Prosthetic valve with pivoting tissue anchor portions
Prosthetic heart valves and methods of use of prosthetic heart valves may be provided. In one implementation, a prosthetic heart valve may include an annular valve body and atrial anchors and ventricular anchors extending from the valve body. An atrial anchor may include a pivoting portion configured to extend in an upstream direction when the prosthetic heart valve is in a delivery configuration and in a downstream direction when the prosthetic heart valve is in a deployed-anchor configuration. A portion of a ventricular anchor may be configured to abut the annular valve body when the prosthetic heart valve is arranged in the delivery configuration.
1. A prosthetic heart valve, comprising:
an annular valve body having a lumen extending between an upstream end of the annular valve body and a downstream end of the annular valve body;
a plurality of atrial anchors extending from the annular valve body, each atrial anchor having a proximal end secured to the annular valve body and a terminal end opposite from the proximal end; and
a plurality of ventricular anchors extending from the annular valve body, each ventricular anchor having a proximal end secured to the annular valve body and a terminal end opposite from the proximal end, wherein
the prosthetic heart valve is configured to be arranged in:
a delivery configuration in which the atrial anchors and ventricular anchors are configured to be contained at least partially within a delivery device and are arranged in respective delivery positions, and
a deployed-anchor configuration in which the atrial anchors and the ventricular anchors move radially outward from their respective delivery positions,
at least one atrial anchor includes a pivoting portion configured to extend from the annular valve body in an upstream direction when the prosthetic heart valve is in the delivery configuration and to extend from the annular valve body in a downstream direction when the prosthetic heart valve is in the deployed-anchor configuration, and
a first portion of at least one ventricular anchor is configured to abut the annular valve body when the prosthetic heart valve is in the delivery configuration and a second portion of the at least one ventricular anchor is configured to be situated upstream from at least part of the pivoting portion of the at least one atrial anchor when the prosthetic heart valve is in the deployed-anchor configuration.
2. The prosthetic heart valve of claim 1 , wherein the at least one atrial anchor and the at least one ventricular anchor are configured to extend from the annular valve body in an upstream direction parallel to a longitudinal axis of the annular valve body when the prosthetic heart valve is in the delivery configuration.
3. The prosthetic heart valve of claim 1 , wherein the first portion of the at least one ventricular anchor is arranged between the second portion and the proximal end of the at least one ventricular anchor.
4. The prosthetic heart valve of claim 1 , wherein the terminal end of the at least one atrial anchor is configured to be situated at a position upstream and radially-outward from the pivoting portion of the at least one atrial anchor, relative to a longitudinal axis of the annular valve body, when the prosthetic heart valve is in the deployed-anchor configuration.
5. The prosthetic heart valve of claim 1 , wherein the prosthetic heart valve is additionally configured to be arranged in a fully-expanded configuration, the annular valve body having a larger diameter when the prosthetic heart valve is in the fully-expanded configuration than when the prosthetic heart valve is in the delivery and deployed-anchor configurations.
6. The prosthetic heart valve of claim 5 , wherein the diameter of the annular valve body remains constant when the prosthetic heart valve transitions from the delivery configuration to the deployed-anchor configuration.
7. The prosthetic heart valve of claim 5 , wherein
the pivoting portion of the at least one atrial anchor is configured to extend from the annular valve body in a downstream direction when the prosthetic heart valve is in the fully-expanded configuration, and
the terminal end of the at least one atrial anchor is configured to be situated radially-outward from the pivoting portion of the at least one atrial anchor, relative to a longitudinal axis of the annular valve body, when the prosthetic heart valve is in the fully-expanded configuration.
8. The prosthetic heart valve of claim 1 , wherein the at least one atrial anchor includes an upstanding portion configured to extend in an upstream direction when the prosthetic heart valve is in the deployed-anchor configuration, the upstanding portion including the terminal end of the at least one atrial anchor.
9. The prosthetic heart valve of claim 1 , wherein the annular valve body comprises:
an annular outer frame; and
an inner frame positioned at least partially within the annular outer frame, wherein
the plurality of ventricular anchors extend from the annular outer frame and the plurality of atrial anchors extend from the inner frame.
10. The prosthetic heart valve of claim 9 , wherein the portion of the at least one ventricular anchor is configured to abut a portion of the inner frame when the prosthetic heart valve is in the delivery configuration.