Multi-stream data collection system for noninvasive measurement of blood constituents
The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
1. A multi-channel physiological parameter measurement device comprising:
one or more light emitters;
a substrate having a surface;
a first plurality of photodiodes arranged on the surface and configured to provide a first detector channel, wherein:
the first plurality of photodiodes comprises at least four photodiodes, and
the photodiodes of the first plurality of photodiodes together provide the first detector channel responsive to light from at least one of the one or more light emitters attenuated by body tissue;
a second plurality of photodiodes arranged on the surface and configured to provide a second detector channel, wherein:
the second plurality of photodiodes comprises at least four photodiodes,
the photodiodes of the second plurality of photodiodes together provide the second detector channel responsive to light from at least one of the one or more light emitters attenuated by body tissue,
at least one of the first detector channel or the second detector channel includes information usable to determine a physiological parameter of a wearer of the multi-channel physiological parameter measurement device, and
the physiological parameter comprises at least one of: pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide;
first preprocessing electronics configured to preprocess the first detector channel, the first preprocessing electronics comprising at least a first amplifier configured to receive the first detector channel and at least amplify the first detector channel;
second preprocessing electronics configured to preprocess the second detector channel, the second preprocessing electronics comprising at least a second amplifier configured to receive the second detector channel and at least amplify the second detector channel;
a wall extending from the surface and configured to surround at least the first and second pluralities of photodiodes;
a cover arranged to cover at least a portion of the surface of the substrate, wherein:
the cover comprises a protrusion that extends over all of the photodiodes of the first and second pluralities of photodiodes arranged on the surface,
the protrusion comprises a convex protrusion,
at least a portion the cover is comprised of a sufficiently rigid material to cause tissue of the wearer to conform to at least a portion of a shape of the cover,
the cover is further configured to cover the wall, and
the wall operably connects to the substrate on one side and operably connects to the cover on an opposite side;
one or more openings that allow light to pass through to the photodiodes of the first and second pluralities of photodiodes;
a touch-screen display;
a strap configured to facilitate attachment of at least part of the multi-channel physiological parameter measurement device to an arm of the wearer; and
one or more processors configured to:
receive information responsive to at least one of the first detector channel or the second detector channel;
process the information to determine physiological parameter measurement information;
cause communication of the physiological parameter measurement information to a user interface displayed on the touch-screen display; and
cause transmission of the physiological parameter measurement information to at least one of: a mobile phone, or a computer network.
2. A multi-channel physiological parameter measurement device comprising:
one or more light emitters;
a substrate having a surface;
a first plurality of photodiodes arranged on the surface and configured to provide a first detector channel, wherein:
the first plurality of photodiodes consisting of four photodiodes, and
the photodiodes of the first plurality of photodiodes together provide the first detector channel responsive to light from at least one of the one or more light emitters attenuated by body tissue;
a second plurality of photodiodes arranged on the surface and configured to provide a second detector channel, wherein:
the second plurality of photodiodes consisting of four photodiodes,
the photodiodes of the second plurality of photodiodes together provide the second detector channel responsive to light from at least one of the one or more light emitters attenuated by body tissue, and
at least one of the first detector channel or the second detector channel includes information usable to determine a physiological parameter of a wearer of the multi-channel physiological parameter measurement device;
a wall extending from the surface and configured to surround at least the first and second pluralities of photodiodes; and
an at least partially opaque cover arranged to cover at least a portion of the surface of the substrate, wherein the cover comprises a protrusion that extends over all of the photodiodes of the first and second pluralities of photodiodes arranged on the surface, wherein the cover is further configured to cover the wall, wherein the cover includes a plurality of separate windows corresponding to each of the photodiodes of the first and second pluralities of photodiodes, and wherein the cover, the wall, and the substrate together create one or more gaps in which the photodiodes of the first and second pluralities of photodiodes are positioned and sealed.
3. The multi-channel physiological parameter measurement device of claim 2 further comprising preprocessing electronics including at least:
first preprocessing electronics configured to preprocess the first detector channel; and
second preprocessing electronics configured to preprocess the second detector channel.
4. The multi-channel physiological parameter measurement device of claim 3 , wherein:
the first preprocessing electronics comprise at least a first amplifier configured to receive the first detector channel and at least amplify the first detector channel, and
the second preprocessing electronics comprise at least a second amplifier configured to receive the second detector channel and at least amplify the second detector channel.
5. The multi-channel physiological parameter measurement device of claim 4 , wherein the preprocessing further comprises converting at least one of the first detector channel or the second detector channel from analog to digital.
6. The multi-channel physiological parameter measurement device of claim 4 , wherein the protrusion comprises a convex protrusion, and wherein at least a portion the cover is comprised of a sufficiently rigid material to cause tissue of the wearer to conform to at least a portion of a shape of the cover.
7. The multi-channel physiological parameter measurement device of claim 6 , wherein the physiological parameter comprises at least one of: pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.
