Multi-axis specimen imaging device with embedded orientation markers
A specimen holding and positioning apparatus operable to substantially non-movably maintain a specimen (e.g., an excised tissue specimen) in a fixed or stable orientation with respect to the apparatus during imaging operations (e.g., x-ray imaging), transport (e.g., from a surgery room to a pathologist's laboratory), and the like for use in facilitating accurate detection and diagnosis of cancers and/or other abnormalities of the specimen.
1. An apparatus for retaining a tissue specimen for imaging, comprising:
a first positioning member configured to receive a tissue specimen;
a second positioning member to be removably coupled to the first positioning member;
an orientation marker disposed within a volume defined by the first positioning member and the second positioning member, wherein the orientation marker is less radiolucent than the first positioning member and the second positioning member; and
a plurality of indicators disposed within the volume defined by the first positioning member and the second positioning member, wherein at least one of the plurality of indicators is configured to convey a location of the orientation marker.
2. The apparatus of claim 1 , wherein the orientation marker disposed within the volume is embedded within the first positioning member.
3. The apparatus of claim 1 , wherein the first positioning member includes an upper surface that is penetrated by the second positioning member when the first positioning member and the second positioning member are removably coupled.
4. The apparatus of claim 1 , wherein the first positioning member includes an opening to receive the tissue specimen.
5. The apparatus of claim 4 , wherein the opening of the first positioning member is defined by at least one sidewall.
6. The apparatus of claim 5 , wherein the at least one sidewall is configured to space the orientation marker from the tissue specimen received in the opening.
7. The apparatus of claim 1 , wherein the first positioning member and the second positioning member comprise a polymeric material.
8. The apparatus of claim 1 , wherein, when the second positioning member is removably coupled to the first positioning member, the first positioning member and the second positioning member are fixably positioned relative to each other.
9. The apparatus of claim 1 , further comprising:
a second orientation marker disposed within the volume.
10. The apparatus of claim 9 , wherein the second orientation marker disposed within the volume is embedded within the second positioning member.
11. An apparatus for retaining a tissue specimen for imaging, comprising:
a first positioning member having a body with a support surface for contacting a tissue specimen;
an orientation marker on the first positioning member, wherein the orientation marker is less radiolucent than the body;
a plurality of indicators on the first positioning member, wherein at least one of the plurality of indicators is configured to convey a location of the orientation marker; and
a retention member insertable into the body of the first positioning member to removably secure the tissue specimen relative to the first positioning member.
12. The apparatus of claim 11 , wherein the first positioning member comprises a polymeric material.
13. The apparatus of claim 12 , wherein the polymeric material is foam.
14. The apparatus of claim 11 , wherein the orientation marker is at least one of:
a grid;
an ink drop; and
an indicia of orientation relative to breast tissue of a patient.
15. The apparatus of claim 11 , wherein the retention member is coupled to a second positioning member.
16. The apparatus of claim 15 , wherein, when the retention member is inserted into the first positioning member, the tissue specimen is secured between the first positioning member and the second positioning member.
17. The apparatus of claim 15 , wherein the first positioning member, the second positioning member, and the retention member are radiolucent.
18. The apparatus of claim 15 , wherein, when the retention member is inserted into the first positioning member, the first positioning member and the second positioning member are fixably positioned relative to each other.
19. The apparatus of claim 11 , wherein the support surface of the first positioning member defines a support plane, and wherein the retention member penetrates the support plane when inserted into the first positioning member.
20. The apparatus of claim 11 , the apparatus further comprising:
another orientation marker disposed within the retention member.