IP Library Granted Patent US 11,324,418
Granted Patent B2
US 11,324,418 · App. 16/817,402 · Granted May 10, 2022

Multi-coil magnetic resonance imaging using deep learning

Inventors: Jo Schlemper (Long Island City, NY); Seyed Sadegh Moshen Salehi (Bloomfield, NJ); Michal Sofka (Princeton, NJ)
Assignee: Hyperfine Operations, Inc.
A61B5/055G01R33/36G01R33/383G01R33/445G01R33/5608G01R33/5611G06K9/6203G06K9/6245G06K9/741G06K9/748G06N3/0454G06N3/08G06N3/082G06T3/60G06T7/0012G06T7/262G06T7/38G06T11/006G06T11/008G16H30/40G06T2207/10088G06T2207/20056G06T2207/20081G06T2207/20084G06T2207/20182G06T2207/20216G06T2207/20224G06T2207/30016G06T2210/41
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Quick Facts
Patent No.
US 11,324,418
App. No.
16/817,402
Granted
May 10, 2022
Kind
B2
Abstract

Techniques for generating magnetic resonance (MR) images from MR data obtained by a magnetic resonance imaging (MRI) system comprising a plurality of RF coils configured to detect RF signals. The techniques include: obtaining a plurality of input MR datasets obtained by the MRI system to image a subject, each of the plurality of input MR datasets comprising spatial frequency data and obtained using a respective RF coil in the plurality of RF coils; generating a respective plurality of MR images from the plurality of input MR datasets by using an MR image reconstruction technique; estimating, using a neural network model, a plurality of RF coil profiles corresponding to the plurality of RF coils; generating an MR image of the subject using the plurality of MR images and the plurality of RF coil profiles; and outputting the generated MR image.

Claims (42)

1. A method for generating magnetic resonance (MR) images from MR data obtained by a magnetic resonance imaging (MRI) system comprising a plurality of RF coils configured to detect RF signals, the method comprising:

obtaining a plurality of input MR datasets obtained by the MRI system to image a subject, each of the plurality of input MR datasets comprising spatial frequency data and obtained using a respective RF coil in the plurality of RF coils, wherein the MRI system comprises at least 8 RF coils and the plurality of input MR datasets comprises at least 8 input MR datasets;

generating a respective plurality of MR images from the plurality of input MR datasets by using an MR image reconstruction technique;

estimating, using a neural network model, a plurality of RF coil profiles corresponding to the plurality of RF coils;

generating an MR image of the subject using the plurality of MR images and the plurality of RF coil profiles; and

outputting the generated MR image.

2. The method of claim 1 , further comprising using the MRI system to image the subject to obtain the plurality of input MR datasets.

3. The method of claim 1 , wherein generating the respective plurality of MR images from the plurality of input MR datasets is performed using a neural network MR image reconstruction technique.

4. The method of claim 1 , wherein generating the respective plurality of MR images from the plurality of input MR datasets is performed using a compressed sensing MR image reconstruction technique.

5. The method of claim 1 , wherein the neural network model comprises one or more convolutional layers.

6. The method of claim 1 , wherein generating the MR image of the subject using the plurality of MR images and the plurality of RF coil profiles comprises:

generating the MR image of the subject as a weighted combination of the plurality of MR images, each of the plurality of MR images being weighted by a respective RF coil profile in the plurality of RF coil profiles.

7. The method of claim 1 ,

wherein the plurality of MR images comprises a first MR image generated from a first input MR dataset obtained using a first RF coil of the plurality of RF coils, and

wherein generating the MR image of the subject comprises weighting different pixels of the first MR image using different values of a first RF coil profile among the plurality of RF coil profiles, the first RF coil profile being associated with the first RF coil.

8. A magnetic resonance imaging (MRI) system, comprising:

a magnetics system having a plurality of magnetics components to produce magnetic fields for performing MRI, the magnetics system comprising:

a plurality of RF coils configured to detect MR signals; and

at least one permanent B 0 magnet configured to produce a B 0 field for an imaging region of the MRI system, the B 0 field having a strength between 50 milliTesla and 100 milliTesla; and

at least one processor configured to perform:

obtaining a plurality of input MR datasets obtained by the MRI system to image a subject, each of the plurality of input MR datasets comprising spatial frequency data and obtained using a respective RF coil in the plurality of RF coils;

generating a respective plurality of MR images from the plurality of input MR datasets by using an MR image reconstruction technique;

estimating, using a neural network model, a plurality of RF coil profiles corresponding to the plurality of RF coils;

generating an MR image of the subject using the plurality of MR images and the plurality of RF coil profiles; and

outputting the generated MR image.

