IP Library Granted Patent US 10,881,880
Granted Patent B2
US 10,881,880 · App. 16/846,227 · Granted Jan 5, 2021

Radiation detector calibration

Inventors: Amir Ramezanzadeh Moghadam (Melbourne, FL); Jakub Kozelka (Melbourne, FL)
Assignee: SUN NUCLEAR CORPORATION
A61N5/1075A61B5/055A61N5/1049A61N5/1045A61N5/1071A61N2005/1054
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Quick Facts
Patent No.
US 10,881,880
App. No.
16/846,227
Granted
Jan 5, 2021
Kind
B2
Abstract

A computer program product, method, system and device that acquires, by a radiation detector, exit radiation measurement information during delivery of patient treatment. Patient anatomy information is also received and a radiation detector response calibration is determined utilizing at least the exit radiation measurement information, the patient anatomy information, and at least a portion of a radiation treatment plan.

Claims (32)

1. A system comprising:

at least one programmable processor; and

a non-transitory machine-readable medium storing instructions which, when executed by the at least one programmable processor, cause the at least one programmable processor to perform operations comprising:

receiving at least a portion of a radiation treatment plan;

acquiring, by a radiation detector, exit radiation measurement information during delivery of patient treatment;

deriving a measured collimator profile from the exit radiation measurement information;

determining at least one estimated collimator profile from at least a portion of the radiation treatment plan and an approximate image start time and an approximate image end time; and

comparing the measured collimator profile with at least one estimated collimator profile to determine an image start time and an image end time.

2. The system of claim 1 , wherein the radiation detector is an EPID.

3. The system of claim 1 , wherein the measured collimator profile and/or the estimated collimator profile comprise a boundary of an aperture formed by leaves of the collimator.

4. The system of claim 1 , the at least one programmable processor further configured to perform operations comprising determining the start and end times by at least determining a best match between the measured collimator profile and more than one estimated collimator profile to determine a best matched collimator profile.

5. The system of claim 4 , the at least one programmable processor further configured to perform operations comprising determining the best match by at least minimizing the distance between boundaries of the estimated collimator profile and the measured collimator profile.

6. The system of claim 4 , the at least one programmable processor further configured to perform operations comprising:

calculating a difference between the measured collimator profile and the best matched collimator profile; and

increasing, in response to the difference exceeding a predetermined value, a range of times for the image start time and the image end time used to calculate the more than one estimated collimator profiles.

7. The system of claim 1 , wherein the image start time and image end time correspond to times from the radiation treatment plan.

8. The system of claim 1 , the at least one programmable processor further configured to perform operations comprising determining a patient entrance fluence utilizing the portion of the radiation treatment plan and the image start time and image end time.

9. A computer program product comprising a non-transitory, machine-readable medium storing instructions which, when executed by at least one programmable processor, cause the at least one programmable processor to perform operations comprising:

receiving at least a portion of a radiation treatment plan;

acquiring, by a radiation detector, exit radiation measurement information during delivery of patient treatment;

deriving a measured collimator profile from the exit radiation measurement information;

determining at least one estimated collimator profile from at least a portion of the radiation treatment plan and an approximate image start time and an approximate image end time; and

comparing the measured collimator profile with at least one estimated collimator profile to determine an image start time and an image end time.

10. The computer program product of claim 9 , wherein the radiation detector is an EPID.

11. The computer program product of claim 9 , wherein the measured collimator profile and/or the estimated collimator profile comprise a boundary of an aperture formed by leaves of the collimator.

12. The computer program product of claim 9 , the operations further comprising determining the start and end times by at least determining a best match between the measured collimator profile and more than one estimated collimator profile to determine a best matched collimator profile.

13. The computer program product of claim 12 , the operations further comprising determining the best match by at least minimizing the distance between boundaries of the estimated collimator profile and the measured collimator profile.

14. The computer program product of claim 12 , the operations further comprising:

calculating a difference between the measured collimator profile and the best matched collimator profile; and

increasing, in response to the difference exceeding a predetermined value, a range of times for the image start time and the image end time used to calculate the more than one estimated collimator profiles.

15. The computer program product of claim 9 , wherein the image start time and image end time correspond to times from the radiation treatment plan.

16. The computer program product of claim 9 , the at least one programmable processor further configured to perform operations comprising determining a patient entrance fluence utilizing the portion of the radiation treatment plan and the image start time and image end time.

Assignments (4)
SECURITY INTEREST Recorded Oct 22, 2021
From: MIRION TECHNOLOGIES (HOLDINGSUB2), LTD.; MIRION TECHNOLOGIES (USHOLDINGS), INC.; MIRION TECHNOLOGIES (US), INC.; MIRION TECHNOLOGIES (CANBERRA), INC.; MIRION TECHNOLOGIES (CONAX NUCLEAR), INC.; SUN NUCLEAR CORP.; GAMMEX, INC.; MIRION TECHNOLOGIES (IST) CORPORATION; BIODEX MEDICAL SYSTEMS, INC.; MIRION TECHNOLOGIES (CAPINTEC), INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 057890/0509 →
RELEASE OF SECURITY INTEREST Recorded Oct 22, 2021
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: MIRION TECHNOLOGIES (RADOS) GMBH; MIRION TECHNOLOGIES (CANBERRA UK) LTD.; MIRION TECHNOLOGIES (CANBERRA) SAS; MIRION TECHNOLOGIES (CANBERRA), INC.; MIRION TECHNOLOGIES (CANBERRA), INC. (F/K/A CANBERRA INDUSTRIES, INC.); MIRION TECHNOLOGIES (CANBERRA) INC. (F/K/A MIRION TECHNOLOGIES (IMAGING), LLC); MIRION TECHNOLOGIES (IST) CORPORATION; MIRION TECHNOLOGIES, INC.; BIODEX MEDICAL SYSTEMS, INC.; GAMMEX, INC.; SUN NUCLEAR CORP.
Reel/Frame 057890/0970 →
SECURITY AGREEMENT Recorded Jan 6, 2021
From: SUN NUCLEAR CORP.; GAMMEX, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 054912/0663 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2020
From: RAMEZANZADEH MOGHADAM, AMIR; KOZELKA, JAKUB
To: SUN NUCLEAR CORPORATION
Reel/Frame 052383/0426 →
Continuity (2)
Continuation 14694865 · Apr 23, 2015
Related Publication 20200238104A1 · Jul 30, 2020