IP Library Granted Patent US 11,898,645
Granted Patent B2
US 11,898,645 · App. 16/930,300 · Granted Feb 13, 2024

Valve assembly with directional flow path

Inventors: Michael C. Gagne (Carson City, NV); Steven V. Cates (Lakewood, CA); Dean C. Richards (Simi Valley, CA); Scott Bendon (Wales, GB)
Assignee: REPLIGEN CORPORATION
F16K11/22B29C45/14614B29C66/01F16K7/06F16K7/07F16K27/003F16K27/0236F16B13/00
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,898,645
App. No.
16/930,300
Granted
Feb 13, 2024
Kind
B2
Abstract

A valve assembly with a multidirectional flow path includes a valve body that includes respective hinged portions defining respective passageways extending through the valve body when in a closed state. A flexible conduit or tubing having a loop portion and a plurality of branches extending from the loop portion is at least partially positioned within the valve body. Portions of the loop that extend beyond the valve body are encapsulated by respective rigid jackets. Multiple valves are situated on the valve body and are used to selectively pinch the loop portion in different pinching configurations to direct fluid to or from the particular branches. The valve assembly may be integrated into a manufacturing or other production process with optional additional jackets used to encapsulate the flexible conduit branches.

Claims (28)

1. A method of making a flexible conduit having a loop portion comprising:

providing a double cross shaped section of tubing;

providing a first Y or TEE section of tubing and a second Y or TEE section of tubing;

securing one end of the first Y or TEE section to the double cross shaped section of tubing via a first overmolded connector;

securing one end of the second Y or TEE section to the double cross shaped section of tubing via a second overmolded connector;

securing a second end of the first Y or TEE section to the double cross shaped section of tubing via a third overmolded connector; and

securing a second end of the second Y or TEE section to the double cross shaped section of tubing via a fourth overmolded connector;

wherein, when connected, the double cross shaped section, the first Y or TEE section, and the second Y or TEE section are three separate flexible tubing pieces that are bonded together via the first, second, third, and fourth overmolded connectors with the intersection between the double cross shaped section and the first Y or TEE section and the second Y or TEE section being spaced apart to leave a flexible tubing portion adjacent the intersections to minimize hold up volumes within the flexible conduit along the intersections when closed by a plurality of valves positioned around the intersections.

2. The method of claim 1 , wherein a mandrel is positioned inside the first Y or TEE section and inside the double cross shaped section while forming the first overmolded connector in a molding operation followed by removal of the mandrel.

3. The method of claim 1 , wherein a mandrel is positioned inside the second Y or TEE section and inside the double cross shaped section while forming the second overmolded connector in a molding operation followed by removal of the mandrel.

4. The method of claim 1 , wherein a mandrel is positioned inside the first Y or TEE section and inside the double cross shaped section while forming the third overmolded connector in a molding operation followed by removal of the mandrel.

5. The method of claim 1 , wherein a mandrel is positioned inside the second Y or TEE section and inside the double cross shaped section while forming the fourth overmolded connector in a molding operation followed by removal of the mandrel.

6. The method of claim 1 , wherein the first, second, third, and fourth overmolded connectors comprise bubble connectors.

7. The method of claim 1 , wherein the first, second, third, and fourth overmolded connectors comprise silicone.

8. A method of making a flexible conduit having a loop portion comprising:

providing a double cross shaped section of tubing;

providing a first Y or TEE section of tubing and a second Y or TEE section of tubing;

securing one end of the first Y or TEE section to the double cross shaped section of tubing via a first overmolded connector;

securing one end of the second Y or TEE section to the double cross shaped section of tubing via a second overmolded connector;

securing a second end of the second Y or TEE section to the double cross shaped section of tubing via a third overmolded connector; and

securing a second end of the first Y or TEE section to the double cross shaped section of tubing via a fourth overmolded connector;

wherein, when connected, the double cross shaped section, the first Y or TEE section, and the second Y or TEE section are three separate flexible tubing pieces that are bonded together via the first, second, third, and fourth overmolded connectors with the intersection between the double cross shaped section and the first Y or TEE section and the second Y or TEE section being spaced apart to leave a flexible tubing portion adjacent the intersections to minimize hold up volumes within the flexible conduit along the intersections when closed by a plurality of valves positioned around the intersections.

9. The method of claim 8 , wherein a mandrel is positioned inside the first Y or TEE section and inside the double cross shaped section while forming the first overmolded connector in a molding operation followed by removal of the mandrel.

10. The method of claim 8 , wherein a mandrel is positioned inside the second Y or TEE section and inside the double cross shaped section while forming the second overmolded connector in a molding operation followed by removal of the mandrel.

11. The method of claim 8 , wherein a mandrel is positioned inside the first Y or TEE section and inside the double cross shaped section while forming the third overmolded connector in a molding operation followed by removal of the mandrel.

12. The method of claim 8 , wherein a mandrel is positioned inside the second Y or TEE section and inside the double cross shaped section while forming the fourth overmolded connector in a molding operation followed by removal of the mandrel.

13. The method of claim 8 , wherein the first, second, third, and fourth overmolded connectors comprise bubble connectors.

14. The method of claim 8 , wherein the first, second, third, and fourth overmolded connectors comprise silicone.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2024
From: ALPHINITY, LLC
To: REPLIGEN CORPORATION
Reel/Frame 068636/0413 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2020
From: ALPHINITY, LLC
To: REPLIGEN CORPORATION
Reel/Frame 054580/0754 →
Continuity (3)
Continuation 15763057
Provisional Application 62236007 · Oct 1, 2015
Related Publication 20210033207A1 · Feb 4, 2021