IP Library Granted Patent US 11,458,289
Granted Patent B2
US 11,458,289 · App. 16/754,881 · Granted Oct 4, 2022

Applicator for applying a microneedle array to skin

Inventors: Craig S. Moeckly (White Bear Lake, MN); Michael J. Frits (Lake Elmo, MN); Steven P. Gowers (Cambridge, GB); Gregory R. Ley (Blaine, MN); Richard R. Mathias (Brookline, MA); Robert G. M. Selby (Hertfordshire, GB); Ryan Patrick Simmers (Fargo, MN); Michael B. Sivigny (Lake Elmo, MN); Daniel G. T. Strange (Cambridge, GB)
Assignee: Kindeva Drug Delivery L.P.
A61M37/0015A61M2037/0023A61M2205/584A61M2210/04
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Quick Facts
Patent No.
US 11,458,289
App. No.
16/754,881
Granted
Oct 4, 2022
Kind
B2
Abstract

An applicator and method for applying a microneedle array to skin. The applicator can include a body having a first portion and a second portion defining a cavity, the second portion having a slot presented on an outside surface for insertion of the microneedle array into the cavity. The first portion and the second portion are slidable relative to one other along an axis enabling the body to be in an unprimed configuration and a primed configuration. The applicator further includes a door operable with the second portion, the door being movable from a first door position to a second door position, wherein when the device is in the unprimed configuration, the door at least partially obstructs the slot and access into the cavity. When the device is in the primed configuration, the door does not obstruct the slots and enables access into the cavity.

Claims (13)

1. A device for applying a microneedle array to a surface, said device comprising:

a body comprising a first portion and a second portion defining a cavity, said second portion comprising a slot presented on an outside surface of said second portion for insertion of the microneedle array into said cavity, said first portion and said second portion slidable relative to one other along an axis thus enabling said device to be in an unprimed configuration and a primed configuration; and

a plunger disposed in said cavity, said plunger comprising a first plunger end and a second plunger end, said plunger movable from a first position when said device is in said unprimed configuration to a second position when said device is in said primed configuration, and

a microneedle array;

wherein when said device is in said primed configuration, the microneedle array is adapted to be inserted into said cavity through said slot and positioned proximate said second plunger end, and further wherein the plunger is adapted to contact the microneedle array when the device is in the primed configuration and the first portion and the second portion of the body are axially compressed but before the plunger is released.

2. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are in contact with one another when the plunger is in the second position but before the first and second portions of the body are axially compressed.

3. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are less than about 2 mm from one another when the plunger is in the second position but before the first and second portions of the body are axially compressed.

4. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are less than about 1 mm from one when the plunger is in the second position but before the first and second portions of the body are axially compressed.

5. The device of claim 1 , wherein after the microneedle array is inserted in said slot and positioned proximate said second plunger end, the microneedle array and said second plunger end are less than about 0.5 mm from one another when the plunger is in the second position but before the first and second portions of the body are axially compressed.

6. The device of claim 1 , wherein said second portion comprises an inner surface comprising a low surface energy material, wherein when said plunger moves from said first position to said second position, any friction between the microneedle array and said inner surface, should they be in slidable engagement with one another, is minimized.

7. The device of claim 1 , further comprising a biasing member for biasing said plunger to said first position when said device is in said unprimed configuration.

8. The device of claim 7 , wherein said biasing member comprises a compression spring and wherein said compression spring is compressed and energized when said plunger is in said second position when said device is in said primed configuration.

9. The device of claim 1 , further comprising visual indicia proximate the slot identifying a location of the slot to a user.

Assignments (5)
SECURITY INTEREST Recorded Dec 14, 2022
From: KINDEVA DRUG DELIVERY L.P.
To: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
Reel/Frame 062122/0618 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENT COLLATERAL RECORDED AT R/F 053586/0715 Recorded Dec 12, 2022
From: MIDCAP FINANCIAL TRUST, AS ADMINISTRATIVE AGENT
To: KINDEVA DRUG DELIVERY L.P.
Reel/Frame 062115/0707 →
SECURITY INTEREST Recorded Aug 24, 2020
From: KINDEVA DRUG DELIVERY L.P.
To: MIDCAP FINANCIAL TRUST, AS ADMINISTRATIVE AGENT
Reel/Frame 053586/0715 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 2, 2020
From: 3M COMPANY; 3M INNOVATIVE PROPERTIES COMPANY
To: KINDEVA DRUG DELIVERY L.P.
Reel/Frame 052818/0234 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2020
From: MOECKLY, CRAIG S.; FRITS, MICHAEL J.; GOWERS, STEVEN P.; LEY, GREGORY R.; MATHIAS, RICHARD R.; SELBY, ROBERT G. M.; SIMMERS, RYAN PATRICK; SIVIGNY, MICHAEL B.; STRANGE, DANIEL G. T.
To: 3M INNOVATIVE PROPERTIES COMPANY
Reel/Frame 052355/0101 →