Intravascular Devices And Delivery Systems And Uses Thereof
In general, the invention features an intravascular device, a delivery system, and methods for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels The intravascular device of the invention may prevent passage of a particle in a blood vessel from passing through a filter supported by a frame, upper and lower stabilizers, and a wire. The wire may be used to stabilize the device upon its deployment and installation within a blood vessel. Further, in some embodiments, the invention features a delivery system and methods for introduction of the device into a blood vessel.
1 . An intravascular device for deflecting emboli comprising:
a frame having a length;
an embolic filter attached to and extending the length of the frame;
a wire configured to run along the length of said filter from a proximal portion to a distal portion, wherein a distal end of the wire extends further than a distal end of the frame; and,
wherein the frame is connected to the wire by a connector extending between a proximal end of the frame and a point on the wire proximal of the proximal end of the filter.
2 . The device of claim 1 , wherein the wire is arranged to exert a force on at least one of the frame and the filter when deployed in an aorta of a subject.
3 . The device of claim 1 , wherein the frame is attached to the wire only at the proximal portion of the frame.
4 . The device of claim 1 , wherein the frame defines the shape of the filter and the frame is suitable to be held in contact with both an ascending and a descending aorta.
5 . The device of claim 1 , wherein the wire is configured to exert a force upward from a horizontal plane of the filter.
6 . The device of claim 1 , wherein the wire comprises at least one lumen.
7 . The device of claim 6 , further comprising a guide wire positioned within the at least one lumen.
8 . The device of claim 1 , wherein the wire comprises an attached protected lip.
9 . The device of claim 1 , wherein the wire comprises a dilator tip.
10 . A system comprising:
an intravascular device for deflecting emboli comprising:
a frame having a length;
an embolic filter attached to and extending the length of the frame;
a wire configured to run along the length of said filter from a proximal portion to a distal portion, and wherein a distal end of the wire extends further than a distal end of the frame; and
wherein the frame is connected to the wire by a connector extending between a proximal end of the frame and a point on the wire proximal of the proximal end of the filter; and,
an introducer sheath having a lumen for introduction of the intravascular device to an aorta of a subject.
11 . The system of claim 10 , wherein the introducer sheath comprises a braided or coiled material.
12 . The system of claim 10 , further comprising a deflector.
13 . The system of claim 10 , further comprising a pigtail catheter.
14 . The system of claim 13 , wherein the pigtail catheter further comprises a blunted tip.
15 . The system of claim 13 , wherein the pigtail catheter, the wire, and the device are loaded into a single lumen of the introducer sheath.
16 . An intravascular device for deflecting emboli comprising:
a frame having a length;
an embolic filter attached to and extending the length of the frame;
a wire configured to run along the length of said filter from a proximal portion to a distal portion, and a distal end of the wire extends further than a distal end of the frame; and
wherein the frame is attached to the wire only at the proximal portion of the frame.