IP Library Granted Patent US 11,536,645
Granted Patent B2
US 11,536,645 · App. 16/871,516 · Granted Dec 27, 2022

Detecting backscatter from drops dispensed from a handheld dropper and associated systems, devices, and methods

Inventors: Dimitri Azar (San Francisco, CA); Supriyo Sinha (Menlo Park, CA)
Assignee: VERILY LIFE SCIENCES LLC
G01N15/1434A61F9/0008G01N15/1456A61M5/1689A61M2205/3306
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Quick Facts
Patent No.
US 11,536,645
App. No.
16/871,516
Granted
Dec 27, 2022
Kind
B2
Abstract

Devices, systems, and associated methods for detecting drops dispensed by a dropper are provided. For example, a drop detection device may include a light source and a light detector configured to be coupled to a drop dispenser such that the light source and light detector are disposed proximal of a distal dispensing tip of the drop dispenser. The light detector may be configured to receive a reflected portion of a beam of light from the light source, which is reflected by a drop dispensed through the dispensing tip of the drop dispenser. In some embodiments, a processing circuit is configured to analyze a signal provided by the light detector to detect the dispensed drop.

Claims (45)

1. A device for detecting a drop dispensed by a drop dispenser, comprising:

a housing configured to couple to the drop dispenser;

a light source coupled to the housing and configured to emit a beam of light toward the drop dispensed by the drop dispenser;

a processing circuit; and

a light detector coupled to the housing and in communication with the processing circuit,

the light detector configured to:

receive a portion of the beam of light reflected by the drop; and

provide, to the processing circuit, a signal indicating an amount of reflected light received over a period of time,

wherein the processing circuit is configured to detect the drop based on the signal,

wherein the light source and the light detector are disposed on a distal-facing surface of the housing, wherein the distal-facing surface of the housing is arranged perpendicularly to a dispensing axis of the drop dispenser and is proximal to a distal end of the drop dispenser when the drop dispenser is coupled to the housing; and,

wherein the light source and the light detector are coupled to the housing such that, when the housing is coupled to the drop dispenser:

the light source is oriented to emit the beam of light along a first axis at a first oblique angle relative to the dispensing axis of the drop dispenser, and

the light detector is oriented to receive the portion of the beam of light along a second axis at a second oblique angle relative to the dispensing axis of the drop dispenser, wherein the second oblique angle is non-parallel to the first oblique angle.

2. The device of claim 1 , wherein the light source comprises at least one of a laser diode and a light-emitting diode.

3. The device of claim 1 , wherein the light detector comprises a photodiode.

4. The device of claim 1 , wherein the light detector comprises a bandpass filter and a focusing lens.

5. The device of claim 1 , wherein the first axis, the second axis, and the dispensing axis intersect at an interrogation point located distally of a dispensing tip of the drop dispenser.

6. The device of claim 1 , wherein the housing is configured to engage a lip of the drop dispenser.

7. The device of claim 6 , wherein the housing is coupled to the drop dispenser such that a cap of the drop dispenser can be removed and replaced without removing the drop dispenser.

8. The device of claim 1 , wherein the processing circuit is configured to detect the drop by determining that an amplitude of the signal exceeds a threshold for a predetermined amount of time.

9. A method for detecting a drop dispensed by a drop dispenser, including:

emitting, by a light source disposed on a distal-facing surface of the drop dispenser, a beam of light toward the drop, wherein the light source is oriented to emit the beam of light along a first axis at a first oblique angle relative to a dispensing axis of the drop dispenser, wherein the distal-facing surface is arranged perpendicularly to the dispensing axis of the drop dispenser and is proximal to a distal end of the drop dispenser;

receiving, by a light detector disposed on the distal-facing surface of the drop dispenser, a portion of the beam of light reflected by the drop, wherein the light detector is oriented to receive a portion of the beam of light along a second axis at a second oblique angle relative to the dispensing axis of the drop dispenser, wherein the second oblique angle is non-parallel to the first oblique angle;

providing, by the light detector, a signal indicating an amount of reflected light received by the light detector over a period of time; and

analyzing, by a processing component in communication with the light detector, the signal to detect the drop.

10. The method of claim 9 , wherein emitting the beam of light comprises emitting the beam of light using at least one of a laser diode or a light-emitting diode.

11. The method of claim 9 , wherein receiving the portion of the beam of light comprises receiving the portion of the beam of light using a photodiode.

12. The method of claim 9 , wherein the light detector comprises a bandpass filter and a focusing lens.

13. The method of claim 9 , wherein the first axis, the second axis, and the dispensing axis intersect at an interrogation point located distally of a dispensing tip of the drop dispenser.

14. The method of claim 9 , wherein analyzing the signal to detect the drop comprises determining that an amplitude of the signal exceeds a threshold for a predetermined amount of time.

15. A device for detecting a drop dispensed by a drop dispenser, comprising:

a housing configured to couple to the drop dispenser;

a light source coupled to the housing and configured to emit a beam of light toward the drop dispensed by the drop dispenser;

a processing circuit; and

a light detector coupled to the housing and in communication with the processing circuit, the light detector configured to:

receive a portion of the beam of light reflected by the drop: and

provide, to the processing circuit, a signal indicating an amount of reflected light received over a period of time,

wherein the processing circuit is configured to detect the drop based on the signal,

wherein the light source and the light detector are coupled to a lip of the housing and are located on a plane perpendicular to a dispensing axis,

wherein, during measurement of the drop, the light source and the light detector are above a dispensing tip and are configured to detect the drop when the drop is below the dispensing tip

wherein the light source and the light detector are coupled to the lip of the housing such that, when the housing is coupled to the drop dispenser:

the light source is oriented to emit the beam of light along a first axis at a first oblique angle relative to the dispensing axis of the drop dispenser, and

the light detector is oriented to receive the portion of the beam of light along a second axis at a second oblique angle relative to the dispensing axis of the drop dispenser, wherein the second oblique angle is non-parallel to the first oblique angle.

16. The device of claim 15 , wherein the first axis, the second axis, and the dispensing axis intersect at an interrogation point located below the dispensing tip of the drop dispenser.

17. The device of claim 15 , wherein the housing is configured to engage a lip of the drop dispenser.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2024
From: TWENTY TWENTY THERAPEUTICS LLC
To: VERILY LIFE SCIENCES LLC
Reel/Frame 069113/0638 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2023
From: VERILY LIFE SCIENCES LLC
To: TWENTY TWENTY THERAPEUTICS LLC
Reel/Frame 062820/0978 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 7, 2020
From: VERILY LIFE SCIENCES LLC
To: TWENTY TWENTY THERAPEUTICS LLC
Reel/Frame 054358/0304 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 19, 2020
From: AZAR, DIMITRI; SINHA, SUPRIYO
To: VERILY LIFE SCIENCES LLC
Reel/Frame 052706/0207 →
Continuity (2)
Provisional Application 62847179 · May 13, 2019
Related Publication 20200363313A1 · Nov 19, 2020