9. The MRI system of claim 8 , wherein the at least one permanent B 0 magnet comprises a plurality of concentric permanent magnet rings.

10. The MRI system of claim 8 , wherein the plurality of magnetics components include at least one gradient coil.

11. At least one non-transitory computer readable storage medium storing processor-executable instructions that, when executed by at least one processor, cause the at least one processor to perform a method for generating magnetic resonance (MR) images of a subject from MR data obtained by a magnetic resonance imaging (MRI) system having a plurality of RF coils configured to detect MR signals, the method comprising:

obtaining a plurality of input MR datasets obtained by the MRI system to image a subject, each of the plurality of input MR datasets comprising spatial frequency data and obtained using a respective RF coil in the plurality of RF coils, wherein the MRI system comprises at least 8 RF coils and the plurality of input MR datasets comprises at least 8 input MR datasets;

generating a respective plurality of MR images from the plurality of input MR datasets by using an MR image reconstruction technique;

estimating, using a neural network model, a plurality of RF coil profiles corresponding to the plurality of RF coils;

generating an MR image of the subject using the plurality of MR images and the plurality of RF coil profiles; and

outputting the generated MR image.

12. The at least one non-transitory computer readable storage medium of claim 11 , further comprising using the MRI system to image the subject to obtain the plurality of input MR datasets.

13. The at least one non-transitory computer readable storage medium of claim 11 , wherein generating the respective plurality of MR images from the plurality of input MR datasets is performed using a neural network MR image reconstruction technique.

14. The at least one non-transitory computer readable storage medium of claim 11 , wherein generating the respective plurality of MR images from the plurality of input MR datasets is performed using a compressed sensing MR image reconstruction technique.

15. The at least one non-transitory computer readable storage medium of claim 11 , wherein the neural network model comprises one or more convolutional layers.

16. The at least one non-transitory computer readable storage medium of claim 11 , wherein generating the MR image of the subject using the plurality of MR images and the plurality of RF coil profiles comprises:

generating the MR image of the subject as a weighted combination of the plurality of MR images, each of the plurality of MR images being weighted by a respective RF coil profile in the plurality of RF coil profiles.

17. The at least one non-transitory computer readable storage medium of claim 11 ,

wherein the plurality of MR images comprises a first MR image generated from a first input MR dataset obtained using a first RF coil of the plurality of RF coils, and

wherein generating the MR image of the subject comprises weighting different pixels of the first MR image using different values of a first RF coil profile among the plurality of RF coil profiles, the first RF coil profile being associated with the first RF coil.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE THIRD INVENTOR NAME SHOULD BE CORRECTED TO READ SEYED SADEGH MONSENI SALEHI PREVIOUSLY RECORDED AT REEL: 056675 FRAME: 0040. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 19, 2022
From: SCHLEMPER, JO; SOFKA, MICHAL; SALEHI, SEYED SADEGH MOHSENI
To: HYPERFINE RESEARCH, INC.
Reel/Frame 060728/0796 →
CHANGE OF NAME Recorded Mar 7, 2022
From: HYPERFINE, INC.
To: HYPERFINE OPERATIONS, INC.
Reel/Frame 059332/0615 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 24, 2021
From: SCHLEMPER, JO; SOFKA, MICHAL; MOSHEN SALEHI, SEYED SADEGH
To: HYPERFINE RESEARCH, INC.
Reel/Frame 056675/0040 →
CHANGE OF NAME Recorded Jun 24, 2021
From: HYPERFINE RESEARCH, INC.
To: HYPERFINE, INC.
Reel/Frame 056675/0186 →
Continuity (4)
Provisional Application 62926890 · Oct 28, 2019
Provisional Application 62820119 · Mar 18, 2019
Provisional Application 62818148 · Mar 14, 2019
Related Publication 20200294287A1 · Sep 17, 2020