IP Library Granted Patent US 12,114,840
Granted Patent B2
US 12,114,840 · App. 16/820,451 · Granted Oct 15, 2024

DNA collection device

Inventors: Robin Y. Smith (Boston, MA); Mike Robbat (Boston, MA)
Assignee: SAPPHIROS LABORATORIES LLC
A61B10/02C12N15/1003A61B2010/0216
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Quick Facts
Patent No.
US 12,114,840
App. No.
16/820,451
Granted
Oct 15, 2024
Kind
B2
Abstract

The disclosed technology relates generally to devices, kits, and related methods for collecting biological samples for genetic testing. In various embodiments, a DNA collection device for collecting cells from an orifice of a human subject includes an elongate arm. The DNA collection device further includes a swab head disposed at a distal end of the elongate arm, wherein the swab head is sized to at least partially enter the orifice, and wherein the swab head comprises a plurality of bristles disposed on a surface of the swab head.

Claims (13)

1. A DNA collection device for collecting cells from an orifice of a human subject, the device comprising:

an elongate arm;

a well plate having a plurality of wells with a first spacing between each well; and

a swab head disposed at a distal end of the elongate arm, wherein the swab head is sized to at least partially enter the orifice, and wherein the swab head comprises a plurality of bristle sets disposed on a surface of the swab head, each bristle set within the plurality of bristle sets comprising one or more bristles bundled together, the bristles within each bristle set separated by no more than a bristle diameter, and wherein the bristle sets have the same first spacing as the well plate.

2. The device of claim 1 , wherein the orifice is a mouth and the swab head is configured to collect buccal cells.

3. The device of claim 1 , wherein the bristles of the bristle sets are of a same length, and extend outwards in a same direction from the surface of the swab head.

4. The device of claim 1 , wherein the bristle set has a length corresponding to a depth of the wells in the well plate.

5. A DNA collection kit comprising: the DNA collection device of claim 4 ; and a containment device comprising a housing for the collection device.

6. The device of claim 1 , wherein at least a portion of the bristle sets are evenly spaced on a surface of the swab head.

7. The device of claim 1 , wherein the swab head has a cylindrical shape and at least a portion of the plurality of bristle sets are disposed on a circumferential surface thereof.

8. The device of claim 1 , further comprising a protective sleeve removably disposed about at least the swab head.

9. The device of claim 8 , wherein the protective sleeve comprises: a removable hood; and

a base disposed about and secured to at least a portion of the elongate arm, wherein the base is operable to sealingly engage with the hood.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 26, 2022
From: SEAPORT DIAGNOSTICS, INC.
To: SAPPHIROS LABORATORIES LLC
Reel/Frame 060028/0276 →
CHANGE OF NAME Recorded May 26, 2022
From: ORIG3N, INC.
To: SEAPORT DIAGNOSTICS, INC.
Reel/Frame 060389/0510 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2020
From: SMITH, ROBIN Y.; ROBBAT, MICHAEL J.
To: ORIG3N, INC.
Reel/Frame 054168/0607 →
Continuity (2)
Provisional Application 62818941 · Mar 15, 2019
Related Publication 20200289098A1 · Sep 17, 2020