IP Library › Patent Application 16882656
Patent Application
App. No. 16/882,656

PEPTIDE COMPOSITIONS AND RELATED METHODS

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
16/882,656
Abstract

Peptide compositions and methods for inhibiting neovascularization or development of pathological or aberrant blood vessels in human or other animal subjects.

Claims (29)

1 . A composition of matter comprising a peptide which consists of or includes an amino acid sequence having the formula

Y—X—Z

wherein:

Y=R, H, K, Cys(acid), G or D;

X=G, A, Cys(acid), R, G, D or E; and

Z=Cys(acid), G, C, R, D, N or E.

2 . (canceled)

3 . (canceled)

4 . (canceled)

5 . A composition according to claim 2 wherein the peptide comprises R-G-Cys(acid)-G-G-G-D-G.

6 . A composition according to claim 2 wherein the peptide comprises Cyclo-{R-G-Cys(acid)-F-N-Me-V}.

7 . A composition according to claim 1 wherein the amino acid sequence is R-A-Cys (acid).

8 . A composition according to claim 1 wherein the amino acid sequence is R-G-Cysteine.

9 . A composition according to claim 1 wherein the amino acid sequence is R-Cys(acid)-G.

10 . A composition according to claim 1 wherein the amino acid sequence is Cys(acid)-R-G.

11 . A composition according to claim 1 wherein the amino acid sequence is Cys(acid)-G-R.

12 . A composition according to claim 1 wherein the amino acid sequence is R-G-D.

13 . A composition according to claim 12 wherein the peptide comprises Cyclo-{R-G-D-D-F-NMe-V}.

14 . A composition according to claim 1 wherein the amino acid sequence is H-G-Cys(acid).

15 . A composition according to claim 1 wherein the amino acid sequence is R-G-N.

16 . A composition according to claim 1 wherein the amino acid sequence is D-G-R.

17 . A composition according to claim 1 wherein the amino acid sequence is R-D-G.

18 . A composition according to claim 1 wherein the amino acid sequence is R-A-E.

19 . A composition according to claim 1 wherein the amino acid sequence is K-G-D.

20 . A composition according to any of claims 1 through 19 wherein the peptide comprises a salt.

21 . A composition according to claim 20 wherein the salt is selected from trifluoroacetate, acetate and hydrochloride salt forms.

22 . A composition according to any of claims 1 through 19 further comprising taurine.

23 . A composition comprising G-R-G-Cys(acid)-T-P or a salt thereof in combination with Taurine.

24 .- 29 . (canceled)

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2024
From: ALLEGRO PHARMACEUTICALS, L.L.C.
To: JENIUS PHARMA, LLC
Reel/Frame 067376/0103 →