Pain management using cryogenic remodeling
Embodiments include methods and systems for treating back pain associated with a nerve. A needle of a cryogenic system may be inserted beneath a skin surface. The needle may include an electrically conducting structure at least partially surrounded by an electrical insulator for conducting electrical energy. The needle may include an outer lumen and an inner lumen extending distally within the outer lumen, the inner lumen include a distal opening open to the outer lumen. The needle may be positioned at a desired location in proximity to the nerve, and a cooling therapy including cooling cycles and thawing periods may be performed to cool tissue at the desired location. The cooling therapy may sufficiently reduce the back pain.
1. A method for treating a back pain associated with a target nerve of a patient, the method comprising:
inserting a distal end of a needle of a cryogenic system into a tissue beneath a skin surface of the patient, wherein the needle comprises an electrically conducting structure at least partially surrounded by an electrical insulator, and wherein the distal end of the needle comprises an electrically conductive surface configured to be able to conduct electrical energy from an electrical source, wherein the needle comprises:
an outer lumen extending distally toward the distal end of the needle, and
an inner lumen extending distally within the outer lumen, the inner lumen comprising a distal opening that is open to the outer lumen;
positioning a distal portion of the needle at a desired location in proximity to the target nerve associated with the back pain; and
performing a first cooling cycle via the distal portion of the needle at the desired location in proximity to the target nerve associated with the back pain so that the needle cools tissue at the desired location;
causing at least a portion of the tissue at the desired location to be thawed over a thawing period; and
performing a second cooling cycle via the distal portion of the needle;
wherein the cooling cycles are configured to reach temperatures less than −19 degrees Celsius, and wherein the cooling cycles sufficiently reduce back pain.
2. The method of claim 1 , wherein the back pain comprises a lower back pain.
3. The method of claim 1 , further comprising:
stimulating the target nerve via the electrically conductive surface to locate the target nerve.
4. The method of claim 1 , wherein performing the first cooling cycle via the distal portion of the needle comprises:
directing a cooling fluid from a cooling fluid source to the distal portion of the needle via a fluidic pathway, the fluidic pathway comprising the cooling fluid source, the inner lumen, and the outer lumen;
wherein a flow of the cooling fluid cools the needle so that the needle cools the tissue at the desired location.
5. The method of claim 4 , wherein the cooling fluid flows from the cooling fluid source to the outer lumen via the inner lumen.
6. The method of claim 4 , further comprising venting the cooling fluid proximally from the distal end of the needle.
7. The method of claim 4 , wherein the cooling fluid is in a liquid state when in the cooling fluid source.
8. The method of claim 4 , wherein the cooling fluid comprises nitrous oxide or carbon dioxide.
9. The method of claim 4 , wherein at least some of the cooling fluid is caused to vaporize into a gaseous state within the needle.
10. The method of claim 4 , further comprising venting the cooling fluid proximally as a gas from the distal end of the needle via the fluidic pathway.
11. The method of claim 1 , wherein the inner lumen comprises a cooling fluid supply tube configured to extend distally of the skin surface when the distal portion of the needle is positioned at the desired location.
12. The method of claim 1 , wherein the second cooling cycle is performed at the desired location in proximity to the target nerve associated with the back pain.
13. The method of claim 1 , wherein causing at least a portion of the tissue at the desired location to be thawed comprises applying a warming energy or injecting a warming fluid to speed thawing of the tissue at the desired location.
14. The method of claim 1 , wherein the needle comprises a 16 gauge or smaller needle.
15. A method for treating a back pain associated with a target nerve of a patient, the method comprising:
inserting a sharpened distal end of a needle of a cryogenic system into a tissue beneath a skin surface of the patient, wherein the needle comprises a 16 gauge or smaller needle, and wherein the needle includes:
an outer lumen extending distally toward the distal end of the needle, and
an inner lumen extending distally within the outer lumen, the inner lumen comprising a distal opening that is open to the outer lumen;
positioning a distal portion of the needle beneath the skin surface at a desired location in proximity to the target nerve associated with the back pain; and
performing a first cooling cycle via the distal portion of the needle at the desired location in proximity to the target nerve associated with the back pain so that the needle cools tissue at the desired location;
causing at least a portion of the tissue at the desired location to be thawed over a thawing period; and
performing a second cooling cycle via the distal portion of the needle;
wherein the cooling cycles are configured to reach temperatures less than −19 degrees Celsius, and wherein the cooling cycles sufficiently reduce back pain.
16. The method of claim 15 , wherein the back pain comprises a lower back pain.
17. The method of claim 15 , wherein the needle comprises an 18 gauge or smaller needle.
18. The method of claim 15 , wherein performing the first cooling cycle via the distal portion of the needle comprises:
directing a cooling fluid from a cooling fluid source to the distal portion of the needle via a fluidic pathway, the fluidic pathway comprising the cooling fluid source, the inner lumen, and the outer lumen;
wherein a flow of the cooling fluid cools the needle so that the needle cools the tissue at the desired location.
19. The method of claim 18 , further comprising venting the cooling fluid proximally from the distal end of the needle.
20. The method of claim 18 , wherein the cooling fluid flows from the cooling fluid source to the outer lumen via the inner lumen.
21. The method of claim 18 , wherein the cooling fluid comprises nitrous oxide (N2O) or carbon dioxide (CO2).
22. The method of claim 18 , wherein the cooling fluid is in a liquid state when in the cooling fluid source.
23. The method of claim 22 , wherein at least some of the cooling fluid is caused to vaporize into a gaseous state within the needle.
24. The method of claim 18 , further comprising venting the cooling fluid proximally as a gas from the distal end of the needle via the fluidic pathway.
25. The method of claim 15 , wherein causing at least a portion of the tissue at the desired location to be thawed comprises applying a warming energy or injecting a warming fluid to speed thawing of the tissue at the desired location.
26. The method of claim 15 , wherein the inner lumen comprises a cooling fluid supply tube configured to extend distally of the skin surface when the distal portion of the needle is positioned at the desired location.
27. The method of claim 15 , further comprising stimulating the target nerve to locate the target nerve.
28. The method of claim 15 , wherein the second cooling cycle is performed at the desired location in proximity to the target nerve associated with the back pain.