IP Library Granted Patent US 11,058,698
Granted Patent B2
US 11,058,698 · App. 16/803,284 · Granted Jul 13, 2021

Acylated active agents and methods of their use for the treatment of autoimmune disorders

Inventors: Steven John Taylor (Winchester, MA); Mi-Jeong Kim (Boston, MA); Kathleen Nudel (Jamaica Plain, MA); Timothy F. Briggs (Waltham, MA); Koji Yasuda (Boston, MA); Leonard Buckbinder (East Greenwich, RI); Bernard Lanter (Somerville, MA); Spencer Cory Peck (Watertown, MA); Cheri Snedeker (Boston, MA); Angela She (Cambridge, MA); Jessica Alexander (Waltham, MA); Anna Liang (Everett, MA); Jenny Liu (Cambridge, MA); Dinara Gunasekera (Cambridge, MA); David Arthur Berry (Waban, MA); John Patrick Casey, Jr. (Boston, MA); Amir H. Moarefi (Encino, CA)
Assignee: Flagship Pioneering Innovations V, Inc.
A61K31/7036A61K9/0053A61K31/191A61K31/196A61K31/353A61K31/519A61P37/06
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Quick Facts
Patent No.
US 11,058,698
App. No.
16/803,284
Granted
Jul 13, 2021
Kind
B2
Abstract

Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.

Claims (3)

1. A compound of the following structure:

or a pharmaceutically acceptable salt thereof.

2. A composition comprising an excipient and the compound of claim 1 or a pharmaceutically acceptable salt thereof.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2021
From: SENDA BIOSCIENCES, INC.
To: FLAGHIP PIONEERING, INC.
Reel/Frame 056198/0528 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2021
From: FLAGSHIP PIONEERING, INC.
To: FLAGSHIP PIONEERING INNOVATIONS V, INC.
Reel/Frame 056198/0536 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2021
From: MOAREFI, AMIR
To: SENDA BIOSCIENCES, INC.
Reel/Frame 056200/0239 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2020
From: CASEY, JOHN PATRICK, JR.; BERRY, DAVID ARTHUR
To: FLAGSHIP PIONEERING, INC.
Reel/Frame 053165/0031 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2020
From: TAYLOR, STEVEN JOHN; KIM, MI-JEONG; NUDEL, KATHLEEN; BRIGGS, TIMOTHY F.; YASUDA, KOJI; BUCKBINDER, LEONARD; LANTER, BERNARD; PECK, SPENCER CORY; SNEDEKER, CHERI; LIU, JENNY; SHE, ANGELA; ALEXANDER, JESSICA; LIANG, ANNA; GUNASEKERA, DINARA
To: KINTAI THERAPEUTICS, INC.
Reel/Frame 053165/0591 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2020
From: KINTAI THERAPEUTICS, INC.
To: FLAGSHIP PIONEERING, INC.
Reel/Frame 053165/0656 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2020
From: FLAGSHIP PIONEERING, INC.
To: FLAGSHIP PIONEERING INNOVATIONS V, INC.
Reel/Frame 053165/0704 →
Continuity (4)
Continuation PCTUS2019035677 · Jun 5, 2019
Provisional Application 62776377 · Dec 6, 2018
Provisional Application 62680965 · Jun 5, 2018
Related Publication 20200188418A1 · Jun 18, 2020