IP Library Granted Patent US 11,504,682
Granted Patent B2
US 11,504,682 · App. 16/724,539 · Granted Nov 22, 2022

Mixer base assembly for mixing vessels and method of use

Inventors: Eric A. Corti (Worcester, MA); Timothy Keating (Cambridge, GB); Andrew J. Malloy (Hertfordshire, GB)
Assignee: Pall Corporation
B01F33/452B01F35/2132B01F35/2133
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Quick Facts
Patent No.
US 11,504,682
App. No.
16/724,539
Granted
Nov 22, 2022
Kind
B2
Abstract

A mixer base assembly comprises (a) a body having an upper end including a mating face for mixing vessel connection; a lower end including a cavity; a first side wall, a second side wall, a third side wall, and a fourth side wall; an inlet port arranged in the first side wall; an outlet port arranged in the third side wall; a sampling port arranged in the fourth side wall; a probe port arranged in the third side wall; and, a fluid mixing chamber including a baffle and having a bottom wall; (b) an impeller seat arranged in the cavity in the lower end of the body; and, (c) a levitating magnetic impeller arranged in the impeller seat, the impeller comprising a magnet, a base, and at least two blades, wherein the blades extend above the bottom wall of the fluid mixing chamber into the fluid mixing chamber.

Claims (34)

1. A mixer base assembly comprising:

(a) a body having:

(i) an upper end including a mating face for mixing vessel connection;

(ii) a lower end including a cavity;

(iii) a plurality of side walls comprising a first side wall, a second side wall, a third side wall, and a fourth side wall;

(iv) an inlet port arranged in the first side wall;

(v) an outlet port arranged in the third side wall;

(vi) a sampling port arranged in the fourth side wall;

(vii) at least one probe port arranged in the third side wall; and,

(viii) a fluid mixing chamber including a baffle, the fluid mixing chamber having a bottom wall;

(b) an impeller seat arranged in the cavity in the lower end of the body; and,

(c) a levitating magnetic impeller arranged in the impeller seat, the levitating magnetic impeller comprising a magnet, a base, and at least two blades, wherein the at least two blades extend above the bottom wall of the fluid mixing chamber into the fluid mixing chamber.

2. The mixer base assembly of claim 1 , further comprising a vent inlet port and a vent outlet port, wherein the vent outlet port is arranged in the first side wall of the body.

3. The mixer base assembly of claim 2 , wherein the bottom wall of the mixing chamber slopes downwardly in a direction from the inlet port toward the outlet port.

4. The mixer base assembly of claim 3 , further comprising at least one probe insertable into the at least one probe port.

5. The mixer base assembly of claim 3 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

6. The mixer base assembly of claim 2 , further comprising at least one probe insertable into the at least one probe port.

7. The mixer base assembly of claim 6 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

8. The mixer base assembly of claim 2 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

9. The mixer base assembly of claim 1 , wherein the bottom wall of the mixing chamber slopes downwardly in a direction from the inlet port toward the outlet port.

10. The mixer base assembly of claim 9 , further comprising at least one probe insertable into the at least one probe port.

11. The mixer base assembly of claim 10 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

12. The mixer base assembly of claim 9 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

13. The mixer base assembly of claim 1 , further comprising at least one probe insertable into the at least one probe port.

14. The mixer base assembly of claim 13 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

15. The mixer base assembly of claim 1 , further comprising a sampling arrangement comprising a sample port plug and a sample port nut, wherein the sample port plug is insertable into the sampling port.

16. The mixer base assembly of claim 1 , wherein the base of the levitating magnetic impeller includes a central vertical opening for a spindle, the mixer base assembly further comprising an interface plate arranged in the cavity in the lower end of the body, the interface plate including the spindle, wherein the levitating magnetic impeller rotates around the spindle.

17. A method for mixing fluid, the method comprising:

connecting a mixing vessel to a mixer base assembly comprising (a) a body having (i) an upper end including a mating face for mixing vessel connection; (ii) a lower end including a cavity; (iii) a plurality of side walls comprising a first side wall, a second side wall, a third side wall, and a fourth side wall; (iv) an inlet port arranged in the first side wall; (v) an outlet port arranged in the third side wall; (vi) a sampling port arranged in the fourth side wall; (vii) at least one probe port arranged in the third side wall; and, (viii) a fluid mixing chamber including a baffle, the fluid mixing chamber having a bottom wall; (b) an impeller seat arranged in the cavity in the lower end of the body; and, (c) a levitating magnetic impeller arranged in the impeller seat, the levitating magnetic impeller comprising a magnet, a base, and at least two blades, wherein the at least two blades extend above the bottom wall of the fluid mixing chamber into the fluid mixing chamber; and,

introducing fluid into the fluid mixing chamber, and rotating the levitating magnetic impeller to mix the fluid in the fluid mixing chamber.

18. The method of claim 17 , further comprising measuring the pH and/or conductivity of the fluid in the fluid mixing chamber.

19. The method of claim 18 , further comprising sampling the fluid in the fluid mixing chamber.

20. The method of claim 17 , further comprising sampling the fluid in the fluid mixing chamber.

21. The method of claim 17 , wherein the base of the levitating magnetic impeller includes a central vertical opening for a spindle, the mixer base assembly further comprising an interface plate arranged in the cavity in the lower end of the body, the interface plate including the spindle, wherein the levitating magnetic impeller rotates around the spindle.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 22, 2023
From: PALL CORPORATION
To: CYTIVA US LLC
Reel/Frame 063144/0716 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2020
From: CORTI, ERIC A.; KEATING, TIMOTHY; MALLOY, ANDREW J.
To: PALL CORPORATION
Reel/Frame 051580/0980 →
Continuity (1)
Related Publication 20210187456A1 · Jun 24, 2021