IP Library Granted Patent US 11,656,228
Granted Patent B2
US 11,656,228 · App. 16/779,974 · Granted May 23, 2023

Compositions for use in mycotoxin extraction

Inventors: Ronald W. Sarver, Jr. (Dexter, MI); Ronald D. Beaubien, Jr. (Jackson, MI); Nanduri Viswaprakash (Dewitt, MI)
Assignee: NEOGEN CORPORATION
G01N33/56961A23L5/23A23L5/27A23L5/273A23L11/32A23L11/34A23V2002/00G01N2333/37G01N2469/10
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Quick Facts
Patent No.
US 11,656,228
App. No.
16/779,974
Granted
May 23, 2023
Kind
B2
Abstract

The present invention relates to aqueous compositions comprising cyclodextrins or carbohydrates. The present invention also relates to the use of such compositions in the binding and removal of mycotoxins from foodstuff. The invention also includes compositions that show a broad affinity for mycotoxins.

Claims (11)

1. A method of extracting one or more mycotoxins from a foodstuff, comprising: contacting said foodstuff with a fully aqueous composition comprising 8 g/L of sodium chloride (NaCl), 13.8 g/L of disodium phosphate (Na 2 HPO 4 ), 0.51 g/L of sodium dihydrogen phosphate (NaH 2 PO 4 ), and 30 g/L of a hydroxypropyl-beta-cyclodextrin.

2. The method according to claim 1 , wherein the foodstuff is a grain.

3. The method according to claim 2 , wherein the grain is selected from the group consisting of barley, corn, fonio, kamut, millet, oats, popcorn, rice, rye, sorghum, spelt, teff, triticale, wheat, dry distiller grain, and corn gluten meal.

4. The method according to claim 3 , wherein the grain is selected from the group consisting of corn, barley, wheat, and rice.

5. The method according to claim 1 , wherein the one of more mycotoxins is selected from the group consisting of fumonisin, aflatoxin, zearalenone, ochratoxin, deoxynivalenol, and T2 toxin.

6. The method according to claim 1 , wherein the method comprises the steps of:

a) contacting the foodstuff matrix with the composition;

b) optionally, removing the composition from the foodstuff; and

c) contacting a lateral flow detection apparatus comprising a test strip and mycotoxin detector with the composition from step b.

7. The method according to claim 1 , wherein two or more mycotoxins are extracted from the foodstuff.

8. The method according to claim 7 , wherein the two or more mycotoxins are simultaneously extracted from the foodstuff.

Assignments (2)
SECURITY INTEREST Recorded Sep 2, 2022
From: NEOGEN CORPORATION; NEOGEN FOOD SAFETY US HOLDCO CORPORATION
To: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
Reel/Frame 061372/0264 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 13, 2020
From: SARVER, RONALD W., JR.; BEAUBIEN, RONALD D., JR.; VISWAPRAKASH, NANDURI
To: NEOGEN CORPORATION
Reel/Frame 051807/0672 →
Continuity (4)
Division 15639287 · Jun 30, 2017
Continuation 15171244 · Jun 2, 2016
Continuation PCTUS2014060018 · Oct 10, 2014
Related Publication 20200191786A1 · Jun 18, 2020