NUTRITIONAL SUPPLEMENT FOR IMPROVING SEXUAL HEALTH IN MEN AND WOMEN
The invention provides compositions and methods that are effective to improve NO production in vivo and/or to increase NO levels in blood. Such compositions and methods are useful to improve sexual function in males and females.
1 . A unit dosage form suitable for oral administration to a human comprising:
L-citrulline 500 mg±20 mg;
L-arginine 250 mg±20 mg; and
at least about 5 mg piperine.
2 . The unit dosage form of claim 1 that comprises at least about 5.0 mg piperine.
3 . The unit dosage form of claim 1 that comprises at least about 5.3 mg piperine.
4 . The unit dosage form of claim 1 that comprises at least about 5.5 mg piperine.
5 . The unit dosage form of claim 1 that further comprises microcrystalline cellulose, silicon dioxide, and magnesium stearate.
6 . The unit dosage form of claim 1 that comprises at least about 480 mg of L-citrulline.
7 . The unit dosage form of claim 1 that comprises at least about 490 mg of L-citrulline.
8 . The unit dosage form of claim 1 that comprises at least about 500 mg of L-citrulline.
9 . The unit dosage form of claim 1 that comprises at least about 230 mg of L-arginine.
10 . The unit dosage form of claim 1 that comprises at least about 240 mg of L-arginine.
11 . The unit dosage form of claim 1 that comprises at least about 250 mg of L-arginine.
12 . The unit dosage form of claim 1 that comprises:
about 500 mg of L-citrulline;
about 250 mg of L-arginine; and
about 1.75 mg of bioperine.
13 . The unit dosage form of claim 1 wherein the piperine is synthetically produced piperine.
14 . The unit dosage form of claim 1 the piperine is an extract from the fruit of Piper.
15 . The unit dosage form of claim 12 that further comprises microcrystalline cellulose, silicon dioxide, and magnesium stearate.
16 . The unit dosage form of claim 1 that is formulated as a capsule, powder or liquid.
17 . A method to increase NO levels in the blood of a mammal comprising administering a unit dosage form of claim 1 to the mammal.
18 . A method to treat erectile dysfunction in a mammal comprising administering a unit dosage form of claim 1 to the mammal.
19 . A method to improve sexual function in a mammal comprising administering a unit dosage form of claim 1 to the mammal.
20 . A method to improve erection hardness, erection maintenance, frequency of intercourse, partner satisfaction, or overall satisfaction with sexual health in a male human comprising administering a unit dosage form of claim 1 to the male human.
21 . A method to improve lubrication, sexual desire, ability to be aroused or frequency of intercourse, in a female human comprising administering a unit dosage form of claim 1 to the female human.