8. The multi-channel physiological parameter measurement device of claim 7 , wherein at least part of the cover is light permeable.
9. The multi-channel physiological parameter measurement device of claim 8 further comprising:
a touch-screen display;
a strap configured to facilitate attachment of at least part of the multi-channel physiological parameter measurement device to an arm of the wearer; and
one or more processors configured to:
receive information responsive to at least one of the first detector channel or the second detector channel;
process the information to determine physiological parameter measurement information; and
cause communication of the physiological parameter measurement information to a user interface displayed on the touch-screen display.
10. The multi-channel physiological parameter measurement device of claim 9 , wherein the one or more processors are further configured to:
process the information to determine bulk measurement to confirm correct positioning of the multi-channel physiological parameter measurement device.
11. The multi-channel physiological parameter measurement device of claim 9 , wherein the one or more processors are further configured to:
process the information to determine light piping.
12. The multi-channel physiological parameter measurement device of claim 9 , wherein the attenuated light is reflected by the tissue.
13. The multi-channel physiological parameter measurement device of claim 12 , wherein the one or more processors are further configured to:
cause transmission of the physiological parameter measurement information to at least one of: a mobile phone, or a computer network.
14. The multi-channel physiological parameter measurement device of claim 13 further comprising:
a magnet configured to be used as a connecting mechanism.
15. The multi-channel physiological parameter measurement device of claim 14 , further comprising a third detector channel and a fourth detector channel.
16. A multi-channel physiological parameter measurement device comprising:
a plurality of light emitters configured to emit light into tissue of a user;
a first plurality of photodiodes configured to provide a first detector channel, the first plurality of photodiodes comprising at least four photodiodes, the photodiodes of the first plurality of photodiodes together providing the first detector channel responsive to light from at least one of the plurality of light emitters attenuated by the tissue, wherein each of the photodiodes of the first plurality of photodiodes has a corresponding window that allows light to pass through to the photodiode;
a second plurality of photodiodes configured to provide a second detector channel, the second plurality of photodiodes comprising at least four photodiodes, the photodiodes of the second plurality of photodiodes together providing the second detector channel responsive to light from at least one of the plurality of light emitters attenuated by the tissue, wherein each of the photodiodes of the second plurality of photodiodes has a corresponding window that allows light to pass through to the photodiode;
a protrusion that extends over the photodiodes of the first and second pluralities of photodiodes;
preprocessing electronics including at least:
first preprocessing electronics configured to preprocess the first detector channel; and
second preprocessing electronics configured to preprocess the second detector channel; and
one or more processors configured to:
receive information responsive to at least one of the first detector channel or the second detector channel after the preprocessing of the at least one of the first detector channel or the second detector channel, wherein the information is responsive to at least a physiological parameter of the user; and
process the information to determine measurements of the physiological parameter.
17. The multi-channel physiological parameter measurement device of claim 16 , wherein the first and second pluralities of photodiodes are arranged on a substrate, and wherein the protrusion extends over at least a part of the substrate.
18. The multi-channel physiological parameter measurement device of claim 17 , wherein:
the first preprocessing electronics comprise at least a first amplifier configured to receive the first detector channel and at least amplify the first detector channel, and
the second preprocessing electronics comprise at least a second amplifier configured to receive the second detector channel and at least amplify the second detector channel.
19. The multi-channel physiological parameter measurement device of claim 18 , wherein the preprocessing further comprises converting at least one of the first detector channel or the second detector channel from analog to digital.
20. The multi-channel physiological parameter measurement device of claim 18 , wherein the protrusion comprises a convex protrusion, and wherein at least a portion the convex protrusion is comprised of a sufficiently rigid material to cause tissue of the user of the multi-channel physiological parameter measurement device to conform to at least a portion of a shape of the convex protrusion when the multi-channel physiological parameter measurement device is worn by the user.
21. The multi-channel physiological parameter measurement device of claim 20 , wherein the physiological parameter comprises at least one of: pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.
22. The multi-channel physiological parameter measurement device of claim 21 , wherein at least part of the protrusion is light permeable.
23. The multi-channel physiological parameter measurement device of claim 22 further comprising:
a strap configured to facilitate attachment of at least part of the multi-channel physiological parameter measurement device to an arm of the user; and
a touch-screen display,
wherein the one or more processors are further configured to cause communication of the physiological parameter measurement information to a user interface displayed on the touch-screen display.
24. The multi-channel physiological parameter measurement device of claim 23 , wherein the attenuated light is reflected by the tissue.
25. The multi-channel physiological parameter measurement device of claim 24 , wherein the one or more processors are further configured to:
cause transmission of the physiological parameter measurement information to at least one of: a mobile phone, or a computer network.
26. A physiological measurement system comprising:
a multi-channel physiological parameter measurement device according to claim 25 ; and
a mobile phone configured to wireles sly communicate with the multi-channel physiological parameter measurement device.