Method for preventing or treating Alzheimer's disease
The present invention is directed to a method for preventing and/or treating Alzheimer's disease. The method comprises administering to a subject in need thereof an effective amount of dapansutrile. The method reduces neuroinflammation and improves the cognitive functions such as learning and memory processes of the subject. Dapansutrile can be administered to the subject orally at a dose of 100-2000 mg/day for 3 months to 5 years or longer.
1. A method for treating Alzheimer's disease, comprising the step of:
administering to a subject in need thereof an effective amount of dapansutrile, or a pharmaceutically acceptable solvate thereof.
2. The method according to claim 1 , wherein said method reduces neuroinflammation in the subject.
3. The method according to claim 1 , wherein said method improves the cognitive functions of the subject.
4. The method according to claim 1 , wherein said method improves learning and memory processes of the subject.
5. The method according to claim 1 , wherein dapansutrile is administered to the subject every 1-3 days for 3 months to 5 years.
6. The method according to claim 1 , wherein dapansutrile is administered to the subject 100-2000 mg/day.
7. The method according to claim 1 , wherein the subject is identified by family history, generic screening, clinical signs of memory loss, and/or brain scan.
8. The method according to claim 1 , wherein said compound is administered by systemic administration.
9. The method according to claim 8 , wherein said compound is administered by oral administration.
10. The method according to claim 1 , comprising administering to the subject an effective amount of dapansutrile.