Compounds useful in HIV therapy
The invention relates a compound of the formula: a pharmaceutically acceptable salt thereof, compositions thereof, and methods of therapeutic treatment using the same.
1. A compound having the structure:
or a pharmaceutically acceptable salt thereof.
2. A salt according to claim 1 , wherein the salt is present as a hydrochloride salt.
3. The salt according to claim 2 , wherein the hydrochloride salt is a dihydrochloride salt.
4. A pharmaceutical composition comprising a compound according to claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
5. The composition according to claim 4 , wherein said composition is adapted for parenteral administration.
6. A method of depleting latent HIV infected cells comprising administering to a subject a compound of claim 1 , or a pharmaceutically acceptable salt thereof.
7. A method of treating an HIV infection in a subject comprising administering to the subject a compound of claim 1 , or a pharmaceutically acceptable salt thereof.
8. A compound having the structure:
9. A pharmaceutical composition comprising a compound according to claim 8 , and a pharmaceutically acceptable excipient.
10. The composition according to claim 9 , wherein said composition is adapted for parenteral administration.
11. A method of depleting latent HIV infected cells comprising administering to a subject a compound of claim 8 .
12. A method of treating an HIV infection in a subject comprising administering to the subject a compound of claim 8 .