IP Library › Granted Patent US 12,268,587
Granted Patent B2
US 12,268,587 · App. 16/742,662 · Granted Apr 8, 2025

Intra vascular guidewire filter system for pulmonary embolism protection and embolism removal or maceration

Inventors: Samuel Morrison (Eden Prairie, MN); Chad Stark (Eden Prairie, MN)
Assignee: Surmodics MD, LLC
A61F2/013A61B17/22012A61B17/22032A61B17/221A61F2/012A61B2017/00778A61B2017/00867A61B2017/22001A61B2017/22035A61B2017/22038A61B2017/22042A61B2017/22054A61B2017/2212A61F2/011A61F2002/016A61F2210/0014A61F2210/0057A61F2210/0061A61F2230/0008A61F2230/0069A61F2230/008A61F2230/0086A61F2230/0093A61F2230/0097A61F2250/0036A61F2250/004A61F2250/0042
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Quick Facts
Patent No.
US 12,268,587
App. No.
16/742,662
Granted
Apr 8, 2025
Kind
B2
Abstract

An intravascular emboli capture and retrieval system for intravascular embolism protection and embolism removal or maceration. Guidewire mounted proximally and distally located multiple opening filters are deployed within the vasculature and used to part, divide and macerate embolic debris and to capture such embolic debris within the confines thereof. A deployable flexible preformed memory shaped capture sleeve is alternatively used to collapse one or more filters and embolic debris therein for subsequent proximal withdrawal from the vasculature.

Claims (74)

1. A catheter assembly comprising:

a guidewire extending from a guidewire proximal portion to a guidewire distal portion;

first and second self-expanding deployable filters coupled with the guidewire, each of the first and second deployable filters include:

a proximal filter end, and a distal filter end, wherein one of the proximal or distal filter ends is slidably coupled along the guidewire and the other of the proximal or distal filter ends is fixed to the guidewire; and

component strands extending between the proximal and distal filter ends;

wherein the first and second deployable filters include respective first and second filter strand profiles including the respective component strands, and the first filter strand profile is statically misaligned relative to the second filter strand profile according to fixing of the one of the proximal or distal filter ends to the guidewire;

wherein the first and second deployable filters each have a cylindrical shape having proximal, distal and medial cylindrical portions;

wherein at least one of the first or second deployable filters include at least first, second and third imaging markers, wherein:

the first imaging marker is coupled at the proximal cylindrical portion of the cylindrical shape of the first or second deployable filters;

the second imaging marker is coupled at the medial cylindrical portion of the cylindrical shape of the first or second deployable filters; and

the third imaging marker is coupled at the distal cylindrical portion of the cylindrical shape of the first or second deployable filters, and at least two of the first, second or third imaging markers are unobscured in any orientation of the respective deployable filter in a deployed configuration; and

a capture sleeve catheter movably coupled along the guidewire, the capture sleeve catheter includes:

a positioning tube extending from a tube proximal portion to a tube distal portion, and the guidewire is slidably received within the positioning tube;

a capture sleeve coupled with the tube distal portion;

wherein the capture sleeve includes a tapered proximal section and a cylindrical barrel extending distally from the tapered proximal section, and in a deployed capture sleeve configuration the cylindrical barrel is configured to conform to a vessel profile between the tapered proximal section and a capture sleeve distal tip; and

wherein the capture sleeve includes first and second stacked layers of braided filaments, and the first stacked layer extends from the tapered proximal section to an elbow proximate the capture sleeve distal tip, and the second stacked layer extends from the elbow toward the tapered proximal section.

2. The catheter assembly of claim 1 , further comprising a delivery sheath configured to transition the first and second deployable filters between compressed and deployed configurations, and wherein in the deployed configuration the delivery sheath is withdrawn and the first and second deployable filters self-expand.

3. The catheter assembly of claim 2 , wherein the first and second strand profiles are misaligned at least in the deployed configuration.

