Granted Patent
B2
US 10,858,306 · App. 16/844,077 · Granted Dec 8, 2020
Method for synthesizing iodo- or astatoarenes using diaryliodonium salts
Inventors:
François Guerard (Nantes, FR); Jean-François Gestin (Nantes, FR); Martin W. Brechbiel (Bethesda, MD); Yong-Sok Lee (Bethesda, MD)
Assignees:
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE NANTES; UNIVERSITE D'ANGERS; THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
C07C201/12C07B59/001C07B59/002C07B59/008C07C17/361C07C25/24C07C29/10C07C29/58C07C29/62C07C33/46C07C41/18C07C43/225C07C67/307C07C247/10C07C247/16C07C253/30C07D207/46C07B2200/05
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Abstract
The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.
Claims (2)
1. An astatoarene having one of the following formulae:
2. A diaryliodonium salt having one of the following formulae:
Assignments (1)
MERGER
Recorded Sep 7, 2023
From: UNIVERSITE DE NANTES
To: NANTES UNIVERSITE
Reel/Frame 064824/0596 →