METHOD FOR THE TREATMENT OR PREVENTION OF INFECTION-RELATED IMMUNE CONDITIONS USING A COMPOSITION COMPRISING IGM
Embodiments of the present invention provide methods for the treatment or prevention of infection-related immune conditions using compositions comprising IgM.
1 - 52 . (canceled)
53 . A composition comprising IgM.
54 . The composition according to claim 53 , characterized in that the composition used has at least 90% (w/v) of IgM purity.
55 . The composition according to claim 53 , characterized in that the composition has a 95% (w/v) of IgM purity.
56 . The composition according to claim 53 , characterized in that IgM is recombinant.
57 . The composition according to claim 53 , characterized in that IgM is plasma-derived.
58 . The composition according to claim 53 , characterized in that IgM is cell culture-derived.
59 . The composition according to claim 53 , characterized in that IgM is transgenic.
60 . The composition according to claim 53 , characterized in that IgM is or chemically synthesized.
61 . The composition according to claim 57 , wherein IgM is plasma-derived IgM and is isolated from a suitable fraction of plasma.
62 . The composition according to claim 53 , characterized in that the composition further comprises one or more anti-inflammatory molecules, small molecule antibiotics, molecules that are antimicrobial in nature, natural or synthetic peptide antimicrobials, proteins with antimicrobial properties, other immunomodulators or combinations thereof.
63 . The composition according to claim 62 , hat the composition further comprises vancomycin, meropenem, lactoferrin or combinations thereof.