4. The catheter assembly of claim 1 , wherein misalignment of the first and second filter strand profiles includes the first deployable filter rotationally offset from the second deployable filter and statically fixing the one of the proximal or distal filter ends to the guidewire is configured to maintain the rotational offset between the first deployable filter and the second deployable filter.

5. The catheter assembly of claim 1 , wherein:

the second imaging marker and the third imaging marker are observable from a first orientation; and

the guidewire obscures the first imaging marker and the first imaging marker is unobservable in the first orientation.

6. The catheter assembly of claim 5 , wherein:

the first imaging marker and the third imaging marker are observable from a second orientation;

the guidewire obscures the second imaging marker and the second imaging marker is unobservable from the second orientation.

7. The catheter assembly of claim 1 , wherein at least one of the first, second, and third imaging markers are obscured in any orientation of the respective deployable filter in a compressed configuration.

8. A catheter assembly comprising:

a guidewire extending from a guidewire proximal portion to a guidewire distal portion;

one or more deployable filters coupled with the guidewire, the one or more deployable filters includes:

a proximal filter end, and a distal filter end, wherein at least one of the proximal or distal filter ends is movably coupled along the guidewire; and

component strands extending between the proximal and distal filter ends; and

a capture sleeve catheter movably coupled along the guidewire, the capture sleeve catheter includes:

a positioning tube extending from a tube proximal portion to a tube distal portion, and the guidewire is slidably received within the positioning tube;

a capture sleeve coupled with the tube distal portion;

wherein the capture sleeve includes a tapered proximal section and a cylindrical barrel extending distally from the tapered proximal section, and in a deployed capture sleeve configuration the cylindrical barrel is configured to conform to a vessel profile between the tapered proximal section and a capture sleeve distal tip; and

wherein the capture sleeve includes first and second stacked layers of braided filaments, and the first stacked layer extends from the tapered proximal section to an elbow proximate the capture sleeve distal tip, and the second stacked layer extends from the elbow toward the tapered proximal section.

9. The catheter assembly of claim 8 , wherein the capture sleeve includes braided filaments.

10. The catheter assembly of claim 9 , wherein the braided filaments are coupled at the tapered proximal portion with one or more of a chemical bond or a mechanical bond.

11. The catheter assembly of claim 8 , wherein the capture sleeve is sized and shaped to receive a portion of the one or more deployable filters when the capture sleeve is deployed and the one or more deployable filters are deployed.

12. The catheter assembly of claim 8 , wherein:

the capture sleeve includes a sleeve profile;

each of the one or more deployable filters include a filter profile;

the sleeve profile corresponds with the filter profile to allow the capture sleeve to receive a portion of one or more of the one or more deployable filters.

13. The catheter assembly of claim 12 , wherein the sleeve profile corresponds with the filter profile to allow the capture sleeve to receive the entirety of the one or more deployable filters.

14. The catheter assembly of claim 8 , wherein the cylindrical barrel has a constant outer dimension to improve the conformance of the cylindrical barrel with the to the vessel profile.

15. The catheter assembly of claim 8 , further comprising a delivery catheter sized and shaped to receive the capture sleeve catheter.

16. A catheter assembly comprising:

a guidewire extending from a guidewire proximal portion to a guidewire distal portion;

one or more self-expanding deployable filters coupled with the guidewire, each of the one or more deployable filters includes:

a proximal filter end, and a distal filter end, wherein one of the proximal or distal filter ends is slidably coupled along the guidewire and the other of the proximal or distal filter ends is fixed to the guidewire;

component strands extending between the proximal and distal filter ends; and

wherein the first and second deployable filters include respective first and second filter strand profiles including the respective component strands, and the first filter strand profile is statically misaligned relative to the second filter strand profile according to fixing of the one of the proximal or distal filter ends to the guidewire;

wherein the first and second deployable filters each have a cylindrical shape having proximal, distal, and medial cylindrical portions;

wherein at least one of the first or second deployable filters include at least first, second and third imaging markers, wherein:

the first imaging marker is coupled at the proximal cylindrical portion of the first or second deployable filters;

the second imaging marker is coupled at the medial cylindrical portion of the first or second deployable filters; and

