IP Library Granted Patent US 11,554,272
Granted Patent B2
US 11,554,272 · App. 16/944,280 · Granted Jan 17, 2023

System and method for diagnostic and treatment

Inventors: Haining Sun (Shanghai, CN); Guotao Quan (Shanghai, CN); Yuan Bao (Shanghai, CN); Wenjing Cao (Shanghai, CN)
Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
A61N5/1067A61N5/1039G06T5/002G06T5/50G06T7/0014G06T11/00G06T11/006G06T11/008G06V10/24G16H30/20G16H50/20G06T2207/10081G06T2207/20081G06T2207/20084G06T2207/30196G06T2211/424
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,554,272
App. No.
16/944,280
Granted
Jan 17, 2023
Kind
B2
Abstract

A method may include obtaining first image data relating to a region of interest (ROI) of a first subject. The first image data corresponding to a first equivalent dose level may be acquired by a first device. The method may also include obtaining a model for denoising relating to the first image data and determining second image data corresponding to an equivalent dose level higher than the first equivalent dose level based on the first image data and the model for denoising. In some embodiments, the method may further include determining information relating to the ROI of the first subject based on the second image data and recording the information relating to the ROI of the first subject.

Claims (67)

1. A system, comprising

a non-transitory computer-readable storage medium storing executable instructions, and

at least one processor in communication with the non-transitory computer-readable storage medium, when executing the executable instructions, causing the system to implement a method, comprising:

obtaining first projection data relating to a region of interest (ROI) of a subject, the first projection data corresponding to a first equivalent dose level;

obtaining an image reconstruction model using an iterative algorithm, the image reconstruction model being constructed based on at least one of a first statistical model of noises in a projection domain or a second statistical model of noises in an image domain;

processing, based on the first statistical model of noises and a denoising model, the first projection data to obtain second projection data;

generating, based on the second projection data, a first image; and

determining, based on the first image and the second statistical model, the target image relating to the ROI of the subject, the target image corresponding to a second equivalent dose level higher than the first equivalent dose level, wherein the denoising model includes a parameter configured to adjust a strength of denoising the first projection data that is controlled by the first statistical model of noises.

2. The system of claim 1 , wherein the method further includes:

determining, based on the target image, first information relating to the ROI of the subject;

obtaining second information relating to the ROI in a treatment plan of the subject; and

performing at least one of operations based on at least one of the first information or the second information, wherein the operations include:

performing a delivery of treatment radiation beam on the subject;

determining a treatment plan of the subject;

modifying the treatment plan of the subject; and

adjusting a position of the subject in space.

3. The system of claim 1 , wherein the processing, based on the first statistical model of noises and a denoising model, the first projection data to obtain the second projection data includes:

determining, based on the first statistical model of noises, the denoising model; and

denoising the first projection data using the denoising model to obtain the second projection data.

4. The system of claim 1 , wherein the determining, based on the first image and the second statistical model, the target image relating to the ROI of the subject includes:

determining, based on the second statistical model of noises, a second denoising model; and

denoising the first image using the second denoising model to obtain the target image.

5. The system of claim 4 , wherein the second denoising model includes a parameter configured to adjust a strength of denoising the first image that is controlled by the second statistical model of noises.

6. The system of claim 1 , wherein the first equivalent dose level is no less than 15% of the second equivalent dose level.

7. The system of claim 1 , wherein the first equivalent dose level is no less than 50% of the second equivalent dose level.

8. The system of claim 1 , wherein the first equivalent dose level is no less than 85% of the second equivalent dose level.

9. The system of claim 1 , wherein a ratio of the first equivalent dose level to the second equivalent dose level is equal to 1:7.

