IP Library Granted Patent US 11,576,714
Granted Patent B2
US 11,576,714 · App. 16/861,443 · Granted Feb 14, 2023

Contact sensing systems and methods

Inventors: Dorin Panescu (San Jose, CA); Jessi E Johnson (Sunnyvale, CA)
Assignee: Epix Therapeutics, Inc.
A61B18/1206A61B5/01A61B5/0538A61B18/1492A61B5/742A61B5/7455A61B2018/00791A61B2018/00869A61B2018/00875A61B2018/00904A61B2018/128A61B2090/065A61B2218/002
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Quick Facts
Patent No.
US 11,576,714
App. No.
16/861,443
Granted
Feb 14, 2023
Kind
B2
Abstract

According to some embodiments, a medical instrument comprises an elongate body having a proximal end and a distal end and a pair of electrodes or electrode portions (for example, a split-tip electrode assembly). Systems and methods are described herein that perform contact sensing and/or ablation confirmation based on electrical measurements obtained while energy of different frequencies are applied to the pair of electrodes or electrode portions. The contact sensing systems and methods may calibrate network parameter measurements to compensate for a hardware unit in a network parameter measurement circuit or to account for differences in cables, instrumentation or hardware used.

Claims (24)

1. A system for determining whether a medical instrument is in contact with tissue based, at least in part, on impedance measurements, the system comprising:

a signal source configured to deliver signals having different frequencies to a pair of electrodes of a medical instrument; and

a processing device configured to:

apply a transform to a resulting waveform that formulates across the pair of electrodes to obtain impedance measurements at a first frequency and a second frequency;

determine a ratio between the magnitude of the impedance at the second frequency and the first frequency; and

generate an output indicative of contact based on the ratio.

2. The system of claim 1 , wherein the signal source comprises a radiofrequency energy source and wherein the first and second frequencies are between 5 kHz and 1000 kHz.

3. The system of claim 1 , wherein the signal source is configured to generate signals having a frequency adapted for tissue ablation.

4. The system of claim 1 , further comprising a second signal source configured to generate signals having a frequency adapted for tissue ablation.

5. The system of claim 4 , wherein the frequency adapted for tissue ablation is between 400 kHz and 600 kHz.

6. A method of determining whether a medical instrument is in contact with tissue based, at least in part, on impedance measurements, the method comprising:

applying signals having a first frequency and a second frequency to a pair of electrodes of medical instrument; applying a transform to a resulting waveform to obtain impedance measurements at the first frequency and the second frequency;

determining a ratio between the magnitude of the impedance at the second frequency and the first frequency; and

generating an output indicative of contact based on the ratio.

7. The method of claim 6 , wherein the first frequency and the second frequency are within a range between 5 kHz and 1000 kHz.

8. The method of claim 6 , wherein the second frequency is higher than the first frequency.

9. The method of claim 6 , wherein impedance measurements at the first frequency and the second frequency are obtained sequentially.

10. The method of claim 6 , wherein impedance measurements at the first frequency and the second frequency are obtained simultaneously.

11. The method of claim 6 , wherein the second frequency is at least 20 kHz higher than the first frequency.

12. The method of claim 6 , wherein the first frequency is 20 kHz and the second frequency is 800 kHz.

13. The method of claim 6 , wherein the output comprises textual information indicative of contact.

14. The method of claim 6 , wherein the output comprises a quantitative measurement indicative of contact.

15. The method of claim 6 , wherein the output comprises a qualitative assessment of contact.

16. The method of claim 6 , wherein the transform is a Fourier transform.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 14, 2020
From: PANESCU, DORIN; JOHNSON, JESSI E.
To: ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 054046/0391 →
SECURITY INTEREST Recorded Oct 14, 2020
From: ADVANCED CARDIAC THERAPEUTICS, INC.
To: ABBOTT LABORATORIES
Reel/Frame 054046/0453 →
CHANGE OF NAME Recorded Oct 14, 2020
From: ADVANCED CARDIAC THERAPEUTICS, INC.
To: EPIX THERAPEUTICS, INC.
Reel/Frame 054046/0544 →
RELEASE BY SECURED PARTY Recorded Oct 14, 2020
From: ABBOTT LABORATORIES
To: EPIX THERAPEUTICS, INC., FORMERLY ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 054074/0255 →
Continuity (7)
Continuation 15582197 · Apr 28, 2017
Continuation 15179689 · Jun 10, 2016
Continuation PCTUS2015061311 · Nov 18, 2015
Provisional Application 62243289 · Oct 19, 2015
Provisional Application 62195717 · Jul 22, 2015
Provisional Application 62138338 · Mar 25, 2015
Related Publication 20200261142A1 · Aug 20, 2020