the third imaging marker is coupled at a distal location along the cylindrical profile of the first or second deployable filters, and at least two of the first, second or third imaging markers are unobscured in any orientation of the respective deployable filter in a deployed configuration;

a filter delivery catheter configured for movable coupling along the guidewire, the filter delivery catheter includes:

a filter delivery operator including a hub having an interior socket, wherein the interior socket includes:

a proximal section having a first dimension; and

a distal section having a second dimension smaller than the first dimension; and

a filter delivery tube extending from the filter delivery operator to a filter delivery tube distal portion;

an installation brace configured for reception with the interior socket, the installation brace includes a brace wall surrounding a filter cavity, wherein the installation brace is configured to:

retain the one or more deployable filters in a compressed configuration;

align the one or more deployable filters with the distal section; and

deliver the one or more deployable filters in the compressed configuration to the distal section of the filter delivery operator; and

a capture sleeve catheter movably coupled along the guidewire, the capture sleeve catheter includes:

a positioning tube extending from a tube proximal portion to a tube distal portion, and the guidewire is slidably received within the positioning tube;

a capture sleeve coupled with the tube distal portion;

wherein the capture sleeve includes a tapered proximal section and a cylindrical barrel extending distally from the tapered proximal section, and in a deployed capture sleeve configuration the cylindrical barrel is configured to conform to a vessel profile between the tapered proximal section and a capture sleeve distal tip; and

wherein the capture sleeve includes first and second stacked layers of braided filaments, and the first stacked layer extends from the tapered proximal section to an elbow proximate the capture sleeve distal tip, and the second stacked layer extends from the elbow toward the tapered proximal section.

17. The catheter assembly of claim 16 , wherein the installation brace facilitates installation of the guidewire and the one or more deployable filters into the filter delivery tube of the filter delivery catheter.

18. The catheter assembly of claim 16 , wherein the installation brace is separable from the interior socket when the guidewire and the one or more deployable filters are installed in the filter delivery tube of the filter delivery catheter.

19. The catheter assembly of claim 16 , wherein the one or more deployable filters include first and second deployable filters, and the first and second deployable filters include respective first and second filter strand profiles including the respective component strands, and the first filter strand profile is misaligned relative to the second filter strand profile.

Assignments (5)
PARTIAL RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT R/F 074461/0199 Recorded May 18, 2026
From: BANK OF MONTREAL, AS COLLATERAL AGENT
To: SURMODICS MD, LLC
Reel/Frame 075578/0955 →
RELEASE OF SECURITY INTEREST Recorded Nov 24, 2025
From: MIDCAP FUNDING IV TRUST
To: SURMODICS, INC.; SURMODICS SHARED SERVICES, LLC; SURMODICS HOLDINGS, LLC; SURMODICS COATINGS, LLC; SURMODICS MD, LLC; SURMODICS COATINGS MFG, LLC; SURMODICS IVD, INC.; SURMODICS MD OPERATIONS, LLC; NORMEDIX, INC.
Reel/Frame 073690/0186 →
SECURITY INTEREST Recorded Aug 23, 2024
From: SURMODICS, INC.; SURMODICS SHARED SERVICES, LLC; SURMODICS HOLDINGS, LLC; SURMODICS COATINGS, LLC; SURMODICS MD, LLC; SURMODICS COATINGS MFG, LLC; SURMODICS IVD, INC.; SURMODICS MD OPERATIONS, LLC; NORMEDIX, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 068762/0423 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 052199 FRAME: 0569. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT . Recorded Jan 13, 2021
From: MORRISON, SAMUEL; STARK, CHAD
To: SURMODICS MD, LLC
Reel/Frame 054975/0583 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2020
From: MORRISON, SAMUEL; STARK, CHAD
To: SURMODICS, INC.
Reel/Frame 052199/0569 →
Continuity (4)
Continuation In Part 15093916 · Apr 8, 2016
Continuation 12738702
Provisional Application 61000465 · Oct 26, 2007
Related Publication 20200155293A1 · May 21, 2020
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