IP Library Granted Patent US 12,044,678
Granted Patent B2
US 12,044,678 · App. 16/791,116 · Granted Jul 23, 2024

Portable device for detection of harmful substances

Inventors: Scott Sundvor (San Francisco, CA); John Paul Walton (San Francisco, CA); Jonathan William Kiel (San Francisco, CA); Jeffrey Mekler (San Francisco, MA); Shireen Taleghani (San Francisco, CA); Jacob Mooney (San Francisco, CA)
Assignee: Nima Acquisition, LLC
G01N33/521G01N33/02G01N33/5308G01N2001/2866
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Quick Facts
Patent No.
US 12,044,678
App. No.
16/791,116
Granted
Jul 23, 2024
Kind
B2
Abstract

A self-contained apparatus and methods for detecting the presence of any specified substance in any medium. A sample of the medium is placed in a capsule, along with a solvent and a sensor configured to test for a target analyte. The solvent comes into contact with the medium in the capsule, and the capsule is agitated to create a dispersion in the solvent of a portion of any target analyte present in the medium. A release mechanism configured to cause conduction of the dispersion to the sensor, so that the sensor produces an indication of presence of the target analyte if the target analyte is present in the medium. The apparatus uses a disposable capsule where the medium in question is placed and the disposable capsule is placed inside a reader and analyzed for presence of the harmful substance.

Claims (47)

1. A capsule for use in a self-contained portable analysis device, the capsule comprising:

an enclosed volume for retaining a solvent and a medium sample;

a cap adapted to permit introduction of the medium sample into the enclosed volume by a user;

a sensor holder for retaining a sensor and adapted for bringing the sensor in contact with contents that include at least a portion of the medium sample mixed with the solvent in the enclosed volume;

a female coupling at an end of the capsule;

wherein the capsule is configured to be received within the self-contained portable analysis device;

wherein a male coupling port of the self-contained portable analysis device is configured to be received within the female coupling of the capsule; and

wherein when the capsule is positioned within the self-contained portable analysis device and the male coupling port of the self-contained portable analysis device is positioned within the female coupling of the capsule a motor of the self-contained portable analysis device is configured to transmit torque to the capsule to rotate the capsule.

2. The capsule in accordance with claim 1 , further comprising a valve positioned between the enclosed volume and the sensor, the valve being adapted to be opened to allow the contents to move into contact the sensor; and

wherein the valve is actuated by a mechanical device including a spring;

wherein the valve is configured to break a seal to allow the contents to contact the sensor.

3. The capsule in accordance with claim 1 , further comprising a filter disposed between the enclosed volume and the sensor.

4. The capsule in accordance with claim 1 , further comprising the sensor that is a test strip that is configured to test for a target analyte that is a food allergen.

5. The capsule in accordance with claim 1 , wherein a motor of the self-contained portable analysis device is configured to be magnetically coupled to the capsule.

6. The capsule in accordance with claim 1 , wherein the capsule comprises a grinder configured to process the medium sample within the capsule; and

wherein a motor of the self-contained portable analysis device is configured to rotate the capsule.

7. The capsule in accordance with claim 1 , wherein the capsule is configured to be axially aligned with the self-contained portable analysis device.

8. The capsule in accordance with claim 1 , wherein the capsule includes a valve adapted to be opened to allow the contents to move out of the enclosed volume and then to contact the sensor; and

wherein the self-contained portable analysis device is configured to open the valve.

9. The capsule in accordance with claim 1 , wherein the sensor includes a test strip that is configured to produce an indication of a presence of a target analyte, based on the target analyte being present in the medium sample.

10. The capsule in accordance with claim 1 , wherein the medium sample is a food substrate.

11. The capsule in accordance with claim 1 , wherein the capsule is configured to be agitated to mix the medium sample and the solvent together in the enclosed volume.

12. The capsule in accordance with claim 11 , wherein the capsule is configured to be agitated by force applied from the user.

13. The capsule in accordance with claim 1 , wherein the cap includes a holder configured to be coupled to a utensil.

14. The capsule in accordance with claim 13 , wherein the utensil is a spoon.

15. The capsule in accordance with claim 1 , further comprising a housing that defines the enclosed volume; and

wherein the cap is removably coupled to the housing.

16. A capsule comprising:

a capsule housing defining an enclosed volume for retaining a solvent and a medium sample;

a cap adapted to permit introduction of the medium sample into the enclosed volume by a user;

a sensor including a test strip that is configured to test for a target analyte that is a food allergen;

a sensor holder that is configured to retain the sensor and adapted for bringing the sensor in contact with contents that include at least a portion of the medium sample mixed with the solvent in the enclosed volume;

a valve configured to open to allow the contents to leave the enclosed volume and then to contact the sensor;

wherein the capsule is configured to be received within a self-contained portable analysis device; and

wherein a motor of the self-contained portable analysis device is configured to be magnetically coupled to the capsule.

