IP Library › Patent Application 16785268
Patent Application
App. No. 16/785,268

INJECTABLE PREPARATION

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Quick Facts
Patent No.
US None
App. No.
16/785,268
Abstract

An object of the present invention is to provide a storage-stable injectable preparation comprising a composition comprising a poorly soluble drug as an active ingredient and a dispersion medium. Another object of the present invention is to provide a compact, lightweight prefilled syringe by filling a syringe with the injectable preparation. The present invention provides an injectable preparation comprising a composition comprising a poorly soluble drug, a dispersion medium, and a specific suspending agent, the composition having a viscosity of 40 pascal-seconds or more in at least one point in the shear rate range of 0.01 to 0.02 s −1 and having a viscosity of 0.2 pascal-seconds or less in at least one point in the shear rate range of 900 to 1,000 s −1 , as measured.

Claims (4)

1 . An injectable preparation comprising a composition comprising a poorly soluble drug, a dispersion medium, and a suspending agent, the suspending agent being at least one member selected from the group consisting of (i) and (ii):

(i) polyvinylpyrrolidone, and

(ii) polyethylene glycol and carboxymethyl cellulose or a salt thereof,

the composition having a viscosity of 40 Pa·s or more in at least one point in the shear rate range of 0.01 to 0.02 s −1 and having a viscosity of 0.2 Pa·s or less in at least one point in the shear rate range of 900 to 1,000 s −1 , as measured by a rheometer.