10. A method, implemented on a computing device having at least one processor and at least one non-transitory computer-readable storage medium, the method comprising:

obtaining first projection data relating to a region of interest (ROI) of a subject, the first projection data corresponding to a first equivalent dose level;

obtaining an image reconstruction model using an iterative algorithm, the image reconstruction model being constructed based on at least one of a first statistical model of noises in a projection domain or a second statistical model of noises in an image domain;

processing, based on the first statistical model of noises and a denoising model, the first projection data to obtain second projection data;

generating, based on the second projection data, a first image; and

determining, based on the first image and the second statistical model, the target image relating to the ROI of the subject, the target image corresponding to a second equivalent dose level higher than the first equivalent dose level, wherein the denoising model includes a parameter configured to adjust a strength of denoising the first projection data that is controlled by the first statistical model of noises.

11. The method of claim 10 , wherein the method further includes:

determining, based on the target image, first information relating to the ROI of the subject;

obtaining second information relating to the ROI in a treatment plan of the subject; and

performing at least one of operations based on at least one of the first information or the second information, wherein the operations include:

performing a delivery of treatment radiation beam on the subject;

determining a treatment plan of the subject;

modifying the treatment plan of the subject; and

adjusting a position of the subject in space.

12. The method of claim 10 , wherein the processing, based on the first statistical model of noises and a denoising model, the first projection data to obtain the second projection data includes:

determining, based on the first statistical model of noises, the denoising model; and

denoising the first projection data using the denoising model to obtain the second projection data.

13. The method of claim 10 , wherein the determining, based on the first image and the second statistical model, the target image relating to the ROI of the subject includes:

determining, based on the second statistical model of noises, a second denoising model; and

denoising the first image using the second denoising model to obtain the target image.

14. The method of claim 13 , wherein the second denoising model includes a parameter configured to adjust a strength of denoising the first image that is controlled by the second statistical model of noises.

15. The method of claim 10 , wherein the first equivalent dose level is no less than 15% of the second equivalent dose level.

16. The method of claim 10 , wherein the first equivalent dose level is no less than 50% of the second equivalent dose level.

17. The method of claim 10 , wherein the first equivalent dose level is no less than 85% of the second equivalent dose level.

18. The method of claim 10 , wherein a ratio of the first equivalent dose level to the second equivalent dose level is equal to 1:7.

19. A non-transitory computer readable medium, comprising:

instructions being executed by at least one processor, causing the at least one processor to implement a method, comprising:

obtaining first projection data relating to a region of interest (ROI) of a subject, the first projection data corresponding to a first equivalent dose level;

obtaining an image reconstruction model using an iterative algorithm, the image reconstruction model being constructed based on at least one of a first statistical model of noises in a projection domain or a second statistical model of noises in an image domain;

processing, based on the first statistical model of noises and a denoising model, the first projection data to obtain second projection data;

generating, based on the second projection data, a first image; and

determining, based on the first image and the second statistical model, the target image relating to the ROI of the subject, the target image corresponding to a second equivalent dose level higher than the first equivalent dose level, wherein the denoising model includes a parameter configured to adjust a strength of denoising the first projection data that is controlled by the first statistical model of noises.

20. The non-transitory computer readable medium of claim 19 , further including:

determining, based on the target image, first information relating to the ROI of the subject;

obtaining second information relating to the ROI in a treatment plan of the subject; and

performing at least one of operations based on at least one of the first information or the second information, wherein the operations include:

performing a delivery of treatment radiation beam on the subject;

determining a treatment plan of the subject;

modifying the treatment plan of the subject; and

adjusting a position of the subject in space.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 27, 2020
From: SUN, HAINING; QUAN, GUOTAO; BAO, YUAN; CAO, WENJING
To: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
Reel/Frame 053609/0828 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 27, 2020
From: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
To: SHENZHEN UNITED IMAGING HEALTHCARE CO., LTD.
Reel/Frame 053609/0833 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 27, 2020
From: SHENZHEN UNITED IMAGING HEALTHCARE CO., LTD.
To: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
Reel/Frame 053609/0840 →
Continuity (3)
Continuation 16222151 · Dec 17, 2018
Continuation PCTCN2017110005 · Nov 8, 2017
Related Publication 20200360730A1 · Nov 19, 2020