Microbiocidal thiazole derivatives

1. A compound of formula (I):

wherein,

R 1 is fluoro;

R 2 is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkyl, or C 3 -C 4 cycloalkyl;

R 3 is halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, C 1 -C 4 haloalkyl, or C 3 -C 4 cycloalkyl;

R 4 is hydrogen;

R 5 is hydrogen, halogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 4 haloalkyl, C 2 -C 6 haloalkenyl, C 2 -C 6 haloalkynyl, hydroxyC 1 -C 4 alkyl, cyanoC 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, phenyl or heteroaryl, wherein the heteroaryl moiety is a 5- or 6-membered aromatic monocyclic ring comprising 1, 2, 3 or 4 heteroatoms individually selected from nitrogen, oxygen and sulfur, and wherein the C 3 -C 6 cycloalkyl, phenyl and heteroaryl moieties are each optionally substituted with 1 to 3 groups represented by R 7 ;

R 6 is hydrogen, halogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 4 haloalkyl, C 2 -C 6 haloalkenyl, C 2 -C 6 haloalkynyl, hydroxyC 1 -C 4 alkyl, cyanoC 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, phenyl or heteroaryl, wherein the heteroaryl moiety is a 5- or 6-membered aromatic monocyclic ring comprising 1, 2, 3 or 4 heteroatoms individually selected from nitrogen, oxygen and sulfur, and wherein the C 3 -C 6 cycloalkyl, phenyl and heteroaryl moieties are each optionally substituted with 1 to 3 groups represented by R 7 ;

R 7 is halogen, cyano, hydroxyl, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, or C 3 -C 4 cycloalkyl;

X is N;

or a salt or an N-oxide thereof.

2. The compound according to claim 1 , wherein R 2 is hydrogen, methyl, ethyl, methoxy or ethoxy.

3. The compound according to claim 1 , wherein R 3 is halogen or C 1 -C 3 alkyl.

4. The compound according to claim 1 , wherein R 5 is hydrogen, halogen, C 1 -C 6 alkyl, C 2 -C 6 alkynyl, C 3 -C 4 cycloalkyl, or phenyl, wherein the C 3 -C 4 cycloalkyl and phenyl moieties are each optionally substituted with 1 to 3 groups represented by R 7 .

5. The compound according to claim 1 , wherein R 6 is hydrogen, halogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, or phenyl, wherein the heteroaryl moiety is a 5- or 6-membered aromatic monocyclic ring comprising 1, 2, or 3 heteroatoms individually selected from nitrogen, oxygen and sulfur, and wherein the C 3 -C 6 cycloalkyl, phenyl and heteroaryl moieties are optionally substituted with 1 to 3 groups represented by R 7 .

6. The compound according to claim 1 , wherein the compound of formula (I) is 2-[(2,6-difluoro-4-pyridyl)amino]-5-methyl-N(2-methylcyclobutyl)thiazole-4-carboxamide, 2-[(2,6-difluoro-4-pyridyl)amino]-N-(2-ethylcyclobutyl)-5-methyl-thiazole-4-carboxamide, N-(2,2-difluorocyclobutyl)-2-[(2,6-difluoro-4-pyridyl)amino]-5-methyl-thiazole-4-carboxamide, 2-[(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide, or N-(2,2-diethylcyclobutyl)-2-[(2,6-difluoro-4-pyridyl)amino]-5-methyl-thiazole-4-carboxamide.

7. An agrochemical composition comprising a fungicidally effective amount of a compound of formula (I) according to claim 1 .

8. The composition according to claim 7 , further comprising at least one additional active ingredient and/or an agrochemically-acceptable diluent or carrier.

9. A method of controlling or preventing infestation of useful plants by phytopathogenic microorganisms, wherein a fungicidally effective amount of a compound of formula (I) according to claim 1 , or a composition comprising this compound as active ingredient, is applied to the plants, to parts thereof or the locus thereof.

10. The compound according to claim 1 , wherein R 6 is halogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 4 haloalkyl, C 2 -C 6 haloalkenyl, C 2 -C 6 haloalkynyl, hydroxyC 1 -C 4 alkyl, cyanoC 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, phenyl or heteroaryl, wherein the heteroaryl moiety is a 5- or 6-membered aromatic monocyclic ring comprising 1, 2, 3 or 4 heteroatoms individually selected from nitrogen, oxygen and sulfur, and wherein the C 3 -C 6 cycloalkyl, phenyl and heteroaryl moieties are each optionally substituted with 1 to 3 groups represented by R 7 .

11. The compound according to claim 6 , wherein the compound is 2-[(2,6-difluoro-4-pyridyl)amino]-5-methyl-N-(2-methylcyclobutyl)thiazole-4-carboxamide.

12. The compound according to claim 6 , wherein the compound is 2-[(2,6-difluoro-4-pyridyl)amino]-N-(2-ethylcyclobutyl)-5-methyl-thiazole-4-carboxamide.

13. The compound according to claim 6 , wherein the compound is N-(2,2-difluorocyclobutyl)-2-[(2,6-difluoro-4-pyridyl)amino]-5-methyl-thiazole-4-carboxamide.

14. The compound according to claim 6 , wherein the compound is 2-[(2,6-difluoro-4-pyridyl)amino]-N-(2,2-dimethylcyclobutyl)-5-methyl-thiazole-4-carboxamide.

15. The compound according to claim 6 , wherein the compound is N-(2,2-diethylcyclobutyl)-2-[(2,6-difluoro-4-pyridyl)amino]-5-methyl-thiazole-4-carboxamide.

16. A method of controlling phytopathogenic microorganisms, comprising: contacting phytopathogenic microorganisms with a compound of formula (I) according to claim 1 .

17. The method according to claim 16 , wherein the compound of formula (I) is selected from