, or 70% isopropanol is used as the extraction medium.
11 . Method according to claim 6 , wherein the low-THC variety of Cannabis sativa subspecies sativa is preferably the variety Futura 75.
12 . Pharmaceutical, cosmetic or dermatological composition, comprising a plant extract made of the flowers and/or flower-proximal leaves and/or stalks and/or roots and/or seeds of one and/or multiple low-THC varieties of Cannabis sativa subspecies sativa , produced according to the method of claim 6 , and further pharmaceutically suitable aids and/or additives.
13 . (canceled)
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17 . Plant extract according to claim 1 , wherein the THC content is less than 0.5 to 0.2% or as low as 0.1 or 0% (wt.-%) THC content