IP Library Granted Patent US 11,058,683
Granted Patent B2
US 11,058,683 · App. 16/863,821 · Granted Jul 13, 2021

Treating sexual desire disorders with flibanserin

Inventors: Franco Borsini (Baden Württemberg, DE); Kenneth Robert Evans (Toronto, CA)
Assignee: Sprout Pharmaceuticals, Inc.
A61K31/496
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Quick Facts
Patent No.
US 11,058,683
App. No.
16/863,821
Granted
Jul 13, 2021
Kind
B2
Abstract

The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.

Claims (22)

1. A method of treating acquired hypoactive sexual desire disorder in a human adult female patient, wherein the acquired sexual desire disorder is not drug-induced, comprising orally administering a therapeutically effective amount of flibanserin or a pharmaceutically acceptable acid addition salt thereof to the patient to treat the acquired hypoactive sexual desire disorder.

2. The method according to claim 1 , wherein the amount administered is between about 1 mg and 300 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

3. The method according to claim 1 , wherein the amount administered is in a dosage unit containing about 100 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

4. A method of treating acquired hypoactive sexual desire disorder in a human adult female patient, wherein the acquired sexual desire disorder is not drug-induced, comprising orally administering a tablet comprising a therapeutically effective amount of flibanserin to the human adult female patient to treat the female hypoactive sexual desire disorder.

5. The method according to claim 4 , wherein the tablet comprises about 1 mg and 300 mg per day of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

6. The method according to claim 4 , wherein the tablet comprises about 100 mg of flibanserin or a pharmaceutically acceptable acid addition salt thereof.

7. The method according to claim 1 , wherein the amount administered is in a dosage unit, the dosage unit further comprising one or more excipients or carriers, selected from the group consisting of an inert diluent, a lubricant, a disintegrant, a binder, an agent for delaying release, a sweetener, a flavor enhancer, a preservative, or any combination thereof.

8. The method according to claim 4 , wherein the tablet further comprises one or more excipients or carriers selected from the group consisting of an inert diluent, a lubricant, a disintegrant, a binder, an agent for delaying release, a sweetener, a flavor enhancer, a preservative, or any combination thereof.

9. The method according to claim 7 , wherein the inert diluent is selected from calcium carbonate, calcium phosphate, lactose, and combinations thereof.

10. The method according to claim 8 , wherein the inert diluent is selected from calcium carbonate, calcium phosphate, lactose, and combinations thereof.

11. The method according to claim 7 , wherein the lubricant is selected from the group consisting of magnesium stearate, talc, and combinations thereof.

12. The method according to claim 8 , wherein the lubricant is selected from the group consisting of magnesium stearate, talc, and combinations thereof.

13. The method according to claim 7 , wherein the disintegrant is selected from corn starch, alginic acid, and combinations thereof.

14. The method according to claim 8 , wherein the disintegrant is selected from corn starch, alginic acid, and combinations thereof.

15. The method according to claim 7 , wherein the binder is selected from starch, gelatin, and combinations thereof.

16. The method according to claim 8 , wherein the binder is selected from starch, gelatin, and combinations thereof.

17. The method according to claim 7 , wherein the agent for delaying release is selected from carboxymethyl cellulose, cellulose acetate phthalate, polyvinyl acetate, and combinations thereof.

18. The method according to claim 8 , wherein the agent for delaying release is selected from carboxymethyl cellulose, cellulose acetate phthalate, polyvinyl acetate, and combinations thereof.

19. The method according to claim 7 , wherein the dosage form further comprises one or more sweeteners, one or more flavor enhancers, preservatives, or a combination thereof.

20. The method according to claim 8 , wherein the tablet further comprises one or more sweeteners, one or more flavor enhancers, preservatives, or a combination thereof.

21. The method according to claim 7 , wherein the dosage form further comprises magnesium stearate, talc, microcrystalline cellulose, lactose, sodium-carboxymethyl starch, or any combination thereof.

22. The method according to claim 8 , wherein the tablet further comprises magnesium stearate, talc, microcrystalline cellulose, lactose, sodium-carboxymethyl starch, or any combination thereof.

Assignments (1)
SECURITY INTEREST Recorded Feb 25, 2021
From: SPROUT PHARMACEUTICALS, INC.
To: GOODRICH, BRAXTON; WHITEHEAD, ROBERT
Reel/Frame 055407/0810 →