Wound dressing sealant and use thereof
Embodiments disclosed herein are directed to sealing compositions for negative pressure treatment systems and wound dressing systems, devices containing the same, apparatuses, uses and methods for creating a main wound dressing portion for use in wound care, more particularly for sealing a trimmable dressing, having a main dressing portion or cell in fluid (e.g., gas) communication with additional dressing portions or cells, for use in woundcare, more particularly that may be used for the treatment of wounds. In particular, some embodiments are directed to compositions for improving the versatility of wound dressings for wounds of different shapes or sizes.
1. A method of treating a wound, comprising:
providing a wound dressing comprising:
a backing layer; and
one or more transmission layers positioned beneath the backing layer;
removing a portion of the wound dressing to create a main wound dressing portion with one or more exposed portions, wherein the one or more transmission layers is exposed at the one or more exposed portions;
positioning the main wound dressing portion over a wound;
sealing the main wound dressing portion to skin surrounding the wound;
dispensing a composition comprising a silicone curing system to a location at or within the one or more exposed portions of the main wound dressing portion thereby sealing the one or more exposed portions; and
wherein the composition is shear thinning or shape conforming when subject to load such that the viscosity of the composition is reduced when the composition is subject to shear forces during dispensing, the composition having viscosity in the range of 10 to 100 Pa·s.
2. The method of claim 1 , wherein dispensing the composition comprises internally impregnating the one or more transmission layers at the one or more exposed portions.
3. The method of claim 2 , further comprising impregnating the one or more transmission layers to a distance in the range of 0.2 to 25 mm within the one or more transmission layers.
4. The method of claim 1 , further comprising applying negative pressure to the wound through the backing layer of the main wound dressing portion.
5. The method of claim 4 , further comprising drawing the dispensable composition up to 25 mm within the one or more transmission layers at the one or more exposed portions via the negative pressure.
6. The method of claim 4 , wherein the wound dressing exhibits no change or substantially no change in compressibility at the location of the seal on initiation of the negative pressure.
7. The method of claim 4 , further comprising dispensing the dispensable composition with formation of an air-tight elastomer which is capable of containing the negative pressure.
8. The method of claim 1 , wherein the dispensable composition has a viscosity in the range of 11 and 14 Pa·s.
9. The method of claim 1 , wherein the dispensable composition, when cured, is conformable.
10. The method of claim 1 , further comprising subjecting the dispensable composition to shear forces during application to the one or more exposed portions, wherein the dispensable composition reduces viscosity when subjected to the shear forces.
11. The method of claim 1 , wherein the dispensable composition has a curing time at 23° C. in the range from 0.5 to 5 min.
12. The method of claim 1 , wherein the dispensable composition has a curing time at 32° C. in the range from 0.5 to 7 min.
13. The method of claim 1 , further comprising dispensing the dispensable composition directly at the exposed portion through an exposed face of the one or more transmission layers.
14. The method of claim 4 , further comprising applying negative pressure to the main wound dressing after sealing the one or more exposed portions.
15. The method of claim 1 , wherein the composition does not flow from the location.
16. The method of claim 1 , wherein the composition is configured to be drawn into the transmission layer by negative pressure prior to curing.
17. The method of claim 1 , wherein the silicone curing system comprises two or more components, the silicone curing system exhibiting zero or low tack for 0.5 to 25 minutes after mixing of the two or more components.