IP Library Granted Patent US 12,106,837
Granted Patent B2
US 12,106,837 · App. 16/802,753 · Granted Oct 1, 2024

Occlusion resolution in medication delivery devices, systems, and methods

Inventors: Bryan Mazlish (Palo Alto, CA); Lane Desborough (Thousand Oaks, CA); Ravi Shankar Rontala Raghunathan (Union City, CA)
Assignee: Insulet Corporation
G16H20/17A61M5/00A61M5/16854A61M5/172A61M5/1723A61M2005/16863A61M2202/07A61M2205/18A61M2205/332A61M2205/3331A61M2205/3334A61M2205/3569A61M2205/3584A61M2205/502A61M2205/581A61M2205/582A61M2205/583A61M2205/587A61M2230/201
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,106,837
App. No.
16/802,753
Granted
Oct 1, 2024
Kind
B2
Abstract

Methods, devices, and systems of delivering infusion fluid (e.g., medication such as insulin) can detect, at multiple times during a dispensation period of time, a pressure level of the infusion fluid in an infusion fluid pathway, either directly or indirectly. Based on the detected pressure levels, one or more actual dispensation times that are after an intended dispensation time can be determined. In some cases, methods, devices, and systems provided herein can use variable occlusion alarm thresholds, which can depend on variables such as an age of an infusion set and/or a current analyte level. In some cases, methods, devices, and systems provided herein can automate medication delivery and use the actual dispensation times in a control algorithm determining medication deliveries.

Claims (24)

1. A method for detecting an occlusion in an automated medication delivery system comprising:

detecting at least one real-time analyte level for a user;

based at least partially on the detected at least one real-time analyte level, determining a variable pressure threshold;

determining a dosage of medication for delivery to the user based on the at least one real-time analyte level, wherein the dosage of medication is determined without user input;

initiating a dispensation of the determined dosage of the medication using a medication delivery device;

measuring a pressure of the medication in an infusion fluid pathway of the medication delivery device; and

initiating an occlusion alarm if the measured pressure exceeds the variable pressure threshold.

2. The method of claim 1 , wherein the variable pressure threshold is further dependent on a timing of one or more recent dispensations, amount of one or more recent dispensations, type of one or more recent dispensations, or a combination thereof.

3. The method of claim 1 , wherein the medication is insulin and the analyte levels are glucose levels.

4. The method of claim 1 , wherein measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device comprises measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device at multiple times during a dispensation period of time, the method further comprising:

comparing each of the pressure measurements detected at the multiple times during the dispensation period to the variable pressure threshold; and

determining, based on one or more of the detected pressure measurements exceeding the variable pressure threshold, that an intended dispensation did not enter the user.

5. The method of claim 1 , wherein measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device comprises measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device at multiple times during a dispensation period of time, the method further comprising:

comparing each of the pressure measurements detected at the multiple times during the dispensation period to the variable pressure threshold; and

indicating via an alert, based on one or more of the detected pressure measurements exceeding the variable pressure threshold, that the dispensation was delayed.

6. A method for detecting an occlusion in an automated medication delivery system comprising:

detecting at least one real-time analyte level for a user;

based at least partially on the detected at least one real-time analyte level, determining a variable pressure threshold;

determining a dosage of medication for delivery to the user based on the at least one real-time analyte level;

initiating a dispensation of the determined dosage of the medication using a medication delivery device;

measuring a pressure of the medication in an infusion fluid pathway of the medication delivery device; and

initiating an occlusion alarm if the measured pressure exceeds the variable pressure threshold.

7. The method of claim 6 , wherein the variable pressure threshold is further dependent on a timing of one or more recent dispensations, amount of one or more recent dispensations, type of one or more recent dispensations, or a combination thereof.

8. The method of claim 6 , wherein the medication is insulin and the analyte is glucose.

Assignments (16)
SECURITY INTEREST Recorded Jan 10, 2025
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069870/0519 →
SECURITY INTEREST Recorded Jan 10, 2025
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069870/0456 →
SECURITY INTEREST Recorded Sep 30, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069073/0912 →
SECURITY INTEREST Recorded Sep 30, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069074/0001 →
SECURITY INTEREST Recorded Sep 24, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069030/0296 →
SECURITY INTEREST Recorded Sep 24, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069030/0104 →
SECURITY INTEREST Recorded Sep 23, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069019/0142 →
SECURITY INTEREST Recorded Sep 23, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069019/0188 →
SECURITY INTEREST Recorded Sep 12, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 068948/0324 →
SECURITY INTEREST Recorded Sep 12, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 068948/0172 →
SECURITY AGREEMENT SUPPLEMENT Recorded Sep 7, 2023
From: INSULET CORPORATION
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 064840/0181 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2023
From: BIGFOOT BIOMEDICAL, INC.
To: INSULET CORPORATION
Reel/Frame 062900/0001 →
RELEASE OF SECURITY INTEREST Recorded Feb 17, 2023
From: MADRYN FUND ADMINISTRATION, LLC
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 062793/0316 →
SECURITY INTEREST Recorded Feb 10, 2023
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 062702/0145 →
SECURITY INTEREST Recorded Mar 12, 2021
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 055583/0044 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2020
From: MAZLISH, BRYAN; DESBOROUGH, LANE; RAGHUNATHAN, RAVI SHANKAR
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 052378/0119 →
Continuity (3)
Division 15404442 · Jan 12, 2017
Provisional Application 62278974 · Jan 14, 2016
Related Publication 20200206421A1 · Jul 2, 2020