IP Library Granted Patent US 11,168,046
Granted Patent B2
US 11,168,046 · App. 16/739,645 · Granted Nov 9, 2021

1,3-fatty diol compounds and derivatives thereof

Inventor: Haibo Wang (San Pablo, CA)
Assignee: Genomatica, Inc.
C07C33/035C07H15/10
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Quick Facts
Patent No.
US 11,168,046
App. No.
16/739,645
Granted
Nov 9, 2021
Kind
B2
Abstract

The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds and derivatives thereof which are useful e.g., in the production of personal care products, surfactants, detergents, polymers, paints, coatings, and as emulsifiers, emollients, and thickeners in cosmetics and foods, as industrial solvents and plasticizers, etc.

Claims (18)

1. A compound having a structure according to Formula V

stereoisomers thereof, and pharmaceutical salts thereof, wherein R 1 and R 2 are independently selected from the group consisting of H, a monosaccharide, a disaccharide, a trisaccharide, and a polysaccharide, wherein each of the monosaccharide, disaccharide, trisaccharide or polysaccharide is bound at an anomeric carbon; and wherein R 1 and R 2 are not both H; and

n is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 or 14.

2. The compound of claim 1 , wherein n is 1 or 5.

3. The compound of claim 1 , wherein the double bond is in (Z) configuration.

4. The compound of claim 3 , wherein the chiral center at C-3 has an R configuration.

5. The compound of claim 1 , wherein the monosaccharide, disaccharide, trisaccharide, or polysaccharide is bound at the anomeric carbon via an α-glycosidic bond.

6. The compound of claim 1 , wherein neither R 1 nor R 2 are H.

7. The compound of claim 1 , wherein R 1 and R 2 are different monosaccharides.

8. The compound of claim 1 , wherein R 1 and R 2 are the same monosaccharide.

9. The compound of claim 1 , wherein the monosaccharide is a pentose sugar or a hexose sugar.

10. The compound of claim 9 , wherein the monosaccharide is a hexose sugar selected from the group consisting of allose, altrose, glucose, mannose, gulose, iodose, galactose and talose.

11. The compound of claim 10 , wherein the monosaccharide is glucose.

12. The compound of claim 1 , wherein R 1 is glucose.

13. The compound of claim 1 , wherein the disaccharide, trisaccharide, or polysaccharide comprises a pentose sugar, a hexose sugar, or a mixture thereof.

14. The compound of claim 13 , wherein the disaccharide, trisaccharide, or polysaccharide comprises a hexose sugar selected from the group consisting of allose, altrose, glucose, mannose, gulose, iodose, galactose, talose, and a mixture of any two or more thereof.

15. The compound of claim 1 , wherein R 1 is maltose or isomaltose.

16. A composition comprising the compound of claim 1 , wherein the composition is selected from the group consisting of a personal care product, a pharmaceutical, a food product, and an agricultural formulation.

Assignments (6)
SECURITY INTEREST Recorded Feb 10, 2026
From: GENOMATICA, INC.
To: AGAIN BIO APS
Reel/Frame 074708/0001 →
SECURITY INTEREST Recorded Dec 9, 2025
From: GENOMATICA, INC.
To: NOVO HOLDINGS A/S, AS COLLATERAL AGENT
Reel/Frame 073915/0027 →
SECURITY INTEREST Recorded Jun 2, 2025
From: GENOMATICA, INC.
To: OXFORD FINANCE LLC
Reel/Frame 071471/0770 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 22, 2024
From: BOND, RISHA LINDIG
To: GENOMATICA, INC.
Reel/Frame 068964/0464 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2021
From: WANG, HAIBO
To: REG LIFE SCIENCES, LLC
Reel/Frame 056879/0354 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2021
From: REG LIFE SCIENCES, LLC
To: GENOMATICA, INC.
Reel/Frame 056893/0320 →