17. The capsule of claim 16 , wherein the enclosed volume is isolated from the ambient environment.

18. A capsule comprising:

a capsule housing defining an enclosed volume for retaining a solvent and a medium sample;

a cap adapted to permit introduction of the medium sample into the enclosed volume by a user;

a sensor including a test strip that is configured to test for a target analyte that is a food allergen;

a sensor holder that is configured to retain the sensor and adapted for bringing the sensor in contact with contents that include at least a portion of the medium sample mixed with the solvent in the enclosed volume;

a valve configured to open to allow the contents to leave the enclosed volume and then to contact the sensor;

a female coupling at an end of the capsule;

wherein the capsule is configured to be received within a self-contained portable analysis device;

wherein a male coupling port of the self-contained portable analysis device is configured to be received within the female coupling of the capsule; and

wherein when the capsule is positioned within the self-contained portable analysis device and the male coupling port of the self-contained portable analysis device is positioned within the female coupling of the capsule a motor of the self-contained portable analysis device is configured to transmit torque to the capsule to rotate the capsule.

19. The capsule of claim 16 , wherein the valve is configured to break a seal to allow the contents to contact the sensor.

Assignments (15)
PATENT SECURITY AGREEMENT Recorded Jun 20, 2025
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 071672/0100 →
PARTIAL TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS, RECORDED ON OCTOBER 21, 2021, AT REEL/FRAME 058040/0001 Recorded Jun 20, 2025
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: MEDLINE INDUSTRIES, LP (F/K/A MEDLINE INDUSTRIES, INC.); NIMA PARTNERS, INC. (AS SUCCESSOR-IN-INTEREST TO NIMA ACQUISITION, LLC)
Reel/Frame 071672/0198 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS, RECORDED ON APRIL 1, 2022, AT REEL/FRAME 059476/0640 Recorded Jun 20, 2025
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: NIMA PARTNERS, INC. (AS SUCCESSOR-IN-INTEREST TO NIMA ACQUISITION, LLC)
Reel/Frame 071672/0221 →
PARTIAL TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jun 20, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: MEDLINE INDUSTRIES, LP (F/K/A MEDLINE INDUSTRIES, INC.); NIMA PARTNERS, INC. (AS SUCCESSOR-IN-INTEREST TO NIMA ACQUISITION, LLC)
Reel/Frame 071675/0957 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS (REEL/FRAME 060382/0577) Recorded Jun 20, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: NIMA PARTNERS, INC. (AS SUCCESSOR-IN-INTEREST TO NIMA ACQUISITION, LLC)
Reel/Frame 071676/0468 →
PARTIAL TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS (REEL/FRAME 057927/0091) Recorded Jun 20, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: MEDLINE INDUSTRIES, LP (F/K/A MEDLINE INDUSTRIES, INC.); NIMA PARTNERS, INC. (AS SUCCESSOR-IN-INTEREST TO NIMA ACQUISITION, LLC)
Reel/Frame 071676/0571 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 6, 2025
From: NIMA ACQUISITION, LLC
To: NIMA PARTNERS, INC.
Reel/Frame 070142/0009 →
PATENT SECURITY AGREEMENT Recorded May 17, 2022
From: NIMA ACQUISITION, LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 060382/0577 →
SECURITY INTEREST Recorded Apr 1, 2022
From: NIMA ACQUISITION, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 059476/0640 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: BANK OF AMERICA, N.A.
Reel/Frame 058040/0001 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 057927/0091 →
CHANGE OF NAME Recorded Oct 14, 2021
From: MEDLINE INDUSTRIES, INC.
To: MEDLINE INDUSTRIES, LP
Reel/Frame 057807/0297 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 12, 2020
From: NIMA LABS, INC.
To: NIMA ACQUISITION, LLC
Reel/Frame 054030/0036 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2020
From: SUNDVOR, SCOTT; WALTON, JOHN; KIEL, JONATHAN WILLIAM; MEKLER, JEFFREY; TALEGHANI, SHIREEN; MOONEY, JACOB
To: 6SENSORLABS, INC.
Reel/Frame 052291/0552 →
CHANGE OF NAME Recorded Mar 5, 2020
From: 6SENSORLABS, INC.
To: NIMA LABS, INC.
Reel/Frame 052114/0223 →
Continuity (6)
Division 15910692 · Mar 2, 2018
Continuation 14227543 · Mar 27, 2014
Division 14227543 · Mar 27, 2014
Provisional Application 61874590 · Sep 6, 2013
Provisional Application 61806425 · Mar 29, 2013
Related Publication 20200200738A1 · Jun 25, 2020