Granted Patent
B2
US 11,021,515 · App. 16/871,777 · Granted Jun 1, 2021
Therapeutically active compounds and their methods of use
Inventors:
Rene M. Lemieux (Charlestown, MA); Janeta Popovici-Muller (Windham, NH); Jeremy Travins (Southborough, MA); Zhenwei Cai (Princeton, NJ); Dawei Cui (Shanghai, CN); Ding Zhou (Shanghai, CN)
Assignee:
Agios Pharmaceuticals, Inc.
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Abstract
Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.
Claims (2)
1. A method for treating Ollier disease comprising administering to a patient in need thereof a compound of formula:
or a pharmaceutically acceptable salt, tautomer, isotopologue or hydrate thereof.
Assignments (6)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME SERVIER PHARMACEUTICALS LLC BY REMOVAL OF COMMA AND UPDATING ZIP CODE TO 02210 PREVIOUSLY RECORDED ON REEL 056224 FRAME 0921. ASSIGNOR(S) HEREBY CONFIRMS THE CORRECTIVE ASSIGNMENT.
Recorded Oct 28, 2021
From: AGIOS PHARMACEUTICALS, INC.
To: SERVIER PHARMACEUTICALS LLC
Reel/Frame 057970/0314 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NO. 10,172,864 TO THE CORRECT APP NO. 61/160,253 PREVIOUSLY RECORDED ON REEL 056179 FRAME 0417. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT.
Recorded May 12, 2021
From: AGIOS PHARMACEUTICALS, INC.
To: SERVIER PHARMACEUTICALS, LLC
Reel/Frame 056224/0921 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded May 7, 2021
From: AGIOS PHARMACEUTICALS, INC.
To: SERVIER PHARMACEUTICALS, LLC
Reel/Frame 056179/0417 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 3, 2021
From: LEMIEUX, RENE M.; POPOVICI-MULLER, JANETA; TRAVINS, JEREMY
To: AGIOS PHARMACEUTICALS, INC.
Reel/Frame 055480/0443 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 3, 2021
From: CAI, ZHENWEI; CUI, DAWEI; ZHOU, DING
To: PHARMARESOURCES (SHANGHAI) CO., LTD.
Reel/Frame 055485/0842 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 3, 2021
From: PHARMARESOURCES (SHANGHAI) CO., LTD.
To: AGIOS PHARMACEUTICALS, INC.
Reel/Frame 055485/0848 →
Priority Claims (2)
WO PCT/CN2013/080105
· Jul 25, 2013
· international
WO PCT/CN2014/082869
· Jul 24, 2014
· international
Continuity (4)