IP Library Granted Patent US 11,224,363
Granted Patent B2
US 11,224,363 · App. 16/804,507 · Granted Jan 18, 2022

Active-pulse blood analysis system

Inventors: Massi Joe E. Kiani (Laguna Niguel, CA); Mathew Paul (Irvine, CA); Jesse Chen (Foothill Ranch, CA); Marcelo M. Lamego (Cupertino, CA)
Assignee: MASIMO CORPORATION
A61B5/14552A61B5/6826A61B5/721A61B5/7207
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Quick Facts
Patent No.
US 11,224,363
App. No.
16/804,507
Granted
Jan 18, 2022
Kind
B2
Abstract

An active-pulse blood analysis system has an optical sensor that illuminates a tissue site with multiple wavelengths of optical radiation and outputs sensor signals responsive to the optical radiation after attenuation by pulsatile blood flow within the tissue site. A monitor communicates with the sensor signals and is responsive to arterial pulses within a first bandwidth and active pulses within a second bandwidth so as to generate arterial pulse ratios and active pulse ratios according to the wavelengths. An arterial calibration curve relates the arterial pulse ratios to a first arterial oxygen saturation value and an active pulse calibration curve relates the active pulse ratios to a second arterial oxygen saturation value. Decision logic outputs one of the first and second arterial oxygen saturation values based upon perfusion and signal quality.

Claims (32)

1. A blood analysis method comprising:

inputting optical sensor data;

determining arterial pulse data from the optical sensor data;

calculating arterial pulse ratios from the arterial pulse data;

determining active pulse data from the optical sensor data;

calculating active pulse ratios from the active pulse data;

applying an arterial calibration curve stored in one or more memory devices to the arterial pulse ratios so as to generate an SpO 2 parameter indicative of arterial oxygen saturation determined from an arterial pulse;

applying an active pulse calibration curve stored in the one or more memory devices to the active pulse ratios so as to generate an SpO 2 AP parameter indicative of arterial oxygen saturation determined from an active pulse; and

choosing between the SpO 2 parameter and the SpO 2 AP parameter so as to generate an SpO 2 M output parameter, the SpO 2 M output parameter comprising either the SpO 2 parameter or the SpO 2 AP parameter based on signal conditions of the optical sensor data a Boolean signal quality (BSQ) and a Boolean perfusion index (BPI).

2. The blood analysis method of claim 1 , wherein the SpO 2 M output parameter is indicative of an arterial oxygen saturation measurement tolerant to at least one of motion, low perfusion, and low signal quality.

3. The blood analysis method of claim 1 , further comprising measuring a perfusion index (PI), and wherein the Boolean perfusion input (BPI) is zero when the perfusion index (PI) is below a first threshold boundary.

4. The blood analysis method of claim 3 , further comprising measuring an acceleration of an optical sensor, and wherein the Boolean signal quality (BSQ) is zero when the measured acceleration is above a second threshold boundary.

5. The blood analysis method of claim 4 , wherein the first threshold boundary is a perfusion index (PI) of 1%.

6. The blood analysis method of claim 5 , wherein the second threshold boundary is an acceleration of 0.3 g.

7. The blood analysis method of claim 1 , wherein the arterial calibration curve relates arterial pulse ratios to oxygen saturation values.

8. The blood analysis method of claim 7 , wherein the active pulse calibration curve relates active pulse ratios to oxygen saturation values.

9. A blood analysis system comprising:

an optical sensor configured to transmit multiple wavelengths of light into a tissue site and to detect the transmitted light after attenuation by arterial blood flow and active pulsed blood flow within the tissue site so as to generate optical sensor data;

one or more memory devices storing an arterial calibration curve and an active pulse calibration curve; and

a processor configured to:

determine arterial pulse data from the optical sensor data and determine arterial pulse ratios from the arterial pulse data;

determine active pulse data from the optical sensor data and determine active pulse ratios from the active pulse data;

apply the arterial calibration curve to the arterial pulse ratios so as to generate an SpO 2 parameter indicative of arterial oxygen saturation determined from an arterial pulse;

apply the active pulse calibration curve to the active pulse ratios so as to generate an SpO 2 AP parameter indicative of arterial oxygen saturation determined from an active pulse; and

select between the SpO 2 parameter and the SpO 2 AP parameter so as to generate an SpO 2 M output parameter, the SpO 2 M output parameter comprising either the SpO 2 parameter or the SpO 2 AP parameter based on a Boolean signal quality (BSQ) and a Boolean perfusion index (BPI) of the optical sensor data.

10. The blood analysis system of claim 9 , wherein the SpO 2 M output parameter is indicative of an arterial oxygen saturation measurement tolerant to at least one of motion, low perfusion, and low signal quality.

11. The blood analysis system of claim 9 , wherein the processor is further configure to determine a perfusion index (PI), and wherein the Boolean perfusion input (BPI) is zero when the perfusion index (PI) is below a first threshold boundary.

12. The blood analysis system of claim 11 , further comprising an accelerometer associated with the optical sensor, and wherein the Boolean signal quality (BSQ) is zero when a measured acceleration is above a second threshold boundary.

13. The blood analysis system of claim 12 , wherein the first threshold boundary is a perfusion index (PI) of 1%.

14. The blood analysis system of claim 13 , wherein the second threshold boundary is an acceleration of 0.3 g.

15. The blood analysis system of claim 9 , wherein the arterial calibration curve relates arterial pulse ratios to oxygen saturation values.

16. The blood analysis system of claim 9 , wherein the active pulse calibration curve relates active pulse ratios to oxygen saturation values.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2020
From: KIANI, MASSI JOE E.; PAUL, MATHEW; CHEN, JESSE; LAMEGO, MARCELO M.
To: MASIMO CORPORATION
Reel/Frame 053263/0589 →
Continuity (6)
Continuation 15670405 · Aug 7, 2017
Continuation 14328694 · Jul 10, 2014
Continuation In Part 14153393 · Jan 13, 2014
Provisional Application 61752976 · Jan 16, 2013
Provisional Application 61844699 · Jul 10, 2013
Related Publication 20200305777A1 · Oct 1, 2020
Cited By (2)
US 12,193,813 US 12,329,548