IP Library Granted Patent US 11,666,698
Granted Patent B2
US 11,666,698 · App. 16/940,514 · Granted Jun 6, 2023

Moving basal engine for a fluid delivery device

Inventor: Robert R. Gonnelli (Mahwah, NJ)
Assignee: Mannkind Corporation
A61M5/1452A61M5/14248A61M5/14526A61M5/3159A61M5/31526A61M5/31533A61M5/31578A61M5/1454A61M5/14244A61M2005/1405A61M2005/14204A61M2005/14506A61M2005/14513
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Quick Facts
Patent No.
US 11,666,698
App. No.
16/940,514
Granted
Jun 6, 2023
Kind
B2
Abstract

A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.

Claims (19)

1. A fluid delivery device comprising:

a fluid reservoir for containing medicament, the fluid reservoir being sealed proximate one end with a sliding seal piston;

a delivery path configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device;

a basal engine mechanism configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate; and

a bolus mechanism, containing the basal engine mechanism, configured to directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time,

wherein the basal engine mechanism includes a reservoir containing a hydraulic fluid under pressure from a stored energy source including one or more springs, the reservoir of the basal engine mechanism including an aperture configured to release the hydraulic fluid at a rate determined by a force of the stored energy source, a viscosity of the hydraulic fluid and a geometry of the aperture,

wherein the hydraulic fluid that is released by the reservoir of the basal engine mechanism presses on the sliding seal piston, and

wherein the hydraulic fluid is also between the basal engine mechanism and the sliding seal piston.

2. The fluid delivery device of claim 1 , wherein the bolus mechanism slides within the fluid reservoir.

3. The fluid delivery device of claim 1 , wherein the sliding seal piston is in contact with the basal engine mechanism and the medicament.

4. The fluid delivery device of claim 1 , wherein the basal engine mechanism includes the sliding seal piston.

5. The fluid delivery device of claim 1 , wherein the basal engine mechanism includes a sliding seal, the sliding seal being in contact with the hydraulic fluid that is in contact with the sliding seal piston.

6. The fluid delivery device of claim 1 , wherein the fluid reservoir is contained within a housing having an adhesive patch configured to be adhered to a skin surface of the patient.

7. The fluid delivery device of claim 1 , wherein the delivery path includes a needle.

8. The fluid delivery device of claim 1 , wherein the bolus mechanism comprises a plunger, wherein depression of the plunger is configured to move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.

9. The fluid delivery device of claim 8 , wherein the bolus mechanism further comprises a pawl, having an end, for preventing a backward motion of the plunger.

10. The fluid delivery device of claim 8 , wherein a distance that the plunger can be depressed in one application of force is limited.

11. The fluid delivery device of claim 8 , wherein a distance the plunger can be depressed is configured to be limited each time a release element is actuated.

12. The fluid delivery device of claim 1 , wherein the hydraulic fluid that is released by the reservoir of the basal engine mechanism passes through the aperture and enters a space between the sliding seal piston and the reservoir of the basal engine mechanism.

Assignments (6)
PATENT SECURITY AGREEMENT Recorded Aug 12, 2025
From: MANNKIND CORPORATION
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 072444/0525 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 2, 2022
From: ZEALAND PHARMA A/S
To: MANNKIND CORPORATION
Reel/Frame 060984/0295 →
RELEASE OF SECURITY INTEREST Recorded Aug 24, 2022
From: ZOOLANDER SA LLC
To: ZEALAND PHARMA A/S
Reel/Frame 060887/0685 →
PATENT SECURITY AGREEMENT Recorded Dec 27, 2021
From: ZEALAND PHARMA A/S
To: ZOOLANDER SA LLC
Reel/Frame 058593/0261 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2020
From: GONNELLI, ROBERT R.
To: VALERITAS, INC.
Reel/Frame 053367/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2020
From: VALERITAS, INC.
To: ZEALAND PHARMA A/S
Reel/Frame 053367/0348 →