IP Library Granted Patent US 11,596,785
Granted Patent B2
US 11,596,785 · App. 16/833,388 · Granted Mar 7, 2023

Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors

Inventors: Samuel Richard Hamner (San Francisco, CA); Kathryn H. Rosenbluth (San Francisco, CA); Serena HanYing Wong (Palo Alto, CA); Swaril Mathur (Laguna Niguel, CA); Paula Jean Chidester (Menlo Park, CA); Terence D. Sanger (Los Angeles, CA)
Assignee: Cala Health, Inc.
A61N1/0456A61N1/048A61N1/0484A61N1/36003A61N1/36031
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Quick Facts
Patent No.
US 11,596,785
App. No.
16/833,388
Granted
Mar 7, 2023
Kind
B2
Abstract

Systems, devices, and methods for stimulating peripheral nerves in the fingers or hand to treat tremor are described. For example, a wearable ring device for delivering electrical stimulation to sensory nerves in a patient's finger can include an annular ring having a plurality of electrodes and a detachable unit having a power source and a pulse generator.

Claims (33)

1. A wearable ring device for treating hand tremors by electrically stimulating one or more sensory nerves on a finger of a patient's hand, the device comprising:

an annular member defining an aperture that is sized to receive a finger of the patient;

a first electrode, a second electrode, and a third electrode housed on an inside surface of the annular member and configured to be in contact with the patient's skin when worn on the finger; and

a stimulation unit that is configured to connect to the annular member, wherein when the unit is connected to the annular member the unit is in electrical communication to the first electrode, the second electrode, and the third electrode, wherein the unit houses a power source and a pulse generator configured to deliver pulsed electrical stimulation to the one or more sensory nerves in the finger,

wherein when worn the first electrode is configured to be positioned on the dorsal side of the finger, the second electrode is configured to be positioned on the palmar side of the finger, and the third electrode is configured to be positioned between the first and second electrodes.

2. The device of claim 1 , wherein the third electrode is a common ground electrode.

3. The device of claim 1 , wherein the finger is the index finger, middle finger, or the ringer finger.

4. The device of claim 1 , further comprising a fourth electrode housed on the inside surface of the annular member.

5. The device of claim 1 , wherein the power source is a capacitor.

6. The device of claim 1 , wherein the power source is a rechargeable battery.

7. The device of claim 1 , wherein the stimulation unit is detachable.

8. The device of claim 1 , wherein the third electrode is configured to be positioned approximately equidistant between the first and second electrodes when the device is worn.

9. The device of claim 1 , wherein the first, second, and third electrodes comprise a dry conductive polymer or rubber with a textured surface configured to capture moisture from the skin, air, or other external sources.

10. The device of claim 1 , wherein the first, second, and third electrodes comprise a wicking conductive fabric configured to capture moisture from the skin, air, or other external sources.

11. The device of claim 1 , further comprising a wireless transceiver electrically connected to the pulse generator and configured to communicate with at least one external electronic device.

12. The device of claim 1 , wherein the annular member comprises a flexible housing material, and the first, second, and third electrodes are electrically connected with flexible electronic circuitry that is configured to conform to a predetermined range of finger diameters and configured to accommodate variation in finger diameter over time.

13. The device of claim 1 , wherein the annular member comprises one or more motion sensors, and wherein the pulse generator is configured to modulate the pulsed electrical stimulation based on measurements of tremor motion and activity from the one or more motion sensors, wherein the one or more motion sensors are selected from the group consisting of an inertial measurement unit, an accelerometer, a gyroscope, and a magnetometer.

14. The device of claim 1 , wherein the inside surface of the annular member is free from gels and adhesives.

15. The device of claim 1 , further comprising a second annular member defining an aperture that is sized to receive the finger of the patient, wherein the second annular member comprises one or more motion sensors configured to measure motion of the patient's hand.

16. A wearable ring device for treating hand tremors by electrically stimulating one or more sensory nerves on a finger of a patient's hand, the device comprising:

an annular member defining an aperture that is sized to receive a finger of the patient;

a first electrode, a second electrode, and a third electrode housed on an inside surface of the annular member and configured to be in contact with the patient's skin when worn on the finger; and

a stimulation unit that is configured to connect to the annular member, wherein when the unit is connected to the annular member the unit is in electrical communication to the first electrode, the second electrode, and the third electrode, wherein the unit houses a power source and a pulse generator configured to deliver pulsed electrical stimulation to the one or more sensory nerves in the finger,

wherein the annular member comprises one or more motion sensors, and wherein the pulse generator is configured to modulate the pulsed electrical stimulation based on measurements of tremor motion and activity from the one or more motion sensors, wherein the one or more motion sensors are selected from the group consisting of an inertial measurement unit, an accelerometer, a gyroscope, and a magnetometer.

17. The device of claim 16 , wherein the one or more motion sensors in the annular member along with a processor located in the stimulation unit or at least one external device are configured to measure and detect one or more predetermined motions and to modulate the pulsed electrical stimulation based on the measurement and detection of the one or more predetermined motions.

18. The device of claim 17 , wherein one or more predetermined motions is selected from the group consisting of knocking the hand of the patient on an object a predetermined number of times, raising the arm up, waving the hand, opening and closing the hand, tapping the finger on a table a predetermined number of times, snapping the fingers, clapping of hands, and pointing.

19. A wearable ring device for treating hand tremors by electrically stimulating one or more sensory nerves on a finger of a patient's hand, the device comprising:

an annular member defining an aperture that is sized to receive a finger of the patient;

a first electrode, a second electrode, and a third electrode housed on an inside surface of the annular member and configured to be in contact with the patient's skin when worn on the finger;

a stimulation unit that is configured to connect to the annular member, wherein when the unit is connected to the annular member the unit is in electrical communication to the first electrode, the second electrode, and the third electrode, wherein the unit houses a power source and a pulse generator configured to deliver pulsed electrical stimulation to the one or more sensory nerves in the finger; and

a second annular member defining an aperture that is sized to receive the finger of the patient, wherein the second annular member comprises one or more motion sensors configured to measure motion of the patient's hand.

20. The device of claim 19 , wherein the second annular member is configured to communicate with the stimulation unit and/or the at least one external device.

21. The device of claim 19 , wherein the second annular member is configured to detachably connect to the stimulation unit.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Feb 25, 2026
From: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
To: CALA HEALTH, INC.
Reel/Frame 073890/0716 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Feb 24, 2026
From: CALA HEALTH, INC.
To: TRINITY CAPITAL INC.
Reel/Frame 074971/0532 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE CORRESPONDENT NAME PREVIOUSLY RECORDED AT REEL: 006005 FRAME: 0030. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Aug 3, 2022
From: CALA HEALTH, INC.
To: CALA HEALTH, INC.
Reel/Frame 061069/0675 →
CHANGE OF ADDRESS Recorded Apr 12, 2022
From: CALA HEALTH, INC.
To: CALA HEALTH, INC.
Reel/Frame 060005/0030 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2022
From: HAMNER, SAMUEL RICHARD; ROSENBLUTH, KATHRYN H.; WONG, SERENA HANYING; MATHUR, SWARIL; CHIDESTER, PAULA JEAN; SANGER, TERENCE D.
To: CALA HEALTH, INC.
Reel/Frame 059465/0597 →
SECURITY INTEREST Recorded Jul 15, 2021
From: CALA HEALTH, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 056862/0017 →
Cited By (5)
US 12,233,265 US 12,357,824 US 12,420,082 US 12,453,853 US 12,629,522